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Mutagenesis, Insertional

Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
推出的年份: 1991
副标题
树号: E05.393.420.601.550, G05.365.590.575, G05.558.550
MeSH 单一 ID: D016254
进入的组:
  • Insertional Mutagenesis
  • Sequence Insertion
  • Insertion, Sequence
  • Insertions, Sequence
  • Sequence Insertions
  • Viral Insertional Mutagenesis
  • Insertional Mutagenesis, Viral
  • Mutagenesis, Viral Insertional
  • Linker-Insertion Mutagenesis
  • Linker Insertion Mutagenesis
  • Mutagenesis, Linker-Insertion
  • Gene Insertion
  • Gene Insertions
  • Insertion, Gene
  • Insertions, Gene
  • Insertion Mutation
  • Insertion Mutations
  • Mutation, Insertion
  • Mutations, Insertion
  • Insertional Activation
  • Activation, Insertional
  • Activations, Insertional
  • Insertional Activations
  • Mutagenesis, Cassette
  • Cassette Mutagenesis
早前的内容:
  • DNA Insertion Elements (1983-1990)
  • Mutation (1982-1990)

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