Problem-based learning encourages students to deepen their understanding of a concept by working through a real-world example of course content. Case studies represent a form of problem-based learning that engage students in realistic scenarios to achieve a deeper understanding of concepts. Case studies have been shown to facilitate the learning of challenging subject matter. We hypothesized that the use of a case study would help students better learn the topic of genomic imprinting, an abstract phenomenon in molecular biology and genetics. We wrote an interrupted case study which focused on genomic imprinting. The case study consists of three short popular news articles which relate to genomic imprinting. Each article is followed by a set of 2-4 questions. Students read each article and discuss its associated questions in small groups, then with the entire class, before moving on to the next article. We deployed the case study in an intermediate-level molecular biology course at a small, liberal-arts university. We assessed student learning and attitudes towards the case study (50 pre/post matched pairs). In four true/false assessment questions, our results showed that students' performance on the assessment after the case study was significantly higher than their performance before the case study. Students also self-reported increased knowledge on concepts related to genomic imprinting. Finally, students were likely to agree that the case study was beneficial to their learning and was an enjoyable classroom activity. We conclude that the case study is an effective way to instruct students about the topic of genomic imprinting.