Abbott, N. J. Blood–brain barrier structure and function and the challenges for CNS drug delivery. J. Inherit. Metab. Dis. 36, 437–449 (2013).
Article CAS PubMed Google Scholar
Abbott, N. J., Patabendige, A. A. K., Dolman, D. E. M., Yusof, S. R. & Begley, D. J. Structure and function of the blood–brain barrier. Neurobiol. Dis. 37, 13–25 (2010).
Article CAS PubMed Google Scholar
Ballabh, P., Braun, A. & Nedergaard, M. The blood–brain barrier: an overview: Structure, regulation, and clinical implications. Neurobiol. Dis. 16, 1–13 (2004).
Article CAS PubMed Google Scholar
Pandit, R., Chen, L. & Götz, J. The blood-brain barrier: physiology and strategies for drug delivery. Adv. Drug Deliv. Rev. 165-166, 1–14 (2020).
Article CAS PubMed Google Scholar
Banks, W. A. From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery. Nat. Rev. Drug Discov. 15, 275–292 (2016).
Article CAS PubMed Google Scholar
Shaw, A. T., Yasothan, U. & Kirkpatrick, P. Crizotinib. Nat. Rev. Drug Discov. 10, 897–898 (2011).
Article CAS PubMed Google Scholar
Alauddin, M. M., Radaram, B., Rao, Y., Yang, P. & Piwnica-Worms, D. Novel derivatives of anaplastic lymphoma kinase inhibitors: synthesis, radiolabeling and preliminary biological studies on crizotinib and alectinib analogues. Cancer Res. 79, 10–10 (2019).
Fromm, M. F. Importance of P-glycoprotein at blood–tissue barriers. Trends Pharmacol. Sci. 25, 423–429 (2004).
Article CAS PubMed Google Scholar
Endicott, J. A. & Ling, V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 58, 137–171 (1989).
Article CAS PubMed Google Scholar
Choudhari, M. et al. Evolving new-age strategies to transport therapeutics across the blood-brain-barrier. Int. J. Pharm. 599, 120351 (2021).
Article CAS PubMed Google Scholar
Sweeney, M. D., Sagare, A. P. & Zlokovic, B. V. Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders. Nat. Rev. Neurol. 14, 133–150 (2018).
Article CAS PubMed PubMed Central Google Scholar
Arvanitis, C. D., Ferraro, G. B. & Jain, R. K. The blood–brain barrier and blood–tumour barrier in brain tumours and metastases. Nat. Rev. Cancer 20, 26–41 (2020).
Article CAS PubMed Google Scholar
Tang, W. et al. Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics. Chem. Soc. Rev. 48, 2967–3014 (2019).
Article CAS PubMed Google Scholar
D’Souza, A., Dave, K. M., Stetler, R. A. & S. Manickam, D. Targeting the blood-brain barrier for the delivery of stroke therapies. Adv. Drug Deliv. Rev. 171, 332–351 (2021).
Terstappen, G. C., Meyer, A. H., Bell, R. D. & Zhang, W. Strategies for delivering therapeutics across the blood–brain barrier. Nat. Rev. Drug Discov. 20, 362–383 (2021).
Article CAS PubMed Google Scholar
Zhao, Z., Ukidve, A., Kim, J. & Mitragotri, S. Targeting strategies for tissue-specific drug delivery. Cell 181, 151–167 (2020).
Article CAS PubMed Google Scholar
Liu, Y., Castro Bravo, K. M. & Liu, J. Targeted liposomal drug delivery: a nanoscience and biophysical perspective. Nanoscale Horiz. 6, 78–94 (2021).
Article CAS PubMed Google Scholar
Hwang, D., Ramsey, J. D. & Kabanov, A. V. Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval. Adv. Drug Deliv. Rev. 156, 80–118 (2020).
Article CAS PubMed PubMed Central Google Scholar
Wang, H., Chen, Q. & Zhou, S. Carbon-based hybrid nanogels: a synergistic nanoplatform for combined biosensing, bioimaging, and responsive drug delivery. Chem. Soc. Rev. 47, 4198–4232 (2018).
Article CAS PubMed Google Scholar
Mitchell, M. J. et al. Engineering precision nanoparticles for drug delivery. Nat. Rev. Drug Discov. 20, 101–124 (2021).
Article CAS PubMed Google Scholar
Zou, Y., Huang, B., Cao, L., Deng, Y. & Su, J. Tailored mesoporous inorganic biomaterials: assembly, functionalization, and drug delivery engineering. Adv. Mater. 33, 2005215 (2021).
Wu, F. & Liu, J. Decorated bacteria and the application in drug delivery. Adv. Drug Deliv. Rev. 188, 114443 (2022).
Article CAS PubMed Google Scholar
Le, Q. V., Lee, J., Lee, H., Shim, G. & Oh, Y. K. Cell membrane-derived vesicles for delivery of therapeutic agents. Acta Pharm. Sin. B 11, 2096–2113 (2021).
Article CAS PubMed PubMed Central Google Scholar
Liang, Y., Duan, L., Lu, J. & Xia, J. Engineering exosomes for targeted drug delivery. Theranostics 11, 3183–3195 (2021).
Article CAS PubMed PubMed Central Google Scholar
Bentivoglio, M. & Kristensson, K. Tryps and trips: cell trafficking across the 100-year-old blood–brain barrier. Trends Neurosci. 37, 325–333 (2014).
Article CAS PubMed PubMed Central Google Scholar
Liebner, S., Czupalla, C. J. & Wolburg, H. Current concepts of blood-brain barrier development. Int. J. Dev. Biol. 55, 467–476 (2011).
Article CAS PubMed Google Scholar
Upton, D. H. et al. Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy. Theranostics 12, 4734–4752 (2022).
Article CAS PubMed PubMed Central Google Scholar
Harati, R., Villégier, A.-S., Banks, W. A. & Mabondzo, A. Susceptibility of juvenile and adult blood–brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity. J. Neuroinflammation 9, 273 (2012).
Article CAS PubMed PubMed Central Google Scholar
Cai, Z. et al. Role of blood-brain barrier in Alzheimer’s disease. J. Alzheimers Dis. 63, 1223–1234 (2018).
Article CAS PubMed Google Scholar
Eichler, A. F. et al. The biology of brain metastases-translation to new therapies. Nat. Rev. Clin. Oncol. 8, 344–356 (2011).
Article CAS PubMed PubMed Central Google Scholar
Saraiva, C. et al. Nanoparticle-mediated brain drug delivery: overcoming blood–brain barrier to treat neurodegenerative diseases. J. Control. Release 235, 34–47 (2016).
Article CAS PubMed Google Scholar
Greene, C. & Campbell, M. Tight junction modulation of the blood brain barrier: CNS delivery of small molecules. Tissue Barriers 4, e1138017 (2016).
Article PubMed PubMed Central Google Scholar
Ruan, S., Zhou, Y., Jiang, X. & Gao, H. Rethinking CRITID procedure of brain targeting drug delivery: circulation, blood brain barrier recognition, intracellular transport, diseased cell targeting, internalization, and drug release. Adv. Sci. 8, 2004025 (2021).
Zheng, M. et al. Tuning the elasticity of polymersomes for brain tumor targeting. Adv. Sci. 8, e2102001 (2021).
Song, Y., Hu, C., Fu, Y. & Gao, H. Modulating the blood–brain tumor barrier for improving drug delivery efficiency and efficacy. VIEW 3, 20200129 (2022).
Begley, D. J. Delivery of therapeutic agents to the central nervous system: the problems and the possibilities. Pharmacol. Ther. 104, 29–45 (2004).
Article CAS PubMed Google Scholar
Zhou, Y., Peng, Z., Seven, E. S. & Leblanc, R. M. Crossing the blood-brain barrier with nanoparticles. J. Control. Release 270, 290–303 (2018).
Article CAS PubMed Google Scholar
Kadry, H., Noorani, B. & Cucullo, L. A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity. Fluids Barriers CNS 17, 69 (2020).
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