In high-risk patients who have undergone percutaneous coronary intervention (PCI), a follow-up strategy of routine functional testing does not improve outcomes at 2 years compared with standard care alone, according to findings from the POST-PCI trial presented at ESC.22. A total of 1,706 patients with high-risk anatomical or clinical characteristics who had undergone PCI were randomly assigned to a follow-up strategy of routine non-invasive stress testing at 1 year after PCI or to standard care alone. At 2 years, the incidence of the primary composite outcome of death, myocardial infarction, or hospitalization for unstable angina did not significantly differ between the two strategies (HR 0.90, 95% CI 0.61–1.35, P = 0.62). The incidences of invasive coronary angiography (12.3% versus 9.3%) and repeat revascularization after 1 year (8.1% versus 5.8%) were higher in the functional testing group.