Turner, D. et al. STRIDE-II: an update on the selecting therapeutic targets in inflammatory bowel disease (STRIDE) initiative of the International Organization for the Study of IBD (IOIBD): determining therapeutic goals for treat-to-target strategies in IBD. Gastroenterology 160, 1570–1583 (2021).

CAS  Article  Google Scholar 

Kugathasan, S. et al. Prediction of complicated disease course for children newly diagnosed with Crohn’s disease: a multicentre inception cohort study. Lancet 389, 1710–1718 (2017).

Article  Google Scholar 

Dhaliwal, J. et al. Phenotypic variation in paediatric inflammatory bowel disease by age: a multicentre prospective inception cohort study of the Canadian Children IBD Network. J. Crohns Colitis 14, 445–454 (2020).

CAS  Article  Google Scholar 

Rinawi, F. et al. Long-term outcomes with adalimumab therapy in pediatric Crohn disease: associations with adalimumab exposure. J. Pediatr. Gastroenterol. Nutr. 74, 389–395 (2022).

CAS  Article  Google Scholar 

Assa, A. et al. Proactive monitoring of adalimumab trough concentration associated with increased clinical remission in children with Crohn’s disease compared with reactive monitoring. Gastroenterology 157, 985–996.e2 (2019).

CAS  Article  Google Scholar 

Mack, D. R. et al. Canadian Association of Gastroenterology Clinical Practice Guideline for the medical management of pediatric luminal Crohn’s disease. Gastroenterology 157, 320–348 (2019).

Article  Google Scholar 

Dubinsky, M. C. et al. Dashboard-driven accelerated infliximab induction dosing increases infliximab durability and reduces immunogenicity. Inflamm. Bowel Dis. 28, 1375–1385 (2022).

Article  Google Scholar 

Ungaro, R. C. et al. Systematic review and meta-analysis: efficacy and safety of early biologic treatment in adult and paediatric patients with Crohn’s disease. Aliment. Pharmacol. Ther. 51, 831–842 (2020).

Article  Google Scholar 

Hyams, J. S. et al. Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. Lancet 393, 1708–1720 (2019).

Article  Google Scholar 

Church, P. C. et al. Intensified infliximab induction is associated with improved response and decreased colectomy in steroid-refractory paediatric ulcerative colitis. J. Crohns Colitis 13, 982–989 (2019).

Article  Google Scholar