Transthyretin Cardiac Amyloidosis

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Clinical characteristics of wild-type transthyretin cardiac amyloidosis: disproving myths.

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Nonbiopsy diagnosis of cardiac transthyretin amyloidosis.

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History of amyloidosis.

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Clinical importance of left atrial infiltration in cardiac transthyretin amyloidosis.

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Heart failure resulting from age-related cardiac amyloid disease associated with wild-type transthyretin: a prospective, observational cohort study.

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Hereditary transthyretin amyloidosis: a model of medical progress for a fatal disease.

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Genotype and phenotype of transthyretin cardiac amyloidosis: THAOS (transthyretin amyloid outcome Survey).

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Hereditary transthyretin amyloidosis from a Scandinavian perspective.

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Ocular manifestations of familial transthyretin amyloidosis.

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Natural history of wild-type transthyretin cardiac amyloidosis and risk stratification using a novel staging system.

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A new staging system for cardiac transthyretin amyloidosis.

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Diuretic dose and NYHA functional class are independent predictors of mortality in patients with transthyretin cardiac amyloidosis.

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Tenosynovial and cardiac amyloidosis inpatients undergoing carpal tunnel release.

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Association between ruptured distal biceps tendon and wild-type transthyretin cardiac amyloidosis.

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Transthyretin-derived amyloidosis: probably a common cause of lumbar spinal stenosis.

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Unveiling transthyretin cardiac amyloidosis and its predictors among elderly patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.

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Prevalence of cardiac amyloidosis in patients referred for transcatheter aortic valve replacement.

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Aortic stenosis and cardiac amyloidosis: JACC review topic of the week.

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Aortic stenosis and transthyretin cardiac amyloidosis: the chicken or the egg?.

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Coexistence of degenerative aortic stenosis and wild-type transthyretin-related cardiac amyloidosis.

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Occult transthyretin cardiac amyloid in severe Calcific aortic stenosis: prevalence and prognosis in patients undergoing Surgical aortic valve replacement.

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Amyloidosis cardiomyopathy: update in the diagnosis and treatment of the most common types.

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Diagnosis of cardiac amyloidosis: a systematic review on the role of imaging and biomarkers.

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Prevalence and prognostic significance of low QRS voltage among the three main types of cardiac amyloidosis.

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Amyloid cardiomyopathy.

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Echocardiographic findings in cardiac amyloidosis: inside two-dimensional, Doppler, and strain imaging.

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Addressing common questions encountered in the diagnosis and management of cardiac amyloidosis.

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The role of cardiac MR imaging in the assessment of patients with cardiac amyloidosis.

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Native T1 mapping in transthyretin amyloidosis.

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(99m)Tc-pyrophosphate scintigraphy for differentiating light-chain cardiac amyloidosis from the transthyretin-related familial and senile cardiac amyloidoses.

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Bone scintigraphy with99mtechnetium-hydroxymethylene diphosphonate allows early diagnosis of cardiac involvement in patients with transthyretin-derived systemic amyloidosis.

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Diagnostic sensitivity of abdominal fat aspiration in cardiac amyloidosis.

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Fine-needle aspiration of abdominal fat pad for amyloid detection: a clinically useful test?.

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Yield of noncardiac biopsy for the diagnosis of transthyretin cardiac amyloidosis.

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Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.

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Expert consensus recommendations for the suspicion and diagnosis of transthyretin cardiac amyloidosis.

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Left ventricular systolic dysfunction precipitated by verapamil in cardiac amyloidosis.

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Selective binding of nifedipine to amyloid fibrils.

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Digoxin use in cardiac amyloidosis.

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Current concepts of cardiac amyloidosis: diagnosis, clinical management, and the need for collaboration.

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Spironolactone in patients with an echocardiographic HFpEF phenotype suggestive of cardiac amyloidosis: results from TOPCAT.

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Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience: atrial fibrillation in wild-type transthyretin amyloidosis.

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Direct current cardioversion of atrial arrhythmias in adults with cardiac amyloidosis.

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Intracardiac thrombosis and embolism in patients with cardiac amyloidosis.

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Electrophysiologic assessment of conduction abnormalities and atrial arrhythmias associated with amyloid cardiomyopathy.

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Atrial fibrillation ablation in patients with transthyretin cardiac amyloidosis.

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A peak into the pace of cardiac amyloidosis.

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Cardiac devices in patients with transthyretin amyloidosis: impact on functional class, left ventricular function, mitral regurgitation, and mortality.

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Hsu management of arrhythmias in cardiac amyloidosis.

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Implantable cardioverter defibrillators in patients with cardiac amyloidosis: ICD in cardiac amyloidosis.

J Cardiovasc Electrophysiol. 24: 793-798

Rehorn MR, Loungani RS, Black-Maier E, et al. Cardiac Implantable Electronic Devices: A Window Into the Evolution of Conduction Disease in Cardiac Amyloidosis. JACC Clin Electrophysiol 2020:6(9):1144-1154. doi:10.1016/j.jacep.2020.04.020. Epub 2020 Aug 26. PMID: 32972550.

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Transthyretin stabilization by AG10 in symptomatic transthyretin amyloid cardiomyopathy.

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The use of diflunisal for transthyretin cardiac amyloidosis: a review.

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Inotersen treatment for patients with hereditary transthyretin amyloidosis.

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Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study.

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CRISPR-Cas9 in vivo gene editing for transthyretin amyloidosis.

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Pathophysiology and therapeutic approaches to cardiac amyloidosis.

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Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.

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Patisiran, an RNAi therapeutic, for hereditary transthyretin amyloidosis.

N Engl J Med. 379: 11-21Maurer M.S. Schwartz J.H. Gundapaneni B. et al.

Tafamidis treatment for patients with transthyretin amyloid cardiomyopathy.

N Engl J Med. 379: 1007-1016Elliott P. Drachman B.M. Gottlieb S.S. et al.

Long-term survival with tafamidis in patients with transthyretin amyloid cardiomyopathy.

Circ Heart Fail. 15: e008193

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