Dementia and Geriatric Cognitive Disorders
Honjo Y.a,b,c,d,e· Kawasaki I.e· Nagai K.e· Harada S.e· Ogawa N.eaMemory Clinic, Kyoto Kaisei Hospital, Kyoto, Japan
bMemory Clinic, Kyoto Miniren Asukai Hospital, Kyoto, Japan
cMemory Clinic, Seika-town National Health Insurance Hospital, Kyoto, Japan
dMemory Clinic, Kyoto Narabigaoka Hospital, Kyoto, Japan
eDepartment of Occupational Therapy, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto, Japan
Dement Geriatr Cogn Disord
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Article / Publication DetailsFirst-Page Preview
Received: April 11, 2022
Accepted: June 14, 2022
Published online: July 12, 2022
Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 4
ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)
For additional information: https://www.karger.com/DEM
AbstractIntroduction: Alzheimer’s disease (AD) is the most common cognitive disease, and behavioral and psychological symptoms of dementia (BPSD) can place a heavy burden on families. The presence of these symptoms related to AD is commonly assessed using the Neuropsychiatric Inventory Questionnaire (NPI-Q). This study sought to clarify the relationship between scores on the 12-domain NPI-Q and individual factors in patients with AD. Methods: Participants were 218 new outpatients with AD at five memory clinics. Cognitive function was assessed using the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental State Examination (MMSE). We examined which individual factors were associated with the total NPI-Q score and the number of domains. We also examined which domains were associated with the factors identified. Results: A higher total NPI score was significantly associated with lower scores on both cognitive assessments and a longer duration of education. Exhibiting symptoms on a greater number of domains was significantly associated with lower scores on both cognitive assessments, longer duration of education, and advanced age. The nighttime disturbances domain was significantly associated with lower scores on both cognitive assessments and advanced age. The delusions domain was significantly associated with lower education. Conclusions: BPSD may appear more easily with reduced quality of life and ongoing dissatisfaction. Effective individualized services are important for patients with AD, and therefore, we should account for age, cognitive function, and duration of education in the services provided.
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References Nakanishi M, Nakashima T. Features of the Japanese national dementia strategy in comparison with international dementia policies: how should a national dementia policy interact with the public health- and social-care systems? Alzheimers Dement. 2014 Jul;10(4):468–76.e3. Crous-Bou M, Minguillón C, Gramunt N, Molinuevo JL. Alzheimer’s disease prevention: from risk factors to early intervention. Alzheimers Res Ther. 2017 Sep 12;9(1):71. Van der Mussele S, Mariën P, Saerens J, Somers N, Goeman J, De Deyn PP, et al. Psychosis associated behavioral and psychological signs and symptoms in mild cognitive impairment and Alzheimer’s dementia. Aging Ment Health. 2015;19(9):818–28. Kaufer DI, Cummings JL, Ketchel P, Smith V, MacMillan A, Shelley T, et al. Validation of the NPI-Q: a brief clinical form of the neuropsychiatric inventory. J Neuropsychiatry Clin Neurosci. 2000;12(2):233–9. Lin PC, Lin HT, Yang YH, Yang YH. The effects of caregiver characteristics on behavioral and psychological symptoms of dementia of patients with dementia. Aging Ment Health. 2022 Feb;26(2):263–9. Katoh S, Shimogaki H, Onodera A, Ueda H, Oikawa K, Ikeda K, et al. Development of the revised version of Hasegawa’s Dementia Scale (HDS-R) (in Japanese). RounenSeishin Igaku Zasshi. 1991;2:1339–47. Hosokawa T, Yamada Y, Isagoda A, Nakamura R. Psychometric equivalence of the Hasegawa dementia scale-revised with the mini-mental state examination in stroke patients. Percept Mot Skills. 1994 Aug;79(1):664–6. Jeong JW, Kim KW, Lee DY, Lee SB, Park JH, Choi EA, et al. A normative study of the revised Hasegawa dementia Scale: comparison of demographic influences between the revised Hasegawa dementia Scale and the mini-mental status examination. Dement Geriatr Cogn Disord. 2007;24(4):288–93. Kounnavong S, Soundavong K, Xayavong S, Vongpraserth N, Bounsavath P, Houatthongkham S, et al. Lao language version of the revised Hasegawa’s Dementia Scale. Nagoya J Med Sci. 2017 Feb;79(2):241–9. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. J Psychiatr Res. 1975 Nov;12(3):189–98. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, fifth edition DMS-5. Arlington, VA: American Psychiatric Association; 2013. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, et al. The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement. 2011 May;7(3):263–9. Leung DKY, Chan WC, Spector A, Wong GHY. Prevalence of depression, anxiety, and apathy symptoms across dementia stages: a systematic review and meta-analysis. Int J Geriatr Psychiatry. 2021 Sep;36(9):1330–44. Maki Y, Amari M, Yamaguchi T, Nakaaki S, Yamaguchi H. Anosognosia: patients’ distress and self-awareness of deficits in Alzheimer’s disease. Am J Alzheimers Dis Other Demen. 2012 Aug;27(5):339–45. Article / Publication DetailsFirst-Page Preview
Received: April 11, 2022
Accepted: June 14, 2022
Published online: July 12, 2022
Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 4
ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)
For additional information: https://www.karger.com/DEM
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