Does COVID-19 Infection Increase the Risk of Diabetes? Current Evidence

WHO Coronavirus (COVID-19) dashboard. World Health Organization. 2023. https://covid19.who.int/. Accessed 5 Apr 2023

Singh AK, Gupta R, Ghosh A, Misra A. Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations. Diabetes Metab Syndr. 2020;14:303–10.

Article  PubMed  PubMed Central  Google Scholar 

Abdelhafiz AH, Emmerton D, Sinclair AJ. Diabetes in COVID-19 pandemic-prevalence, patient characteristics and adverse outcomes. Int J Clin Pract. 2021;75:e14112.

Article  CAS  PubMed  Google Scholar 

Nassar M, Daoud A, Nso N, Medina L, Ghernautan V, Bhangoo H, et al. Diabetes mellitus and COVID-19: review article. Diabetes Metab Syndr. 2021;15:102268.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wong R, Hall M, Vaddavalli R, Anand A, Arora N, Bramante CT, et al. Glycemic control and clinical outcomes in US patients with COVID-19: data from the National COVID Cohort Collaborative (N3C) database. Diabetes Care. 2022;45(5):1099–106.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rubino F, Amiel SA, Zimmet P, Alberti G, Bornstein S, Eckel RH, et al. New-onset diabetes in Covid-19. N Engl J Med. 2020;383:789–90.

Article  PubMed  Google Scholar 

Unnikrishnan R, Misra A. Diabetes and COVID19: a bidirectional relationship. Nutr Diabetes. 2021;11(1):21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khunti K, Del Prato S, Mathieu C, Kahn SE, Gabbay RA, Buse JB. COVID-19, Hyperglycemia, and New-Onset Diabetes. Diabetes Care. 2021;44:2645–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al KJ. Epidemiology of Type 2 diabetes - global burden of disease and forecasted trends. J Epidemiol Glob Health. 2020;10:107–11.

Article  PubMed  PubMed Central  Google Scholar 

Fignani D, Licata G, Brusco N, Nigi L, Grieco GE, Marselli L, et al. SARS-CoV-2 receptor angiotensin I-converting enzyme type 2 (ACE2) is expressed in human pancreatic β-cells and in the human pancreas microvasculature. Front Endocrinol. 2020;11:596898.

Article  Google Scholar 

Aluganti Narasimhulu C, Singla DK. Mechanisms of COVID-19 pathogenesis in diabetes. Am J Physiol-Heart Circ Physiol. 2022;323:H403–20.

Article  PubMed  PubMed Central  Google Scholar 

Liu F, Long X, Zhang B, Zhang W, Chen X, Zhang Z. ACE2 expression in pancreas may cause pancreatic damage after SARS-CoV-2 infection. Clin Gastroenterol Hepatol. 2020;18:2128-30.e2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Müller JA, Groß R, Conzelmann C, Krüger J, Merle U, Steinhart J, et al. SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas. Nat Metab. 2021;3:149–65.

Article  PubMed  Google Scholar 

Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, et al. SARS-CoV-2 cell entry factors ACE2 and TMPRSS2 are expressed in the microvasculature and ducts of human pancreas but are not enriched in β cells. Cell Metab. 2020;32(6):1028-1040.e4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vas P, Hopkins D, Feher M, Rubino F, B Whyte M. Diabetes, obesity and COVID-19: A complex interplay. Diabetes Obes Metab. 2020;22:1892–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bornstein SR, Dalan R, Hopkins D, Mingrone G, Boehm BO. Endocrine and metabolic link to coronavirus infection. Nat Rev Endocrinol. 2020;16:297–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Groop LC, Bonadonna RC, DelPrato S, Ratheiser K, Zyck K, Ferrannini E, et al. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest. 1989;84:205–13.

Article  CAS  PubMed  PubMed Central  Google Scholar 

He X, Liu C, Peng J, Li Z, Li F, Wang J, et al. COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors. Signal Transduct Target Ther. 2021;6:427.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Metwally AA, Mehta P, Johnson BS, Nagarjuna A, Snyder MP. COVID-19–induced new-onset diabetes: trends and technologies. Diabetes. 2021;70:2733–44.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reiterer M, Rajan M, Gómez-Banoy N, Lau JD, Gomez-Escobar LG, Gilani A, et al. Hyperglycemia in acute COVID-19 is characterized by adipose tissue dysfunction and insulin resistance. Cell Metab. 2021;33(11):2174-2188.e5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen M, Zhu B, Chen D, Hu X, Xu X, Shen W-J, et al. COVID-19 may increase the risk of insulin resistance in adult patients without diabetes: a 6-month prospective study. Endocr Pract. 2021;27:834–41.

Article  PubMed  PubMed Central  Google Scholar 

Montefusco L, Ben Nasr M, D’Addio F, Loretelli C, Rossi A, Pastore I, et al. Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection. Nat Metab. 2021;3:774–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wan L, Gao Q, Deng Y, Ke Y, Ma E, Yang H, et al. GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia. Nat Metab. 2022;4:29–43.

Article  CAS  PubMed  Google Scholar 

Petersen MC, Vatner DF, Shulman GI. Regulation of hepatic glucose metabolism in health and disease. Nat Rev Endocrinol. 2017;13:572–87.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gerganova A, Assyov Y, Kamenov Z. Stress hyperglycemia, diabetes mellitus and COVID-19 infection: risk factors, clinical outcomes and post-discharge implications. Front Clin Diabetes Healthc. 2022;3:826006.

Article  PubMed  PubMed Central  Google Scholar 

Liu X-X, Zhu X-M, Miao Q, Ye H-Y, Zhang Z-Y, Li Y-M. Hyperglycemia induced by glucocorticoids in nondiabetic patients: a meta-analysis. Ann Nutr Metab. 2014;65:324–32.

Article  CAS  PubMed  Google Scholar 

Laurenzi A, Caretto A, Molinari C, Mercalli A, Melzi R, Nano R, et al. No evidence of long-term disruption of glycometabolic control after SARS-CoV-2 infection. J Clin Endocrinol Metab. 2022;107:e1009–19.

Article  PubMed  Google Scholar 

Cromer SJ, Colling C, Schatoff D, Leary M, Stamou MI, Selen DJ, et al. Newly diagnosed diabetes vs. pre-existing diabetes upon admission for COVID-19: associated factors, short-term outcomes, and long-term glycemic phenotypes. J Diabetes Complications. 2022;36:108145.

Article  PubMed  PubMed Central  Google Scholar 

Op de Beeck A, Eizirik DL. Viral infections in type 1 diabetes mellitus–why the β cells? Nat Rev Endocrinol. 2016;12:263–73.

Article  CAS  PubMed  Google Scholar 

Caruso P, Longo M, Esposito K, Maiorino MI. Type 1 diabetes triggered by covid-19 pandemic: a potential outbreak? Diabetes Res Clin Pract. 2020;164:108219.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marchand L, Pecquet M, Luyton C. Type 1 diabetes onset triggered by COVID-19. Acta Diabetol. 2020;57:1265–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Genç S, Evren B, Bozbay A, Aydın EŞ, Genç Ö, Şahin I. Could COVID-19 trigger type 1 diabetes? Presentation of COVID-19 case presented with diabetic ketoacidosis. Acta Endocrinol. 2021;17:532–6.

Google Scholar 

Anindya R, Rutter GA, Meur G. New-onset type 1 diabetes and severe acute respiratory syndrome coronavirus 2 infection. Immunol Cell Biol. 2023;101:191–203.

Article  CAS  PubMed  Google Scholar 

Tison GH, Barrios J, Avram R, Kuhar P, Bostjancic B, Marcus GM, et al. Worldwide physical activity trends since COVID-19 onset. Lancet Glob Health. 2022;10:e1381–2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abed Alah M, Abdeen S, Kehyayan V, Bougmiza I. Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: perceived changes in diet, physical activity, and body weight. Prev Med Rep. 2021;24:101545.

Article  PubMed  PubMed Central  Google Scholar 

Lange SJ, Kompaniyets L, Freedman DS, Kraus EM, Porter R, DNP3, et al. Longitudinal trends in body mass index before and during the COVID-19 pandemic among persons aged 2–19 years - United States, 2018–2020. MMWR Morb Mortal Wkly Rep. 2021;70:1278–83.

Article  CAS 

留言 (0)

沒有登入
gif