Young NS, Calado RT, Scheinberg P (2006) Current concepts in the pathophysiology and treatment of aplastic anemia. Blood 108:2509–2519

Article  PubMed  PubMed Central  CAS  Google Scholar 

Maluf E, Hamerschlak N, Cavalcanti AB et al (2009) Incidence and risk factors of aplastic anemia in Latin American countries: the LATIN case-control study. Haematologica 94:1220–1226

Article  PubMed  PubMed Central  Google Scholar 

Vaht K, Göransson M, Carlson K et al (2017) Incidence and outcome of acquired aplastic anemia: real-world data from patients diagnosed in Sweden from 2000–2011. Haematologica 102:1683–1690

Article  PubMed  PubMed Central  Google Scholar 

Issaragrisil S, Kaufman DW, Anderson T et al (2006) The epidemiology of aplastic anemia in Thailand. Blood 107:1299–1307

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yong AS, Goh AS, Rahman M et al (1998) Epidemiology of aplastic anaemia in the state of Sabah, Malaysia. Med J Malaysia 53:59–62

PubMed  CAS  Google Scholar 

Jeong DC, Chung NG, Kang HJ et al (2011) Epidemiology and clinical long-term outcome of childhood aplastic anemia in Korea for 15 years: retrospective study of the Korean Society of Pediatric Hematology Oncology (KSPHO). J Pediatr Hematol Oncol 33:172–178

Article  PubMed  Google Scholar 

Kojima S (2017) Why is the incidence of aplastic anemia higher in Asia? Expert Rev Hematol 10:277–279

Article  PubMed  CAS  Google Scholar 

Kumar R, Kalra SP, Kumar H, Anand AC, Madan H (2001) Pancytopenia—a six year study. J Assoc Physicians India 49:1078–1081

PubMed  CAS  Google Scholar 

Mahapatra M, Singh PK, Agarwal M et al (2015) Epidemiology, clinicohematological profile and management of aplastic anemia:AIIMS Experience. J Assoc Physicians India 63:30–35

PubMed  CAS  Google Scholar 

Ahamed M, Anand M, Kumar A et al (2006) Childhood aplastic anaemia in Lucknow, India: incidence, organochlorines in the blood and review of case reports following exposure to pesticides. Clin Biochem 39:762–766

Article  PubMed  CAS  Google Scholar 

Goswami BK, Chakrabarti S, Paul PC, Pramanik R, Raha K, Das S (2009) Clinicohaematological analysis of aplastic anaemia among children of northern districts of West Bengal. J Indian Med Assoc 107:17–18

PubMed  Google Scholar 

Nair V, Sharma A, Das S, Sondhi V et al (2013) Immunosuppressive therapy in adults with aplastic anaemia: single-institution experience from India. Postgrad Med J 89:508–515

Article  PubMed  CAS  Google Scholar 

Dutta A, De R, Dolai T, Mitra P, Halder A (2019) Journal of Blood Disorders, Symptoms & Treatments. Comparative Study of Environmental Factors and Different Addictions in Aplastic Anaemia. Patients in Eastern India 2:1–8

Google Scholar 

Jain D, Kumar R, Tyagi N, Negi A, Pande A, Mahajan A, Pandey PK, Malik R, Raina V, Malik BK (2012 Nov) Etiology and survival of aplastic anemia: a study based on clinical investigation. J Clin Lab Anal 26(6):452–458. doi: https://doi.org/10.1002/jcla.21546 PMID: 23143628; PMCID: PMC6807622

Young NS, Kaufman DW (2008) The epidemiology of acquired aplastic anemia. Haematologica 93:489–492

Article  PubMed  Google Scholar 

Kapoor M, Agrawal D, Ravi S et al (2019) Missing female patients: an observational analysis of sex ratio among outpatients in a referral tertiary care public hospital in India. BMJ Open 9:e026850

Article  PubMed  PubMed Central  Google Scholar 

Luzzatto L, Risitano AM (2018) Advances in understanding the pathogenesis of acquired aplastic anaemia. Br J Haematol 182:758–777

Article  PubMed  Google Scholar 

Scheinberg P, Young NS (2012) How I treat acquired aplastic anaemia. Blood 120:1185–1196

Article  PubMed  PubMed Central  CAS  Google Scholar 

Lin FC, Karwan M, Saleh B et al (2014) IFN-γ causes aplastic anemia by altering hematopoiesis stem/progenitor cell composition and disrupting lineage differentiation. Blood 124:3699–3708

Article  PubMed  PubMed Central  CAS  Google Scholar 

Alvarado L, Huntsman HD, Cheng H, Knutson JR, Larochelle A (2017) Heterodimerization of TPO and IFNγ impairs human hematopoietic stem/progenitor cell signaling and survival in chronic inflammation. Blood 130:4

Google Scholar 

Townsley DM, Scheinberg P, Winkler T et al (2017) Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia. N Engl J Med 376:1540–1550

Article  PubMed  PubMed Central  CAS  Google Scholar 

Killick SB, Bown N, Cavenagh J, Dokal I, Foukaneli T, Hill A et al (2016) The British Society for Standards in Haematology. Guidelines for the diagnosis and management of adult aplastic anaemia. Br J Haematol 172:187–207

Article  PubMed  Google Scholar 

Rovo A, Tichelli A, Dufour C, Saa-Wp E (2013) Diagnosis of acquired aplastic anaemia. Bone Marrow Transplant 48:162–167

Article  PubMed  CAS  Google Scholar 

Locasciulli A, Oneto R, Bacigalupo A et al (2007) Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade: a report from the European Group for Blood and Marrow Transplantation. Haematologica 92:11–18

Article  PubMed  CAS  Google Scholar 

Hochsmann B, Moicean A, Risitano A, Ljungman P, Schrezenmeier H (2013) Supportive care in severe and very severe aplastic anemia. Bone Marrow Transplant 48:168–173

Article  PubMed  CAS  Google Scholar 

Foukaneli T, Kerr P, Bolton-Maggs PH, Cardigan R, Coles A, Gennery A, Jane D, Kumararatne D, Manson A, New HV, Torpey N and (2020) Guidelines on the use of irradiated blood components. Br J Haematol 191:704–724

Article  PubMed  Google Scholar 

Malhotra P, John JM (2015) Supportive Care and Newer Therapies in Aplastic Anaemia. J Assoc Physicians India 63(3 Suppl):26–29

PubMed  Google Scholar 

Valdez JM, Scheinberg P, Nunez O, Wu OC, Young NS, Walsh TJ (2011) Decreased Infection-Related Mortality and Improved Survival in Severe Aplastic Anemia in the Past Two Decades. Clin Infect Dis 52:726–735

Article  PubMed  PubMed Central  Google Scholar 

Tomblyn M, Chiller T, Einsele H, Gress R, Sepkowitz K, Storek J et al (2009) Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Biol Blood Marrow Transplant 15:1143–1238

Article  PubMed  PubMed Central  CAS  Google Scholar 

Desmarets M, Cadwell CM, Peterson KR, Neades R, Zimring JC (2009) Minor histocompatibility antigens on transfused leukoreduced units of red blood cells induce bone marrow transplant rejection in a mouse model. Blood 114:2315–2322

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bhatia V, Raghuwanshi B, Sahoo J (2016) Current status of blood banks in India. Glob J Transfus Med 1:72–74

Article  Google Scholar 

Estcourt LJ, Desborough M, Brunskill SJ, Doree C, Hopewell S, Murphy MF et al (2016) Antifibrinolytic (lysine analogues) for the prevention of bleeding in people with haematological disorders.Cochrane Database Syst Rev:CD009733

Scheinberg P, Nunez O, Weinstein B et al (2011) Horse versus rabbit antithymocyte globulin in acquired aplastic anemia. N Engl J Med 365(5):430–438

Article  PubMed  PubMed Central  CAS  Google Scholar 

Teramura M, Kimura A, Iwase S, Yonemura Y, Nakao S, Urabe A et al (2007) Treatment of severe aplastic anemia with antithymocyteglobulin and cyclosporin A with or without G-CSF in adults: a multicenter randomized study in Japan. Blood 110:1756–1761

Article  PubMed  CAS  Google Scholar 

Bacigalupo A, Bruno B, Saracco P et al (2000) Antilymphocyteglobulin, cyclosporine, prednisolone, and granulocyte colony stimulating factor for severe aplastic anemia: an update of the GITMO/EBMT study on 100 patients: European Group for Blood and Marrow Transplantation (EBMT) Working Party on Severe Aplastic Anemia and the Gruppo Italiano Trapianti di Midolio Osseo (GITMO). Blood 95:1931–1934

Article  PubMed  CAS  Google Scholar 

Hayakawa J, Kanda J, Akahoshi Y et al (2017) Meta-analysis of treatment with rabbit and horse antithymocyte globulin for aplastic anemia. Int J Hematol 105:578

Article  PubMed  CAS  Google Scholar 

Scheinberg P, Wu CO, Nunez O, Scheinberg P, Boss C, Sloand EM et al (2009) Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study. Haematologica 94:348–354

Article  PubMed  PubMed Central  CAS  Google Scholar 

Rosenfeld SJ, Kimball J, Vining D, Young NS (1995) Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia. Blood 85:3058–3065

Article  PubMed  CAS  Google Scholar 

Rosenfeld S, Follmann D, Nunez O, Young NS (2003) Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome. JAMA 289:1130–1135

Article  PubMed  CAS  Google Scholar