Bulusu KC, Guha R, Mason DJ, Lewis RP, Muratov E, KalantarMotamedi Y, Cokol M, Bender A (2016) Modelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectives. Drug Discov Today 21:225–38
Article CAS PubMed Google Scholar
Cahill KE, Morshed RA, Yamini B (2016) Nuclear factor-kappaB in glioblastoma: insights into regulators and targeted therapy. Neuro Oncol 18:329–339
Article CAS PubMed Google Scholar
Ding L, Jiang P, Xu X, Lu W, Yang C, Zhou P, Liu S (2020) Resveratrol promotes HSV-2 replication by increasing histone acetylation and activating NF-kappaB. Biochem Pharmacol 171:113691
Article CAS PubMed Google Scholar
Goodenberger ML, Jenkins RB (2012) Genetics of Adult Glioma. Cancer Genet 205:613–621
Article CAS PubMed Google Scholar
Grossman SA, Ye X, Piantadosi S, Desideri S, Nabors LB, Rosenfeld M, Fisher J, N.C. Consortium (2010) Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. Clin Cancer Res 16:2443–9
Article CAS PubMed PubMed Central Google Scholar
Harris IS, DeNicola GM (2020) The complex interplay between antioxidants and ROS in cancer. Trends Cell Biol 30:440–451
Article CAS PubMed Google Scholar
Hu M, Yu Z, Mei P, Li J, Luo D, Zhang H, Zhou M, Liang F, Chen R (2020) Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer. Aging 12:138–155
Article CAS PubMed PubMed Central Google Scholar
Jalili-Nik M, Sadeghi MM, Mohtashami E, Mollazadeh H, Afshari AR, Sahebkar A (2020) Zerumbone promotes cytotoxicity in human malignant glioblastoma cells through reactive oxygen species (ROS) generation. Oxid Med Cell Longev 2020:3237983
Article PubMed PubMed Central Google Scholar
Li C, Deng C, Pan G, Wang X, Zhang K, Dong Z, Zhao G, Tan M, Hu X, Shi S, Du J, Ji H, Wang X, Yang L, Cui H (2020) Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer. J Exp Clin Cancer Res 39:230
Article CAS PubMed PubMed Central Google Scholar
Liu WY, Tang Q, Zhang Q, Hu CP, Huang JB, Sheng FF, Liu YL, Zhou M, Lai WJ, Li GB, Zhang R (2019) Lycorine induces mitochondria-dependent apoptosis in hepatoblastoma HepG2 cells through ROCK1 activation. Front Pharmacol 10:651
Article CAS PubMed PubMed Central Google Scholar
Mendoza CA, Yamaoka S, Tsuda Y, Matsuno K, Weisend CM, Ebihara H (2021) The NF-kappaB inhibitor, SC75741, is a novel antiviral against emerging tick-borne bandaviruses. Antiviral Res 185:104993
Article CAS PubMed Google Scholar
Nasser MI, Masood M, Wei W, Li X, Zhou Y, Liu B, Li J, Li X (2017) Cordycepin induces apoptosis in SGC7901 cells through mitochondrial extrinsic phosphorylation of PI3K/Akt by generating ROS. Int J Oncol 50:911–919
Article CAS PubMed Google Scholar
Puliyappadamba VT, Hatanpaa KJ, Chakraborty S, Habib AA (2014) The role of NF-kappaB in the pathogenesis of glioma. Mol Cell Oncol 1:e963478
Article PubMed PubMed Central Google Scholar
Roy M, Liang L, Xiao X, Peng Y, Luo Y, Zhou W, Zhang J, Qiu L, Zhang S, Liu F, Ye M, Zhou W, Liu J (2016) Lycorine downregulates HMGB1 to Inhibit autophagy and enhances bortezomib activity in multiple myeloma. Theranostics 6:2209–2224
Article CAS PubMed PubMed Central Google Scholar
Schimmel K, Jung M, Foinquinos A, Jose GS, Beaumont J, Bock K, Grote-Levi L, Xiao K, Bar C, Pfanne A, Just A, Zimmer K, Ngoy S, Lopez B, Ravassa S, Samolovac S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F, Kreutzer FP, Kenneweg F, Leonardy J, Hobuss L, Santer L, Do QT, Geffers R, Braesen JH, Schmitz J, Brandenberger C, Muller DN, Wilck N, Kaever V, Bahre H, Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J, Gonzalez A, Thum T (2020) Natural compound library screening identifies new molecules for the treatment of cardiac fibrosis and diastolic dysfunction. Circulation 141:751–767
Article CAS PubMed PubMed Central Google Scholar
Shen J, Zhang T, Cheng Z, Zhu N, Wang H, Lin L, Wang Z, Yi H, Hu M (2018) Lycorine inhibits glioblastoma multiforme growth through EGFR suppression. J Exp Clin Cancer Res 37:157
Article PubMed PubMed Central Google Scholar
Silginer M, Weller M, Stupp R, Roth P (2017) Biological activity of tumor-treating fields in preclinical glioma models. Cell Death Dis 8:e2753
Article CAS PubMed PubMed Central Google Scholar
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO, R. European Organisation for, T. Treatment of Cancer Brain, G. Radiotherapy, G. National Cancer Institute of Canada Clinical Trials (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–96
Article CAS PubMed Google Scholar
Volmar MNM, Cheng J, Alenezi H, Richter S, Haug A, Hassan Z, Goldberg M, Li Y, Hou M, Herold-Mende C, Maire CL, Lamszus K, Fluh C, Held-Feindt J, Gargiulo G, Topping GJ, Schilling F, Saur D, Schneider G, Synowitz M, Schick JA, Kalin RE, Glass R (2021) Cannabidiol converts NF-kappaB into a tumor suppressor in glioblastoma with defined antioxidative properties. Neuro Oncol 23:1898–1910
Article CAS PubMed PubMed Central Google Scholar
Wang Y, Qi H, Liu Y, Duan C, Liu X, Xia T, Chen D, Piao HL, Liu HX (2021) The double-edged roles of ROS in cancer prevention and therapy. Theranostics 11:4839–4857
Article CAS PubMed PubMed Central Google Scholar
Wu S, Qiu Y, Shao Y, Yin S, Wang R, Pang X, Ma J, Zhang C, Wu B, Koo S, Han L, Zhang Y, Gao X, Wang T, Yu H (2018) Lycorine Displays potent antitumor efficacy in colon carcinoma by targeting STAT3. Front Pharmacol 9:881
Article PubMed PubMed Central Google Scholar
Zhang SY, Li XB, Hou SG, Sun Y, Shi YR, Lin SS (2016) Cedrol induces autophagy and apoptotic cell death in A549 non-small cell lung carcinoma cells through the P13K/Akt signaling pathway, the loss of mitochondrial transmembrane potential and the generation of ROS. Int J Mol Med 38:291–299
Article CAS PubMed Google Scholar
Zhang P, Zhang M, Yu D, Liu W, Hu L, Zhang B, Zhou Q, Cao Z (2019) Lycorine inhibits melanoma cell migration and metastasis mainly through reducing intracellular levels of beta-catenin and matrix metallopeptidase 9. J Cell Physiol 234:10566–10575
Article CAS PubMed Google Scholar
Zhang W, Yang J, Chen Y, Xue R, Mao Z, Lu W, Jiang Y (2021) Lycorine hydrochloride suppresses stress-induced premature cellular senescence by stabilizing the genome of human cells. Aging Cell 20:e13307
留言 (0)