aDepartment of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Hospital

bDepartment of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Homburg, Germany

cDepartment of Dermatology, Copenhagen University Hospital - Bispebjerg

dDepartment of Pharmacy, University of Copenhagen, Copenhagen, Denmark

eDepartment of Adult and Pediatric Dermatology, Venereology, Allergology, Saarland University Hospital, Homburg, Germany

Correspondence to Felix Götzinger, MD, Department for Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, IMED, Geb. 41, Kirrberger Str. 1, University Hospital Saarland, Saarland University, Homburg 66424, Germany. Tel: +4968411615911; fax: +4968411615910; e-mail: [email protected]

Abbreviations: ANOVA, analysis of variance; BP, blood pressure; DMEM, Dulbecco's modified eagle's medium; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HCT, hydrochlorothiazide; IQR, interquartile range; MED, minimal erythema dose; MPD, minimal pigmentation dose; RT-PCR, real-time PCR; SD, standard deviation; UVA, ultraviolet radiation type A; UVB, ultraviolet radiation type B; UVR, ultraviolet radiation; 25(OH)D, 25-hydroxy-vitamin D3

Received 17 May, 2023

Revised 15 July, 2023

Accepted 15 August, 2023

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