Andreasen N. Symptoms, signs, and diagnosis of schizophrenia. Lancet. 1995;346:477–81.
Article PubMed CAS Google Scholar
Ross CA, Margolis RL, Reading SA, Pletnikov M, Coyle JT. Neurobiology of schizophrenia. Neuron. 2006;52:139–53.
Article PubMed CAS Google Scholar
Birnbaum R, Weinberger DR. Genetic insights into the neurodevelopmental origins of schizophrenia. Nat Rev Neurosci. 2017;18:727–40.
Article PubMed CAS Google Scholar
Kochunov P, Hong LE. Neurodevelopmental and neurodegenerative models of schizophrenia: white matter at the center stage. Schizophrenia Bull. 2014;40:721–8.
Tau GZ, Peterson BS. Normal development of brain circuits. Neuropsychopharmacology. 2010;35:147–68.
Mäki P, Veijola J, Jones PB, Murray GK, Koponen H, Tienari P, et al. Predictors of schizophrenia—a review. Br Med Bull. 2005;73:1–15.
Consortium, S.W.G.O.T.P.G. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511:421–7.
Ripke S, O’Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet. 2013;45:1150.
Article PubMed PubMed Central CAS Google Scholar
Ikeda M, Takahashi A, Kamatani Y, Okahisa Y, Kunugi H, Mori N, et al. A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder. Mol psychiatry. 2018;23:639–47.
Article PubMed CAS Google Scholar
Sleiman P, Wang D, Glessner J, Hadley D, Gur RE, Cohen N, et al. GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia/Bipolar susceptibility locus. Sci Rep. 2013;3:1–5.
Jaffe AE, Gao Y, Deep-Soboslay A, Tao R, Hyde TM, Weinberger DR, et al. Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat Neurosci. 2016;19:40–47.
Article PubMed CAS Google Scholar
Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM, et al. Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nat Neurosci. 2016;19:48–54.
Article PubMed CAS Google Scholar
Ganapathiraju MK, Thahir M, Handen A, Sarkar SN, Sweet RA, Nimgaonkar VL, et al. Schizophrenia interactome with 504 novel protein–protein interactions. NPJ schizophrenia. 2016;2:1–10.
Avram S, Mernea M, Mihailescu DF, Seiman CD, Seiman DD, Putz MV. Mitotic checkpoint proteins Mad1 and Mad2-structural and functional relationship with implication in genetic diseases. Curr computer-aided drug Des. 2014;10:168–81.
London N, Biggins S. Signalling dynamics in the spindle checkpoint response. Nat Rev Mol cell Biol. 2014;15:736–48.
Article PubMed PubMed Central CAS Google Scholar
Lischetti T, Nilsson J. Regulation of mitotic progression by the spindle assembly checkpoint. Mol Cell Oncol. 2015;2:e970484.
Article PubMed PubMed Central Google Scholar
Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol cell Biol. 2007;8:379–93.
Article PubMed CAS Google Scholar
Akera T, Goto Y, Sato M, Yamamoto M, Watanabe Y. Mad1 promotes chromosome congression by anchoring a kinesin motor to the kinetochore. Nat cell Biol. 2015;17:1124–33.
Article PubMed CAS Google Scholar
Tsukasaki K, Miller CW, Greenspun E, Eshaghian S, Kawabata H, Fujimoto T, et al. Mutations in the mitotic check point gene, MAD1L1, in human cancers. Oncogene. 2001;20:3301–5.
Article PubMed CAS Google Scholar
Sun Q, Zhang X, Liu T, Liu X, Geng J, He X, et al. Increased expression of mitotic arrest deficient-like 1 (MAD1L1) is associated with poor prognosis and insensitive to Taxol treatment in breast cancer. Breast cancer Res Treat. 2013;140:323–30.
Article PubMed CAS Google Scholar
Zhou H, Wang T, Zheng T, Teng J, Chen J. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1–Mad2. Nat Commun. 2016;7:1–13.
Wan J, Zhu F, Zasadil LM, Yu J, Wang L, Johnson A, et al. A Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration. Curr Biol. 2014;24:2687–92.
Article PubMed PubMed Central CAS Google Scholar
Yanagida M, Miyoshi R, Toyokuni R, Zhu Y, Murakami F. Dynamics of the leading process, nucleus, and Golgi apparatus of migrating cortical interneurons in living mouse embryos. Proc Natl Acad Sci USA. 2012;109:16737–42.
Article PubMed PubMed Central CAS Google Scholar
Tsai L-H, Gleeson JG. Nucleokinesis in Neuronal Migration. Neuron. 2005;46:383–8.
Article PubMed CAS Google Scholar
Tahirovic S, Bradke F. Neuronal polarity. Cold Spring Harb Perspect Biol. 2009;1:a001644–a001644.
Article PubMed PubMed Central Google Scholar
Dillon GM, Tyler WA, Omuro KC, Kambouris J, Tyminski C, Henry S, et al. CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Neuron. 2017;93:1344–.e5.
Article PubMed PubMed Central CAS Google Scholar
Kamiya A, Kubo K-i, Tomoda T, Takaki M, Youn R, Ozeki Y, et al. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol. 2005;7:1167–78.
Mikhaylova M, Bera S, Kobler O, Frischknecht R, Kreutz MR. A Dendritic Golgi Satellite between ERGIC and Retromer. Cell Rep. 2016;14:189–99.
Article PubMed CAS Google Scholar
Horton AC, Rácz B, Monson EE, Lin AL, Weinberg RJ, Ehlers MD. Polarized Secretory Trafficking Directs Cargo for Asymmetric Dendrite Growth and Morphogenesis. Neuron. 2005;48:757–71.
Article PubMed CAS Google Scholar
Horton AC, Ehlers MD. Dual modes of endoplasmic reticulum-to-Golgi transport in dendrites revealed by live-cell imaging. J Neurosci: Off J Soc Neurosci. 2003;23:6188–99.
Lepagnol-Bestel A, Kvajo M, Karayiorgou M, Simonneau M, Gogos J. A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons. Mol Cell Neurosci. 2013;54:84–92.
Article PubMed PubMed Central CAS Google Scholar
de Anda FC, Pollarolo G, Da Silva JS, Camoletto PG, Feiguin F, Dotti CG. Centrosome localization determines neuronal polarity. Nature. 2005;436:704–8.
Suh BK, Lee S-A, Park C, Suh Y, Kim SJ, Woo Y, et al. Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150 glued. Mol brain. 2021;14:1–14.
Samuels ML, Witmer JA, Schaffner A. Statistics for the Life Sciences, 5th Edition. Pearson Education, 2014.
Pollard DA, Pollard TD, Pollard KS. Empowering statistical methods for cellular and molecular biologists. Mol Biol cell. 2019;30:1359–68.
Article PubMed PubMed Central CAS Google Scholar
Noack F, Vangelisti S, Raffl G, Carido M, Diwakar J, Chong F, et al. Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler. Nat Neurosci. 2022;25:154–67.
Article PubMed PubMed Central CAS Google Scholar
Mukhtar T, Taylor V. Untangling cortical complexity during development. J Exp Neurosci. 2018;12:1179069518759332.
Article PubMed PubMed Central Google Scholar
Zhang D, Yin S, Jiang M-X, Ma W, Hou Y, Liang C-G, et al. Cytoplasmic dynein participates in meiotic checkpoint inactivation in mouse oocytes by transporting cytoplasmic mitotic arrest-deficient (Mad) proteins from kinetochores to spindle poles. Reproduction. 2007;133:685–95.
Article PubMed CAS Google Scholar
Ju X-C, Hou Q-Q, Sheng A-L, Wu K-Y, Zhou Y, Jin Y, et al. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. Elife. 2016;5:e18197.
Article PubMed PubMed Central Google Scholar
Zhang H, Zhang L, Sun T. Cohesive regulation of neural progenitor development by microRNA miR-26, its host gene ctdsp and target gene Emx2 in the mouse embryonic cerebral cortex. Front Mol Neurosci. 2018;11:44.
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