Antibiotics in the Treatment of Uncomplicated Cystitis: A Google Trends Analysis

Değer M.D.Madendere S.b· Öztekin Ç.V.c

Author affiliations

aDepartment of Urology, Edirne Sultan 1st Murat State Hospital, Edirne, Turkey
bDepartment of Urology, Çorlu State Hospital, Çorlu, Turkey
cDepartment of Urology, Near East University, Nicosia, Cyprus

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Article / Publication Details

Received: October 15, 2022
Accepted: January 04, 2023
Published online: April 20, 2023

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 2

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: https://www.karger.com/UIN

Abstract

Introduction: Using Google Trends (GT) data, the trend variations for the most common antibiotics used to treat uncomplicated cystitis were analyzed by time and region since 2004. Methods: GT was used to create a “line-graph” that shows how interest in a topic in certain locations has grown or decreased over time. The relative search volume, which is displayed on a scale of 0–100, was used to index the search values for specific phrases. Nitrofurantoin (NFN), fosfomycin (FOS), trimethoprim (TMP), pivmecillinam (PIV), and cefadroxil are among the antibiotics recommended by the European Association of Urology (EAU) and the American Urological Association for the treatment of uncomplicated cystitis. Using the “global” inquiry category, the data was searched “worldwide” from 1 February 2004 to 31 December 2021. Results: In the regression analysis, all antibiotics exhibited positive trends (p < 0.05). With a steady rise in popularity, NFN is the most popular antibiotic today. Search trend for cefadroxil stayed nearly stable until 2012, the rate of rise in the last 10 years increased, and cefadroxil is the second most popular antibiotic. In the previous 5 years, there was a decline in interest in TMP. In recent years, there was an increase in the trends for FOS and PIV. Conclusion: Clinicians and patients all around the world increasingly use the web to search for antibiotic therapies for uncomplicated cystitis. Antibiotics used to treat uncomplicated cystitis have various trends in different continents throughout the world. The web trends seem to be compatible with daily use.

© 2023 S. Karger AG, Basel

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Received: October 15, 2022
Accepted: January 04, 2023
Published online: April 20, 2023

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 2

ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)

For additional information: https://www.karger.com/UIN

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