The global health and economic burden of hospitalizations for heart failure.
J Am Coll Cardiol. 63: 1123-1133Owan T.E. Jacobsen S.J. Redfield M.M.Trends in prevalence and outcome of heart failure with preserved ejection fraction.
N Engl J Med. 9: 251-259Global public health burden of heart failure.
Card Fail Rev. 03: 7Vaduganathan M. Patel R.B. Michel A. et al.Mode of death in heart failure with preserved ejection fraction.
J Am Coll Cardiol. 69: 556-569Fonarow G.C. Abraham W.T. Albert N.M. et al.Association between performance measures and clinical outcomes for patients hospitalized with heart failure.
JAMA. 297: 61Steinberg B.A. Zhao X. Heidenreich P.A. et al.Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes.
Circulation. 126: 65-75Henkel D.M. Redfield M.M. Weston S.A. et al.Death in heart failure: a community perspective.
Circ Heart Fail. 1: 91-97Lin Y. Fu S. Yao Y. et al.Heart failure with preserved ejection fraction based on aging and comorbidities.
J Transl Med. 19: 291The pathophysiology of heart failure with preserved ejection fraction.
Nat Rev Cardiol. 11: 507-515Redfield M.M. Jacobsen S.J. Burnett J.C. et al.Burden of systolic and diastolic ventricular dysfunction in the community appreciating the scope of the heart failure epidemic.
ACC Curr J Rev. 12: 50-51Gevaert A.B. Boen J.R.A. Segers V.F. et al.Heart failure with preserved ejection fraction: a review of cardiac and noncardiac pathophysiology.
Front Physiol. 10: 638Redfield M.M. Jacobsen S.J. Borlaug B.A. et al.Age- and gender-related ventricular-vascular stiffening: a community-based study.
Circulation. 112: 2254-2262Shah A.M. Claggett B. Kitzman D. et al.Contemporary assessment of left ventricular diastolic function in older adults: the atherosclerosis risk in communities study.
Circulation. 135: 426-439Pandey A. Shah S.J. Butler J. et al.Exercise intolerance in older adults with heart failure with preserved ejection fraction.
J Am Coll Cardiol. 78: 1166-1187Tadic M. Cuspidi C. Plein S. et al.Sex and heart failure with preserved ejection fraction: from pathophysiology to clinical studies.
J Clin Med. 8: 792https://doi.org/10.3390/jcm8060792Dunlay S.M. Roger V.L. Weston S.A. et al.Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction.
Circ Heart Fail. 5: 720-726Masoudi F.A. Havranek E.P. Smith G. et al.Gender, age, and heart failure with preserved left ventricular systolic function.
J Am Coll Cardiol. 41: 217-223Brouwers F.P. de Boer R.A. van der Harst P. et al.Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND.
Eur Heart J. 34: 1424-1431Ho J.E. Enserro D. Brouwers F.P. et al.Predicting heart failure with preserved and reduced ejection fraction: the international collaboration on heart failure subtypes.
Circ Heart Fail. 9https://doi.org/10.1161/CIRCHEARTFAILURE.115.003116Sharma K. Mok Y. Kwak L. et al.Predictors of mortality by sex and race in heart failure with preserved ejection fraction: ARIC Community Surveillance Study.
JAHA. 9https://doi.org/10.1161/JAHA.119.014669Sotomi Y. Hikoso S. Nakatani D. et al.Sex differences in heart failure with preserved ejection fraction.
JAHA. 10https://doi.org/10.1161/JAHA.120.018574Heidenreich P.A. Bozkurt B. Aguilar D. et al.2022 AHA/ACC/HFSA guideline for the management of heart failure.
J Am Coll Cardiol. 79: e263-e421Persson H. Lonn E. Edner M. et al.Diastolic dysfunction in heart failure with preserved systolic function: need for objective evidence.
J Am Coll Cardiol. 49: 687-694Shah A.M. Shah S.J. Anand I.S. et al.Cardiac structure and function in heart failure with preserved ejection fraction: baseline findings from the echocardiographic study of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial.
Circ Heart Fail. 7: 104-115Melenovsky V. Borlaug B.A. Rosen B. et al.Cardiovascular features of heart failure with preserved ejection fraction versus nonfailing hypertensive left ventricular hypertrophy in the urban baltimore community.
J Am Coll Cardiol. 49: 198-207Zile M.R. Gottdiener J.S. Hetzel S.J. et al.Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction.
Circulation. 124: 2491-2501Nayor M. Cooper L.L. Enserro D.M. et al.Left ventricular diastolic dysfunction in the community: impact of diagnostic criteria on the burden, correlates, and prognosis.
JAHA. 7Pritchett A.M. Mahoney D.W. Jacobsen S.J. et al.Diastolic dysfunction and left atrial volume.
J Am Coll Cardiol. 45: 87-92Shin S. Claggett B. Inciardi R.M. et al.Prognostic value of minimal left atrial volume in heart failure with preserved ejection fraction.
JAHA. 10e019545Fonarow G.C. Peacock W.F. Phillips C.O. et al.Admission B-type natriuretic peptide levels and in-hospital mortality in acute decompensated heart Failure.
J Am Coll Cardiol. 49: 1943-1950Verbrugge F.H. Omote K. Reddy Y.N.V. et al.Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality.
Eur Heart J. ()https://doi.org/10.1093/eurheartj/ehab911Anjan V.Y. Loftus T.M. Burke M.A. et al.Prevalence, clinical phenotype, and outcomes associated with normal b-type natriuretic peptide levels in heart failure with preserved ejection fraction.
The Am J Cardiol. 110: 870-876BNP: biomarker not perfect in heart failure with preserved ejection fraction.
Eur Heart J. 43: 1952-1954Zile M.R. Baicu C.F. Gaasch W.H.Diastolic heart failure — abnormalities in active relaxation and passive stiffness of the left ventricle.
N Engl J Med. 350: 1953-1959https://doi.org/10.1056/NEJMoa032566Simmonds S.J. Cuijpers I. Heymans S. et al.Cellular and molecular differences between HFpEF and HFrEF: a step ahead in an improved pathological understanding.
Cells. 9: 242Borlaug B.A. Kane G.C. Melenovsky V. et al.Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction.
Eur Heart J. 37: 3293-3302Wachter R. Schmidt-Schweda S. Westermann D. et al.Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure.
Eur Heart J. 30: 3027-3036Borlaug B.A. Jaber W.A. Ommen S.R. et al.Diastolic relaxation and compliance reserve during dynamic exercise in heart failure with preserved ejection fraction.
Heart. 97: 964-969Westermann D. Lindner D. Kasner M. et al.Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.
Circ Heart Fail. 4: 44-52Baicu C.F. Stroud J.D. Livesay V.A. et al.Changes in extracellular collagen matrix alter myocardial systolic performance.
Am J Physiology-Heart Circulatory Physiol. 284: H122-H132Yu C.M. Zhang Q. Yip G.W.K. et al.Diastolic and systolic asynchrony in patients with diastolic heart failure.
J Am Coll Cardiol. 49: 97-105Obokata M. Reddy Y.N.V. Borlaug B.A.Diastolic dysfunction and heart failure with preserved ejection fraction.
JACC: Cardiovasc Imaging. 13: 245-257Ohara T. Niebel C.L. Stewart K.C. et al.Loss of adrenergic augmentation of diastolic intra-lv pressure difference in patients with diastolic dysfunction.
JACC: Cardiovasc Imaging. 5: 861-870Obokata M. Olson T.P. Reddy Y.N.V. et al.Haemodynamics, dyspnoea, and pulmonary reserve in heart failure with preserved ejection fraction.
Eur Heart J. 39: 2810-2821Reddy Y.N.V. Olson T.P. Obokata M. et al.Hemodynamic Correlates and diagnostic role of cardiopulmonary exercise testing in heart failure with preserved ejection fraction.
JACC: Heart Fail. 6: 665-675Adamson P.B. Abraham W.T. Bourge R.C. et al.Wireless pulmonary artery pressure monitoring guides management to reduce decompensation in heart failure with preserved ejection fraction.
Circ Heart Fail. 7: 935-944Dorfs S. Zeh W. Hochholzer W. et al.Pulmonary capillary wedge pressure during exercise and long-term mortality in patients with suspected heart failure with preserved ejection fraction.
Eur Heart J. 35: 3103-3112Abraham W.T. Adamson P.B. Bourge R.C. et al.Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial.
The Lancet. 377: 658-666Borlaug B.A. Olson T.P. Lam C.S.P. et al.Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction.
J Am Coll Cardiol. 56: 845-854Borlaug B.A. Melenovsky V. Russell S.D. et al.Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction.
Circulation. 114: 2138-2147Abudiab M.M. Redfield M.M. Melenovsky V. et al.Cardiac output response to exercise in relation to metabolic demand in heart failure with preserved ejection fraction.
Eur J Heart Fail. 15: 776-785Reddy Y.N.V. Andersen M.J. Obokata M. et al.Arterial stiffening with exercise in patients with heart failure and preserved ejection fraction.
J Am Coll Cardiol. 70: 136-148Ennezat P.V. Lefetz Y. Maréchaux S. et al.Left ventricular abnormal response during dynamic exercise in patients with heart failure and preserved left ventricular ejection fraction at rest.
J Card Fail. 14: 475-480Aging and arterial stiffness.
Circ J. 74: 2257-2262Safar M.E. Czernichow S. Blacher J.Obesity, arterial stiffness, and cardiovascular risk.
JASN. 17: S109-S111Mohammed S.F. Borlaug B.A. Roger V.L. et al.Comorbidity and ventricular and vascular structure and function in heart failure with preserved ejection fraction: a community-based study.
Circ Heart Fail. 5: 710-719Fernandes-Silva M.M. Shah A.M. Claggett B. et al.Adiposity, body composition and ventricular-arterial stiffness in the elderly: the Atherosclerosis Risk in Communities Study: adiposity and ventricular-arterial stiffness.
Eur J Heart Fail. 20: 1191-1201Haykowsky M.J. Brubaker P.H. John J.M. et al.Determinants of exercise intolerance in elderly heart failure patients with preserved ejection fraction.
J Am Coll Cardiol. 58: 265-274Kitzman D.W. Herrington D.M. Brubaker P.H. et al.Carotid arterial stiffness and its relationship to exercise intolerance in older patients with heart failure and preserved ejection fraction.
Hypertension. 61: 112-119Kraigher-Krainer E. Shah A.M. Gupta D.K. et al.Impaired systolic function by strain imaging in heart failure with preserved ejection fraction.
J Am Coll Cardiol. 63: 447-456Park J.J. Park J.B. Park J.H. et al.Global longitudinal strain to predict mortality in patients with acute heart failure.
J Am Coll Cardiol. 71: 1947-1957Shah A.M. Claggett B. Sweitzer N.K. et al.Prognostic importance of impaired systolic function in heart failure with preserved ejection fraction and the impact of spironolactone.
Circulation. 132: 402-414Borlaug B.A. Lam C.S.P. Roger V.L. et al.Contractility and ventricular systolic stiffening in hypertensive heart disease.
J Am Coll Cardiol. 54: 410-418Tan Y.T. Wenzelburger F. Lee E. et al.The pathophysiology of heart failure with normal ejection fraction.
J Am Coll Cardiol. 54: 36-46Hasselberg N.E. Haugaa K.H. Sarvari S.I. et al.Left ventricular global longitudinal strain is associated with exercise capacity in failing hearts with preserved and reduced ejection fraction.
Eur Heart J - Cardiovasc Imaging. 16: 217-224Shah S.J. Lam C.S.P. Svedlund S. et al.Prevalence and correlates of coronary microvascular dysfunction in heart failure with preserved ejection fraction: PROMIS-HFpEF.
Eur Heart J. 39: 3439-3450Obokata M. Reddy Y.N.V. Melenovsky V. et al.Myocardial injury and cardiac reserve in patients with heart failure and preserved ejection fraction.
J Am Coll Cardiol. 72: 29-40Shah S.J. Kitzman D.W. Borlaug B.A. et al.Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap.
Circulation. 134: 73-90Comparison of endothelial vasodilator function, inflammatory markers, and N-terminal pro-brain natriuretic peptide in patients with or without chronotropic incompetence to exercise test.
Heart. 92: 609-614Phan T.T. Shivu G.N. Abozguia K. et al.Impaired heart rate recovery and chronotropic incompetence in patients with heart failure with preserved ejection fraction.
Circ Heart Fail. 3: 29-34Cole C.R. Blackstone E.H. Pashkow F.J. Snader C.E. Lauer M.S.Heart-rate recovery immediately after exercise as a predictor of mortality.
Heart. 341: 1351-1357Haykowsky M.J. Brubaker P.H. Morgan T.M. et al.Impaired aerobic capacity and physical functional performance in older heart failure patients with preserved ejection fraction: role of lean body mass.
The Journals Gerontol Ser A: Biol Sci Med Sci. 68: 968-975Dhakal B.P. Malhotra R. Murphy R.M. et al.Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: the role of abnormal peripheral oxygen extraction.
Circ Heart Fail. 8 (): 286-294https://doi.org/10.1161/CIRCHEARTFAILURE.114.001825Lee J.F. Barrett-O’Keefe Z. Nelson A.D. et al.Impaired skeletal muscle vasodilation during exercise in heart failure with preserved ejection fraction.
Int J Cardiol. 211: 14-21Tucker W.J. Haykowsky M.J. Seo Y. et al.Impaired exercise tolerance in heart failure: role of skeletal muscle morphology and function.
Curr Heart Fail Rep. 15: 323-331Metabolic and structural impairment of skeletal muscle in heart failure.
Heart Fail Rev. 18: 623-630Kitzman D.W. Nicklas B. Kraus W.E. et al.Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction.
Am J Physiology-Heart Circulatory Physiol. 306: H1364-H1370Haykowsky M.J. Kouba E.J. Brubaker P.H. et al.Skeletal muscle composition and its relation to exercise intolerance in older patients with heart failure and preserved ejection fraction.
The Am J Cardiol. 113: 1211-1216Kumar A.A. Kelly D.P. Chirinos J.A.Mitochondrial dysfunction in heart failure with preserved ejection fraction.
Circulation. 139: 1435-1450Molina A.J.A. Bharadwaj M.S. Van Horn C. et al.Skeletal muscle mitochondrial content, oxidative capacity, and mfn2 expression are reduced in older patients with heart failure and preserved ejection fraction and are related to exercise intolerance.
JACC: Heart Fail. 4: 636-645Houstis N.E. Eisman A.S. Pappagianopoulos P.P. et al.Exercise intolerance in heart failure with preserved ejection fraction: diagnosing and ranking its causes using personalized O 2 pathway analysis.
Circulation. 137: 148-161Haykowsky M.J. Brubaker P.H. Stewart K.P. et al.Effect of endurance training on the determinants of peak exercise oxygen consumption in elderly patients with stable compensated heart failure and preserved ejection fraction.
J Am Coll Cardiol. 60: 120-128Hornsby W.E. Sareini M.A. Golbus J.R. et al.Lower extremity function is independently associated with hospitalization burden in heart failure with preserved ejection fraction.
J Card Fail. 25: 2-9Sanders N.A. Supiano M.A. Lewis E.F. et al.The frailty syndrome and outcomes in the TOPCAT trial: frailty in HFpEF.
Eur J Heart Fail. 20: 1570-1577Cellular and molecular pathobiology of heart failure with preserved ejection fraction.
Nat Rev Cardiol. 18: 400-423A novel paradigm for heart failure with preserved ejection fraction.
J Am Coll Cardiol. 62: 263-271Franssen C. Chen S. Unger A. et al.Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction.
JACC: Heart Fail. 4: 312-324Cheng J.M. Akkerhuis K.M. Battes L.C. et al.Biomarkers of heart failure with normal ejection fraction: a systematic review.
Eur J Heart Fail. 15: 1350-1362Sanders-van Wijk S. van Empel V. Davarzani N. et al.Circulating biomarkers of distinct pathophysiological pathways in heart failure with preserved vs. reduced left ventricular ejection fraction: biomarkers in heart failure with preserved vs. reduced EF.
Eur J Heart Fail. 17: 1006-1014D’Elia E. Vaduganathan M. Gori M. et al.Role of biomarkers in cardiac structure phenotyping in heart failure with preserved ejection fraction: critical appraisal and practical use: role of biomarkers in cardiac structure phenotyping in HFpEF.
Eur J Heart Fail. 17: 1231-1239Kalogeropoulos A. Georgiopoulou V. Psaty B.M. et al.Inflammatory markers and incident heart failure risk in older adults.
J Am Coll Cardiol. 55: 2129-2137van Heerebeek L. Hamdani N. Falcão-Pires I. et al.Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.
Circulation. 126: 830-839Gigantic business: titin properties and function through thick and thin.
Circ Res. 114: 1052-1068Zile M.R. Baicu C.F. Ikonomidis J S. et al.Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin.
Circulation. 131: 1247-1259Borbély A. van der Velden J. Papp Z. et al.Cardiomyocyte stiffness in diastolic heart failure.
Circulation. 111: 774-781van Heerebeek L. Franssen C.P.M. Hamdani N. et al.Molecular and cellular basis for diastolic dysfunction.
Curr Heart Fail Rep. 9: 293-302Krüger M. Kötter S. Grützner A. et al.Protein Kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs.
Circ Res. 104: 87-94Kasner M. Westermann D. Lopez B. et al.Diastolic tissue Doppler indexes correlate with the degree of collagen expression and cross-linking in heart failure and normal ejection fraction.
J Am Coll Cardiol. 57: 977-985Cowley A.W. Abe M. Mori T. et al.Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension.
Am J Physiology-Renal Physiol. 308: F179-F197Solomon S.D. McMurray J.J.V. Anand I.S. et al.Angiotensin–Neprilysin inhibition in heart failure with preserved ejection fraction.
N Engl J Med. 381: 1609-1620Spironolactone use and improved outcomes in patients with heart failure with preserved ejection fraction with resistant hypertension.
JAHA. 9Tam M.C. Lee R. Cascino T.M. et al.Current perspectives on systemic hypertension in heart failure with preserved ejection fraction.
Curr Hypertens Rep. 19: 12Selvaraj S. Claggett B.L. Böhm M. et al.Systolic blood pressure in heart failure with preserved ejection fraction treated with sacubitril/valsartan.
J Am Coll Cardiol. 75: 1644-1656Yancy C.W. Jessup M. Bozkurt B. et al.2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical practice Guidelines and the Heart Failure Society of America.
Circulation. 136https://doi.org/10.1161/CIR.0000000000000509Savji N. Meijers W.C. Bartz T.M. et al.The association of obesity and cardiometabolic Traits with incident HFpEF and HFrEF.
JACC: Heart Fail. 6: 701-709Evaluation and management of heart failure with preserved ejection fraction.
Nat Rev Cardiol. 17: 559-573Pandey A. LaMonte M. Klein L. et al.Relationship between physical activity, body mass index, and risk of heart failure.
J Am Coll Cardiol. 69: 1129-1142Bhella P.S. Hastings J.L. Fujimoto N. et al.Impact of lifelong exercise “dose” on left ventricular compliance and distensibility.
J Am Coll Cardiol. 64: 1257-1266Pandey A. Cornwell W.K. Willis B. et al.Body mass index and cardiorespiratory fitness in mid-life and risk of heart failure hospitalization in older age.
JACC: Heart Fail. 5: 367-374Abdominal obesity is associated with an increased risk of all-cause mortality in patients with HFpEF.
J Am Coll Cardiol. 70: 2739-2749Haass M. Kitzman D.W. Anand I.S. et al.Body mass index and adverse cardiovascular outcomes in heart failure patients with preserved ejection fraction: results from the irbesartan in heart failure with preserved ejection fraction (I-PRESERVE) Trial.
Circ Heart Fail. 4: 324-331Beale A.L. Meyer P. Marwick T.H. et al.Sex differences in cardiovascular pathophysiology: why women are overrepresented in heart failure with preserved ejection fraction.
Circulation. 138: 198-205Sex differences in cardiovascular ageing.
Heart. 102: 825-831Tabit C.E. Chung W.B. Hamburg N.M. et al.Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications.
Rev Endocr Metab Disord. 11: 61-74Cheng S. Xanthakis V. Sullivan L.M. et al.Correlates of echocardiographic indices of cardiac remodeling over the adult life course: longitudinal observations from the framingham heart study.
Circulation. 122: 570-578van Heerebeek L. Hamdani N. Handoko M.L. et al.Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension.
Circulation. 117: 43-51McHugh K. DeVore A.D. Wu J. et al.Heart failure with preserved ejection fraction and diabetes.
J Am Coll Cardiol. 73: 602-611Dei Cas A. Khan S.S. Butler J. et al.Impact of diabetes on epidemiology, treatment, and outcomes of patients with heart failure.
JACC: Heart Fail. 3: 136-145Left atrial myopathy in heart failure with preserved ejection fraction.
Circ J. ()https://doi.org/10.1253/circj.CJ-21-0795Zakeri R. Chamberlain A.M. Roger V.L. et al.Temporal relationship and prognostic significance of atrial fibrillation in heart failure patients with preserved ejection fraction: a community-based study.
Circulation. 128: 1085-1093Santos A.B.S. Kraigher-Krainer E. Gupta D.K. et al.Impaired left atrial function in heart failure with preserved ejection fraction: impaired left atrial function in HFpEF.
Eur J Heart Fail. 16: 1096-1103Santos A.B.S. Roca G.Q.
留言 (0)