MeSH 搜索器

Teniposide

A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle.
推出的年份: 1991(1981)
副标题
树号: D09.408.348.800
MeSH 单一 ID: D013713
进入的组:
  • Demethyl Epipodophyllotoxin Thenylidine Glucoside
  • Vumon
  • VM-26
  • VM 26
  • VM26
  • Teniposide, (5a alpha,9 alpha(S*))-Isomer
  • NSC-122819
  • NSC 122819
  • NSC122819
早前的内容:
  • Glucosides (1975)
  • Glycosides (1973-1974)
  • Podophyllotoxin (1973-1974)

留言 (0)

沒有登入
gif