Visseren F.L.J. MacH F. Smulders Y.M. et al.

2021 ESC guidelines on cardiovascular disease prevention in clinical practice.

Eur Heart J. 2021; 42: 3227-3337View in Article Google ScholarKnuuti J. Saraste A. Capodanno D. et al.

2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes. The Task Force for the Diagnosis and Management of Chronic Coronary Syndromes of the European Society of Cardiology (ESC).

Eur Hear J. 2020; 41: 407-477View in Article Google ScholarVerberne H.J. Acampa W. Anagnostopoulos C. et al.

EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision.

Eur J Nucl Med Mol Imaging. 2015; 42: 1929-1940View in Article Google ScholarDanad I. Raijmakers P.G. Driessen R.S. et al.

Comparison of coronary CT angiography, SPECT, PET, and hybrid imaging for diagnosis of ischemic heart disease determined by fractional flow reserve.

JAMA Cardiol. 2017; 2: 1100-1110View in Article Google Scholar

National Institute for Health and Clinical Excellence. Chest pain of recent onset: assessment and diagnosis of recent onset chest pain or discomfort of suspected cardiac origin. CG95. London: National Institute for Health and Clinical Excellence; 2010. Last Updated 2016. https://www.nice.org.uk/guidance/CG95. Accessed February 2023.

View in Article Google ScholarGulati M. Levy P.D. Mukherjee D. et al.

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guideline for the evaluation and diagnosis of chest pain: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

JACC (J Am Coll Cardiol). 2021; 78: 221View in Article Google ScholarHerscovici R. Sedlak T. Wei J. et al.

Ischemia and no obstructive coronary artery disease (INOCA): what is the risk?.

J Am Heart Assoc. 2018; 7: e008868View in Article Google ScholarGimelli A. Liga R. Duce V. et al.

Accuracy of myocardial perfusion imaging in detecting multivessel coronary artery disease: a cardiac CZT study.

J Nucl Cardiol. 2017; 24: 687-695View in Article Google ScholarZavadovsky K.V. Mochula A.V. Boshchenko A.A. et al.

Absolute myocardial blood flows derived by dynamic CZT scan vs invasive fractional flow reserve: correlation and accuracy.

J Nucl Cardiol. 2021; 28: 249-259View in Article Google ScholarAcampa W. Assante R. Mannarino T. et al.

Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease.

Eur J Nucl Med Mol Imaging. 2020; 47: 1705-1712View in Article Google ScholarValenta I. Dilsizian V. Quercioli A. et al.

Quantitative PET/CT measures of myocardial flow reserve and atherosclerosis for cardiac risk assessment and predicting adverse patient outcomes.

Curr Cardiol Rep. 2013; 15: 344View in Article Google ScholarHerzog B.A. Husmann L. Valenta I. et al.

Long-term prognostic value of 13N-ammonia myocardial perfusion positron emission tomography. Added value of coronary flow reserve.

J Am Coll Cardiol. 2009; 54: 150-156View in Article Google ScholarMurthy V.L. Naya M. Foster C.R. et al.

Improved cardiac risk assessment with noninvasive measures of coronary flow reserve.

Circulation. 2011; 124: 2215View in Article Google ScholarZiadi M.C. DeKemp R.A. Williams K. et al.

Does quantification of myocardial flow reserve using rubidium-82 positron emission tomography facilitate detection of multivessel coronary artery disease?.

J Nucl Cardiol. 2012; 19: 670-768View in Article Google ScholarFiechter M. Ghadri J.R. Gebhard C. et al.

Diagnostic value of 13N-ammonia myocardial perfusion PET: added value of myocardial flow reserve.

J Nucl Med. 2012; 53: 1230-1231View in Article Google ScholarWells R.G. Timmins R. Klein R. et al.

Dynamic SPECT measurement of absolute myocardial blood flow in a porcine model.

J Nucl Med. 2014; 55: 1685-1691View in Article Google ScholarAgostini D. Roule V. Nganoa C. et al.

First validation of myocardial flow reserve assessed by dynamic 99mTc-sestamibi CZT-SPECT camera: head to head comparison with 15O-water PET and fractional flow reserve in patients with suspected coronary artery disease. The WATERDAY study.

Eur J Nucl Med Mol Imaging. 2018; 45 (Available at:): 1079-1090http://link.springer.com/10.1007/s00259-018-3958-7View in Article Google ScholarLiga R. Neglia D. Kusch A. et al.

Prognostic role of dynamic CZT imaging in CAD patients: interaction between absolute flow and CAD burden.

JACC (J Am Coll Cardiol): Cardiovascular Imaging. 2022; 15: 540-542View in Article Google ScholarNeglia D. Liga R. Caselli C. et al.

Anatomical and functional coronary imaging to predict long-term outcome in patients with suspected coronary artery disease: the EVINCI-outcome study.

Eur Heart J Cardiovasc Imaging. 2020; 21: 1273-1282View in Article Google ScholarTaqueti V.R. Shaw L.J. Cook N.R. et al.

Excess cardiovascular risk in women relative to men referred for coronary angiography is associated with severely impaired coronary flow reserve, not obstructive disease.

Circulation. 2017; 135: 566-657View in Article Google ScholarBetancur J. Otaki Y. Motwani M. et al.

Prognostic value of combined clinical and myocardial perfusion imaging data using machine learning.

JACC Cardiovasc Imaging. 2018; 11: 1000-1009View in Article Google ScholarRios R. Miller R.J.H. Hu L.H. et al.

Determining a minimum set of variables for machine learning cardiovascular event prediction: results from REFINE SPECT registry.

Cardiovasc Res. 2022; 118: 2152-2164View in Article Google ScholarGehi A.K. Ali S. Na B. et al.

Inducible ischemia and the risk of recurrent cardiovascular events in outpatients with stable coronary heart disease: the heart and soul study.

Arch Intern Med. 2008; 168: 1423-1428View in Article Google ScholarHachamovitch R. Rozanski A. Shaw L.J. et al.

Impact of ischaemia and scar on the therapeutic benefit derived from myocardial revascularization vs. medical therapy among patients undergoing stress-rest myocardial perfusion scintigraphy.

Eur Heart J. 2011; 32: 1012-1024View in Article Google ScholarDoenst T. Haverich A. Serruys P. et al.

PCI and CABG for treating stable coronary artery disease.

J Am Coll Cardiol. 2019; 73: 964-976View in Article Google ScholarBoden W.E. O’Rourke R.A. Teo K.K. et al.

Optimal medical therapy with or without PCI for stable coronary disease.

N Engl J Med. 2007; 356: 1503-1511View in Article Google ScholarAl-Lamee R. Thompson D. Dehbi H.M. et al.

Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial.

Lancet. 2018; 391: 31-40View in Article Google ScholarCleland J.G.F. Calvert M. Freemantle N. et al.

The heart failure revascularisation trial (HEART).

Eur J Heart Fail. 2011; 391: 31-40View in Article Google ScholarStergiopoulos K. Boden W.E. Hartigan P. et al.

Percutaneous coronary intervention outcomes in patients with stable obstructive coronary artery disease and myocardial ischemia.

JAMA Intern Med. 2014; 174: 232-240View in Article Google ScholarMiller R.J.H. Bonow R.O. Gransar H. et al.

Percutaneous or surgical revascularization is associated with survival benefit in stable coronary artery disease.

Eur Heart J Cardiovasc Imaging. 2020; 21: 961-997View in Article Google ScholarHochman J.S. Reynolds H.R. Bangalore S. et al.

Baseline characteristics and risk profiles of participants in the ISCHEMIA randomized clinical trial.

JAMA Cardiol. 2019; 4: 273-286View in Article Google ScholarMaron D.J. Hochman J.S. Reynolds H.R. et al.

Initial invasive or conservative strategy for stable coronary disease.

N Engl J Med. 2020; 382: 1395-1404View in Article Google ScholarInvestigators S.-H.

Coronary CT angiography and 5-year risk of myocardial infarction.

N Engl J Med. 2018; 379: 924-933View in Article Google ScholarLiga R. Neglia D. Cavaleri S. et al.

Prognostic impact of patients’ management based on anatomic/functional phenotype: a study in patients with chronic coronary syndromes.

J Nucl Cardiol. 2022; https://doi.org/10.1007/s12350-022-03070-wView in Article Google ScholarDe Bruyne B. Fearon W.F. Pijls N.H.J. et al.

Fractional flow reserve–guided PCI for stable coronary artery disease.

N Engl J Med. 2014; 371: 12View in Article Google ScholarLiga R. Vontobel J. Rovai D. et al.

Multicentre multi-device hybrid imaging study of coronary artery disease: results from the EValuation of INtegrated Cardiac Imaging for the Detection and Characterization of Ischaemic Heart Disease (EVINCI) hybrid imaging population.

Eur Heart J Cardiovasc Imaging. 2016; 17: 951View in Article Google ScholarWerner R.A. Rischpler C. Onthank D. et al.

Retention kinetics of the 18F-labeled sympathetic nerve PET tracer LMI1195: comparison with 11C-hydroxyephedrine and 123I-MIBG.

J Nucl Med. 2015; 56: 1429-1433View in Article Google ScholarJacobson A.F. Senior R. Cerqueira M.D. et al.

Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView myocardial imaging for risk evaluation in heart failure) study.

J Am Coll Cardiol. 2010; 55: 2212-2222View in Article Google ScholarGimelli A. Liga R. Giorgetti A. et al.

Assessment of myocardial adrenergic innervation with a solid-state dedicated cardiac cadmium-zinc-telluride camera: first clinical experience.

Eur Heart J Cardiovasc Imaging. 2014; 15: 575-585View in Article Google ScholarNakajima K. Nakata T. Yamada T. et al.

A prediction model for 5-year cardiac mortality in patients with chronic heart failure using 123I-metaiodobenzylguanidine imaging.

Eur J Nucl Med Mol Imaging. 2014; 41: 1673-1682View in Article Google ScholarKøber L. Thune J.J. Nielsen J.C. et al.

Defibrillator implantation in patients with nonischemic systolic heart failure.

N Engl J Med. 2016; 375: 1221-1223View in Article Google ScholarMoreira R.I. Abreu A. Portugal G. et al.

Prognostic effect and modulation of cardiac sympathetic function in heart failure patients treated with cardiac resynchronization therapy.

J Nucl Cardiol. 2020; 27: 283-329View in Article Google ScholarGimelli A. Liga R. Menichetti F. et al.

Interactions between myocardial sympathetic denervation and left ventricular mechanical dyssynchrony: a CZT analysis.

J Nucl Cardiol. 2019; 26: 509-518View in Article Google ScholarJacobson A.F. Senior R. Cerqueira M.D. et al.

Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView myocardial imaging for risk evaluation in heart failure) study.

J Am Coll Cardiol. 2010; 55: 2212-2221View in Article Google ScholarTravin M.I. Henzlova M.J. van Eck-Smit B.L.F. et al.

Assessment of 123I-mIBG and 99mTc-tetrofosmin single-photon emission computed tomographic images for the prediction of arrhythmic events in patients with ischemic heart failure: intermediate severity innervation defects are associated with higher arrhythm.

J Nucl Cardiol. 2017; 24: 377-391View in Article Google ScholarSasano T. Abraham M.R. Chang K.C. et al.

Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction.

J Am Coll Cardiol. 2008; 51: 2266-2267View in Article Google ScholarIrkle A. Vesey A.T. Lewis D.Y. et al.

Identifying active vascular microcalcification by 18F-sodium fluoride positron emission tomography.

Nat Commun. 2015; 6: 7495View in Article Google Scholar