Wright MO, Crawford E, Del Castillo D. Childhood emotional maltreatment and later psychological distress among college students: the mediating role of maladaptive schemas. Child Abus Negl. 2009;33:59–68.

Article  Google Scholar 

Messina N, Marinelli-Casey P, Hillhouse M, Rawson R, Hunter J, Ang A. Childhood adverse events and methamphetamine use among men and women. J Psychoact Drugs. 2008;40(sup5):399–409.

Article  Google Scholar 

Lopez-Patton M, Kumar M, Jones D, Fonseca M, Kumar AM, Nemeroff CB. Childhood trauma and METH abuse among men who have sex with men: Implications for intervention. J Psychiatr Res. 2016;72:1–5.

PubMed  Article  Google Scholar 

Huang C, Yuan Q, Zhang L, Wang L, Cui S, Zhang K, et al. Associations between childhood trauma and the age of first-time drug use in methamphetamine-dependent patients. Front. Psychiatry. 2021;12:658205. https://doi.org/10.3389/fpsyt.2021.658205.

U.S. Department of Health and Human Services Children’s Bureau. Child Maltreatment 2019. Washington NDACAN; 2019.

Lukas M, Bredewold R, Neumann ID, Veenema AH. Maternal separation interferes with developmental changes in brain vasopressin and oxytocin receptor binding in male rats. Neuropharmacology 2010;58:78–87.

CAS  PubMed  Article  Google Scholar 

Oreland S, Gustafsson-Ericson L, Nylander I. Short- and long-term consequences of different early environmental conditions on central immunoreactive oxytocin and arginine vasopressin levels in male rats. Neuropeptides 2010;44:391–8.

CAS  PubMed  Article  Google Scholar 

Baracz SJ, Everett NA, Cornish JL. The impact of early life stress on the central oxytocin system and susceptibility for drug addiction: Applicability of oxytocin as a pharmacotherapy. Neurosci Biobehav. Rev. 2020;110:114–32.

CAS  PubMed  Article  Google Scholar 

Buisman-Pijlman FT, Sumracki NM, Gordon JJ, Hull PR, Carter CS, Tops M. Individual differences underlying susceptibility to addiction: Role for the endogenous oxytocin system. Pharm Biochem Behav. 2014;119:22–38.

CAS  Article  Google Scholar 

Amini-Khoei H, Mohammadi-Asl A, Amiri S, Hosseini M-J, Momeny M, Hassanipour M, et al. Oxytocin mitigated the depressive-like behaviors of maternal separation stress through modulating mitochondrial function and neuroinflammation. Prog Neuro-Psychopharmacol Biol Psychiatry. 2017;76:169–78.

CAS  Article  Google Scholar 

Ji H, Su W, Zhou R, Feng J, Lin Y, Zhang Y, et al. Intranasal oxytocin administration improves depression-like behaviors in adult rats that experienced neonatal maternal deprivation. Behav. Pharmacol. 2016;27:689–96.

CAS  PubMed  Article  Google Scholar 

Thornton JL, Everett NA, Webb P, Turner AJ, Cornish JL, Baracz SJ. Adolescent oxytocin administration reduces depression-like behaviour induced by early life stress in adult male and female rats. Prog Neuro-Psychopharmacol Biol Psychiatry. 2021;110:110279.

CAS  Article  Google Scholar 

Gunnar MR, DePasquale CE, Reid BM, Donzella B. Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children. Proc Natl Acad Sci USA. 2019;48:23984–8.

Article  CAS  Google Scholar 

Baracz SJ, Everett NA, Robinson KJ, Campbell GR, Cornish JL. Maternal separation changes maternal care, anxiety-like behaviour and expression of paraventricular oxytocin and corticotrophin-releasing factor immunoreactivity in lactating rats. J Neuroendocrinol. 2020;32:e12861.

CAS  PubMed  Article  Google Scholar 

Lundberg S, Abelson KSP, Nylander I, Roman E. Few long-term consequences after prolonged maternal separation in female Wistar rats. PLoS ONE. 2017;12:e0190042.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Bian Y, Yang L, Wang Z, Wang Q, Zeng L, Xu G. Repeated three-hour maternal separation induces depression-like behavior and affects the expression of hippocampal plasticity-related proteins in C57BL/6N mice. Neural Plast. 2015;2015:1–7.

Article  CAS  Google Scholar 

Hensleigh E, Pritchard LM. The effect of early environment manipulation on locomotor sensitivity and methamphetamine conditioned place preference reward. Behav. Brain Res. 2014;268:66–71.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Lewis CR, Bastle RM, Manning TB, Himes SM, Fennig P, Conrad PR, et al. Interactions between early life stress, nucleus accumbens MeCP2 expression, and methamphetamine self-administration in male rats. Neuropsychopharmacology 2016;41:2851–61.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Spear LP, Swartzwelder HS. Adolescent alcohol exposure and persistence of adolescent-typical phenotypes into adulthood: A mini-review. Neurosci Biobehav Rev. 2014;45:1–8.

PubMed  Article  Google Scholar 

Hicks C, Cornish JL, Baracz SJ, Suraev AS, McGregor IS. Adolescent pre-treatment with oxytocin protects against adult methamphetamine-seeking behavior in female rats. Addiction Biol. 2016;21:304–15.

CAS  Article  Google Scholar 

Everett NA, Baracz SJ, Cornish JL. The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety. Neuropsychopharmacology 2020;45:597–605.

PubMed  Article  Google Scholar 

Bowen MT, Carson DS, Spiro A, Arnold JC, McGregor IS. Adolescent oxytocin exposure causes persistent reductions in anxiety and alcohol consumption and enhances sociability in rats. PLOS ONE. 2011;6:e27237.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Potegal M, Einon D. Aggressive behaviors in adult rats deprived of playfighting experience as juveniles. Dev Psychobiol. 1989;22:159–72.

CAS  PubMed  Article  Google Scholar 

Baracz SJ, Everett NA, Cornish JL. The involvement of oxytocin in the subthalamic nucleus on relapse to methamphetamine-seeking behaviour. PLOS ONE. 2015;10. https://doi.org/10.1371/journal.pone.0136132.

Moran-Santa Maria MM, McRae-Clark A, Baker NL, Ramakrishnan V, Brady KT. Yohimbine administration and cue-reactivity in cocaine-dependent individuals. Psychopharmacology. 2014;231:4157–65.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Shepard JD, Bossert JM, Liu SY, Shaham Y. The anxiogenic drug yohimbine reinstates methamphetamine seeking in a rat model of drug relapse. Biol Psychiatry. 2004;55:1082–9.

CAS  PubMed  Article  Google Scholar 

O’Malley D, Dinan TG, Cryan JF. Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: differential effects of acute psychological and physical stressors. Peptides 2010;31:662–70.

PubMed  Article  CAS  Google Scholar 

O’Malley D, Dinan TG, Cryan JF. Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood. Psychopharmacology. 2011;214:221–9.

PubMed  Article  CAS  Google Scholar 

Plotsky PM, Meaney MJ. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Mol Brain Res. 1993;18:195–200.

CAS  PubMed  Article  Google Scholar 

Baracz SJ, Parker LM, Suraev AS, Everett NA, Goodchild AK, McGregor IS, et al. Chronic methamphetamine self-administration dysregulates oxytocin plasma levels and oxytocin receptor fibre density in the nucleus accumbens core and subthalamic nucleus of the rat. J Neuroendocrinol. 2016;28:1–13.

Article  CAS  Google Scholar 

Nawa N, Nakamura K, Fujiwara T. Oxytocin response following playful mother–child interaction in survivors of the Great East Japan Earthquake. Front. Psychiatry. 2020;11:477. https://doi.org/10.3389/fpsyt.2020.00477. eCollection 2020.

Das M, Vihlen CS, Legradi G. Hypothalamic and brainstem sources of pituitary adenylate cyclase-activating polypeptide nerve fibers innervating the hypothalamic paraventricular nucleus in the rat. J Comp Neurol. 2007;500:761–76.

PubMed  PubMed Central  Article  Google Scholar 

Dandi Ε, Kalamari A, Touloumi O, Lagoudaki R, Nousiopoulou E, Simeonidou C, et al. Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress. Int J Dev. Neurosci. 2018;67:19–32.

CAS  Article  Google Scholar 

Kambali MY, Anshu K, Kutty BM, Muddashetty RS, Laxmi TR. Effect of early maternal separation stress on attention, spatial learning and social interaction behaviour. Exp Brain Res. 2019;237:1993–2010.

PubMed  Article  Google Scholar 

Banqueri M, Méndez M, Arias JL. Behavioral effects in adolescence and early adulthood in two length models of maternal separation in male rats. Behav. Brain Res. 2017;324:77–86.

PubMed  Article  Google Scholar 

Veenema AH, Blume A, Niederle D, Buwalda B, Neumann ID. Effects of early life stress on adult male aggression and hypothalamic vasopressin and serotonin. Eur J Neurosci. 2006;24:1711–20.

PubMed  Article  Google Scholar 

de Jong TR, Neumann ID. Oxytocin and aggression. In: Hurlemann R, Grinevich V, editors. Behavioral pharmacology of neuropeptides: oxytocin. Cham: Springer International Publishing; 2018. 175-92.

Plotsky PM, Thrivikraman KV, Nemeroff CB, Caldji C, Sharma S, Meaney MJ. Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology 2005;30:2192–204.

CAS  PubMed  Article  Google Scholar 

Babygirija R, Yoshimoto S, Gribovskaja-Rupp I, Bülbül M, Ludwig K, Takahashi T. Social interaction attenuates stress responses following chronic stress in maternally separated rats. Brain Res. 2012;1469:54–62.

CAS  PubMed  Article  Google Scholar 

Aisa B, Tordera R, Lasheras B, Del Río J, Ramírez MJ. Effects of maternal separation on hypothalamic-pituitary-adrenal responses, cognition and vulnerability to stress in adult female rats. Neuroscience 2008;154:1218–26.

CAS  PubMed  Article  Google Scholar 

Marais L, van Rensburg SJ, van Zyl JM, Stein DJ, Daniels WMU. Maternal separation of rat pups increases the risk of developing depressive-like behavior after subsequent chronic stress by altering corticosterone and neurotrophin levels in the hippocampus. Neurosci Res. 2008;61:106–12.

CAS  PubMed  Article  Google Scholar 

Koe AS, Salzberg MR, Morris MJ, O’Brien TJ, Jones NC. Early life maternal separation stress augmentation of limbic epileptogenesis: The role of corticosterone and HPA axis programming. Psychoneuroendocrinology 2014;42:124–33.

CAS  PubMed  Article  Google Scholar