Currently, 1 in 44 children receive an autism diagnosis by the age of 8 years in the United States1; despite improvements in recognition of autism, autistic people still have poor long-term outcomes regarding their health and health care. Overall, autistic people are dying much younger than expected,2,3 with several studies now suggesting that autistic people are, on average, dying 12 to 30 years younger than others.3 Unfortunately, risk of dying by suicide is also elevated among autistic people,2-4 with as many as 1 in 3 reporting a previous suicide attempt.4 However, the growing literature on premature mortality also points to physical health problems that are currently underresearched and underexplored.2,3 In particular, there is a paucity of research on the chronic physical health problems among autistic people as they age, with only a handful of studies assessing chronic health burden among those older than 35 years. A new study published in this issue of JAMA Pediatrics by Dhanasekara and colleagues5 provides important context for clinicians across specialties, as all clinicians will have autistic patients.1