Ahluwalia V, Wade JB, Moeller FG, White MB, Unser AB, Gavis EA, Sterling RK, Stravitz RT, Sanyal AJ, Siddiqui MS, Puri P, Luketic V, Heuman DM, Fuchs M, Matherly S, Bajaj JS (2015) The etiology of cirrhosis is a strong determinant of brain reserve: a multimodal magnetic resonance imaging study. Liver Transpl 21(9):1123–1132. https://doi.org/10.1002/lt.24163

Article  PubMed  PubMed Central  Google Scholar 

Ahluwalia V, Betrapally NS, Hylemon PB, White MB, Gillevet PM, Unser AB, Fagan A, Daita K, Heuman DM, Zhou H, Sikaroodi M, Bajaj JS (2016) Impaired gut–liver-brain axis in patients with cirrhosis. Sci Rep 26(6):26800. https://doi.org/10.1038/srep26800

Article  CAS  Google Scholar 

Ahmad A, Shah SA, Badshah H, Kim MJ, Ali T, Yoon GH, Kim TH, Abid NB, Rehman SU, Khan S, Kim MO (2016) Neuroprotection by vitamin C against ethanol-induced neuroinflammation associated neurodegeneration in the developing rat brain. CNS Neurol Disord Drug Targets 15(3):360–370. https://doi.org/10.2174/1871527315666151110130139

Article  CAS  PubMed  Google Scholar 

Akers KG, Martinez-Canabal A, Restivo L, Yiu AP, De Cristofaro A, Hsiang HL, Wheeler AL, Guskjolen A, Niibori Y, Shoji H, Ohira K, Richards BA, Miyakawa T, Josselyn SA, Frankland PW (2014) Hippocampal neurogenesis regulates forgetting during adulthood and infancy. Science 344(6184):598–602. https://doi.org/10.1126/science.1248903

Article  CAS  PubMed  Google Scholar 

Alfonso-Loeches S, Pascual-Lucas M, Blanco AM, Sanchez-Vera I, Guerri C (2010) Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage. J Neurosci 30(24):8285–8295. https://doi.org/10.1523/JNEUROSCI.0976-10.2010

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alfonso-Loeches S, Ureña-Peralta JR, Morillo-Bargues MJ, Oliver-De La Cruz J, Guerri C (2014) Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells. Front Cell Neurosci 8:216. https://doi.org/10.3389/fncel.2014.00216

Article  PubMed  PubMed Central  Google Scholar 

Ali T, Rehman SU, Shah FA, Kim MO (2018) Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain. J Neuroinflammation 15(1):119. https://doi.org/10.1186/s12974-018-1157-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Altman J, Das GD (1965) Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 124(3):319–335. https://doi.org/10.1002/cne.901240303

Article  CAS  PubMed  Google Scholar 

Ambhore N, Antony S, Mali J, Kanhed A, Bhalerao A, Bhojraj S (2012) Pharmacological and biochemical interventions of cigarette smoke, alcohol, and sexual mating frequency on idiopathic rat model of Parkinson’s disease. J Young Pharm 4(3):177–183. https://doi.org/10.4103/0975-1483.100026

Article  CAS  PubMed  PubMed Central  Google Scholar 

Amin FU, Shah SA, Kim MO (2016) Glycine inhibits ethanol-induced oxidative stress, neuroinflammation and apoptotic neurodegeneration in postnatal rat brain. Neurochem Int 96:1–12. https://doi.org/10.1016/j.neuint.2016.04.001

Article  CAS  PubMed  Google Scholar 

Anand SK, Mondal AC (2017) Cellular and molecular attributes of neural stem cell niches in adult zebrafish brain. Dev Neurobiol 77(10):1188–1205. https://doi.org/10.1002/dneu.2250

Article  PubMed  Google Scholar 

Arruda-Carvalho M, Sakaguchi M, Akers KG, Josselyn SA, Frankland PW (2011) Posttraining ablation of adult-generated neurons degrades previously acquired memories. J Neurosci 31(42):15113–15127. https://doi.org/10.1523/JNEUROSCI.3432-11.2011

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bajaj JS (2019) Alcohol, liver disease and the gut microbiota. Nat Rev Gastroenterol Hepatol 16(4):235–246. https://doi.org/10.1038/s41575-018-0099-1

Article  PubMed  Google Scholar 

Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, Heuman DM, Smith S, Sikaroodi M, Gillevet PM (2012) Linkage of gut microbiome with cognition in hepatic encephalopathy. Am J Physiol Gastrointest Liver Physiol 302(1):G168–G175. https://doi.org/10.1152/ajpgi.00190.2011

Article  CAS  PubMed  Google Scholar 

Banan A, Keshavarzian A, Zhang L, Shaikh M, Forsyth CB, Tang Y, Fields JZ (2007) NF-kappaB activation as a key mechanism in ethanol-induced disruption of the F-actin cytoskeleton and monolayer barrier integrity in intestinal epithelium. Alcohol 41(6):447–460. https://doi.org/10.1016/j.alcohol.2007.07.003

Article  CAS  PubMed  Google Scholar 

Banks WA, Gray AM, Erickson MA, Salameh TS, Damodarasamy M, Sheibani N, Meabon JS, Wing EE, Morofuji Y, Cook DG, Reed MJ (2015) Lipopolysaccharide-induced blood–brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit. J Neuroinflamm 25(12):223. https://doi.org/10.1186/s12974-015-0434-1

Article  CAS  Google Scholar 

Baradaran Z, Vakilian A, Zare M, Hashemzehi M, Hosseini M, Dinpanah H, Beheshti F (2021) Metformin improved memory impairment caused by chronic ethanol consumption during adolescent to adult period of rats: role of oxidative stress and neuroinflammation. Behav Brain Res 6(411):113399. https://doi.org/10.1016/j.bbr.2021.113399

Article  CAS  Google Scholar 

Battista D, Ferrari CC, Gage FH, Pitossi FJ (2006) Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus. Eur J Neurosci 23(1):83–93. https://doi.org/10.1111/j.1460-9568.2005.0453

Article  PubMed  Google Scholar 

Belmadani A, Tran PB, Ren D, Miller RJ (2006) Chemokines regulate the migration of neural progenitors to sites of neuroinflammation. J Neurosci 26(12):3182–3191. https://doi.org/10.1523/JNEUROSCI.0156-06.2006

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ben-Hur T, Einstein O, Mizrachi-Kol R, Ben-Menachem O, Reinhartz E, Karussis D, Abramsky O (2003a) Transplanted multipotential neural precursor cells migrate into the inflamed white matter in response to experimental autoimmune encephalomyelitis. Glia 41(1):73–80. https://doi.org/10.1002/glia.10159

Article  PubMed  Google Scholar 

Ben-Hur T, Ben-Menachem O, Furer V, Einstein O, Mizrachi-Kol R, Grigoriadis N (2003b) Effects of proinflammatory cytokines on the growth, fate, and motility of multipotential neural precursor cells. Mol Cell Neurosci 24(3):623–631. https://doi.org/10.1016/s1044-7431(03)00218-5

Article  CAS  PubMed  Google Scholar 

Bergmann O, Liebl J, Bernard S, Alkass K, Yeung MS, Steier P, Kutschera W, Johnson L, Landén M, Druid H, Spalding KL, Frisén J (2012) The age of olfactory bulb neurons in humans. Neuron 74(4):634–639. https://doi.org/10.1016/j.neuron.2012.03.030

Article  CAS  PubMed  Google Scholar 

Bertola A, Mathews S, Ki SH, Wang H, Gao B (2013) Mouse model of chronic and binge ethanol feeding (the NIAAA model). Nat Protoc 8(3):627–637. https://doi.org/10.1038/nprot.2013.032

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bönsch D, Greifenberg V, Bayerlein K, Biermann T, Reulbach U, Hillemacher T, Kornhuber J, Bleich S (2005) Alpha-synuclein protein levels are increased in alcoholic patients and are linked to craving. Alcohol Clin Exp Res 29(5):763–765. https://doi.org/10.1097/01.alc.0000164360.43907.24

Article  PubMed  Google Scholar 

Boyadjieva NI, Sarkar DK (2013) Microglia play a role in ethanol-induced oxidative stress and apoptosis in developing hypothalamic neurons. Alcohol Clin Exp Res 37(2):252–262. https://doi.org/10.1111/j.1530-0277.2012.01889.x

Article  CAS  PubMed  Google Scholar 

Bühler M, Mann K (2011) Alcohol and the human brain: a systematic review of different neuroimaging methods. Alcohol Clin Exp Res 35(10):1771–1793. https://doi.org/10.1111/j.1530-0277.2011.01540.x

Article  CAS  PubMed  Google Scholar 

Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M (2006) Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci 31(1):149–160. https://doi.org/10.1016/j.mcn.2005.10.006

Article  CAS  PubMed  Google Scholar 

Cameron HA, McKay RD (2001) Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J Comp Neurol 435(4):406–417. https://doi.org/10.1002/cne.1040

Article  CAS  PubMed  Google Scholar 

Cannon AR, Hammer AM, Choudhry MA (2018) Alcohol, inflammation, and depression: the gut–brain axis. Inflammation and immunity in depression. Academic Press, Boca Raton, pp 509–524

Book  Google Scholar 

Chaturvedi A, Rao G, Praharaj SK, Guruprasad KP, Pais V (2020) Reduced serum levels of cluster of differentiation 200 in alcohol-dependent patients. Alcohol Alcohol 55(4):391–394. https://doi.org/10.1093/alcalc/agaa033

Article  CAS  PubMed  Google Scholar 

Cippitelli A, Domi E, Ubaldi M, Douglas JC, Li HW, Demopulos G, Gaitanaris G, Roberto M, Drew PD, Kane CJM, Ciccocioppo R (2017) Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone. Brain Behav Immun 64:320–329. https://doi.org/10.1016/j.bbi.2017.02.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Clelland CD, Choi M, Romberg C, Clemenson GD Jr, Fragniere A, Tyers P, Jessberger S, Saksida LM, Barker RA, Gage FH, Bussey TJ (2009) A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325(5937):210–213. https://doi.org/10.1126/science.1173215

Article  CAS  PubMed  PubMed Central  Google Scholar 

Coleman LG Jr, Crews FT (2018) Innate immune signaling and alcohol use disorders. Handb Exp Pharmacol 248:369–396. https://doi.org/10.1007/164_2018_92

Article  CAS  PubMed  PubMed Central  Google Scholar