Idiopathic pulmonary fibrosis
Amino acid metabolism
Lipid metabolism
Carbohydrate metabolism
TCA cycle
Therapeutic targets
AbbreviationsADMAAsymmetric dimethylarginine
AMPKAMP- activated protein kinase
ATFActivating transcription factor
ATIAlveolar epithelial type I cells
ATIIAlveolar epithelial type II cells
ATPAdenosine triphosphate
BALBronchioalveolar lavage
BALFBronchioalveolar lavage fluid
CADCis-aconitate decarboxylase
CebpbCCAAT enhancer binding protein
DDAHDimethylarginine dimethylaminohydrolase
Erb2Receptor tyrosine kinase 2
FgfFibroblast growth factor
H4K16AcHistone H4 lysine16 acetylation
hBMSCsHuman bone marrow stromal cells
HDAC8Histone deacetylase 8
HIF-1αHypoxia inducible factor-1 alpha
IMInterstitial macrophage
IPFIdiopathic pulmonary fibrosis
mTORMammalian target of rapamycin
NADNicotinamide adenine dinucleotide
NETsNeutrophil extracellular traps
PDGFRPlatelet-derived growth factor receptor
PFSProgression free survival
PGDFPlatelet derived growth factor
PHGDHPhosphoglycerate dehydrogenase
PI3KPhosphoinositide kinase 3
PPARPeroxisome proliferator-activated receptor
ROSReactive oxygen species
S1PSphingosine 1-phosphate
SDHSuccinate dehydrogenase
SHMT2Hydroxymethyltransferase
SMADSuppressor of mothers against decapentaplegic
SUCNR1Succinate receptor 1
TAZWW domain containing transcription regulator 1
TGF-βTransforming growth factor-beta
Timp2Tissue inhibitor of metalloproteases 2
VEGFVascular endothelial growth factor
XIAPX-linked inhibitor of apoptosis
YAPYes associated protein
α-SMAalpha smooth muscle actin
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