Epidemiology, Diagnosis, Pathophysiology, and Initial Approach to Heart Failure with Preserved Ejection Fraction

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Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.

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Skeletal muscle mitochondrial content, oxidative capacity, and mfn2 expression are reduced in older patients with heart failure and preserved ejection fraction and are related to exercise intolerance.

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