Musculoskeletal crosstalk in chronic obstructive pulmonary disease and comorbidities: Emerging roles and therapeutic potentials

Keywords

Exacerbations

Macrophage polarisation

Musculoskeletal-lung axis

Antioxidant

Precision medicine

Pulmonary rehabilitation

AbbreviationsACE

Angiotensin converting enzyme

AECOPD

Acute exacerbation of chronic obstructive pulmonary disease

BMP

Bone morphogenic protein

COPD

Chronic obstructive pulmonary disease

DMD

Duchenne muscular dystrophy

FEV1

Forced expiratory volume in the first second

GOLD

Global initiative for chronic obstructive lung disease

HSC

Hematopoietic stem cell

IGF-1

Insulin-like growth factor 1

MAFbx

Muscle atrophy F-box

MMP

Matrix metalloproteinase

MyoD

Myoblast determination protein 1

RANK

Receptor activator for nuclear factor-κB

RANKL

Receptor activator for nuclear factor-κB ligand

RNS

Reactive nitrogen species

ROS

Reactive oxygen species

TGFβ

Transforming growth factor β

TNF-α

Tumour necrosis factor α

Data availability

No data was used for the research described in the article.

© 2024 The Authors. Published by Elsevier Inc.

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