MeSH 搜索器

Synucleinopathies

Neurodegenerative disorders involving deposition of abnormal ALPHA-SYNUCLEIN in dopaminergic neurons and glial cells in the brain. Pathological aggregations of alpha-synuclein proteins results in LEWY BODIES and Lewy neurites; melanin granules in the SUBSTANTIA NIGRA and LOCUS COERULEUS; and glial cytoplasmic inclusions. Synucleinopathies are associated with mutation in the ALPHA-SYNUCLEIN (SNCA) gene on chromosome 4. PARKINSON DISEASE; LEWY BODY DISEASE with dementia; and MULTIPLE SYSTEM ATROPHY are prominent examples of synucleinopathy.
推出的年份: 2020
副标题
树号: C10.574.928, C18.452.845.650
MeSH 单一 ID: D000080874
进入的组:
  • Synucleinopathy
  • a-Synucleinopathies
  • a-Synucleinopathy
  • alpha Synuclein Pathology
  • alpha Synuclein Pathologies
  • alpha-Synucleinopathies
  • alpha Synucleinopathies
  • alpha-Synucleinopathy
早前的内容:
  • Neurodegenerative Diseases (1998-2019)
  • alpha-Synuclein (1999-2019)

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