Dementia and Geriatric Cognitive Disorders

Sloane K.L.a· Fabian R.b· Wright A.b· Saxena S.b· Kim K.b· Stein C.M.b· Keser Z.b· Glenn S.c· Hillis A.E.b

Author affiliations

aDepartment of Neurology, University of Pennsylvania and The Crescenz Veterans Affairs Medical Center, Philadelphia, Philadelphia, PA, USA
bDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
cMiro, a Division of Cognitive Healthcare Company, San Francisco, CA, USA

Dement Geriatr Cogn Disord

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Article / Publication Details

First-Page Preview

Received: March 03, 2022
Accepted: September 05, 2022
Published online: March 30, 2023

Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 7

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: https://www.karger.com/DEM

Abstract

Introduction: As the population ages, the prevalence of cognitive impairment is expanding. Given the recent pandemic, there is a need for remote testing modalities to assess cognitive deficits in individuals with neurological disorders. Self-administered, remote, tablet-based cognitive assessments would be clinically valuable if they can detect and classify cognitive deficits as effectively as traditional in-person neuropsychological testing. Methods: We tested whether the Miro application, a tablet-based neurocognitive platform, measured the same cognitive domains as traditional pencil-and-paper neuropsychological tests. Seventy-nine patients were recruited and then randomized to either undergo pencil-and-paper or tablet testing first. Twenty-nine age-matched healthy controls completed the tablet-based assessments. We identified Pearson correlations between Miro tablet-based modules and corresponding neuropsychological tests in patients and compared scores of patients with neurological disorders with those of healthy controls using t tests. Results: Statistically significant Pearson correlations between the neuropsychological tests and their tablet equivalents were found for all domains with moderate (r > 0.3) or strong (r > 0.7) correlations in 16 of 17 tests (p < 0.05). All tablet-based subtests differentiated healthy controls from neurologically impaired patients by t tests except for the spatial span forward and finger tapping modules. Participants reported enjoyment of the tablet-based testing, denied that it provoked anxiety, and noted no preference between modalities. Conclusions: This tablet-based application was found to be widely acceptable to participants. This study supports the validity of these tablet-based assessments in the differentiation of healthy controls from patients with neurocognitive deficits in a variety of cognitive domains and across multiple neurological disease etiologies.

© 2023 S. Karger AG, Basel

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First-Page Preview

Received: March 03, 2022
Accepted: September 05, 2022
Published online: March 30, 2023

Number of Print Pages: 9
Number of Figures: 1
Number of Tables: 7

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: https://www.karger.com/DEM

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