Patch Clamp: The First Four Decades of a Technique That Revolutionized Electrophysiology and Beyond

Almers W, Stanfield PR, Stühmer W (1983) Lateral distribution of sodium and potassium channels in frog skeletal muscle: measurements with a patch clamp method. J Physiol 336:261–284

Google Scholar 

Böck J, Krogsaeter E, Passon M, Chao YK, Sharma S, Grallert H, Peters A, Grimm C (2021) Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect. PLoS Genet 17(1):e1009236

Google Scholar 

Brenowitz S, Duguid I, Kammermeier PJ (2017) Ion channels: history, diversity, and impact. Cold Spring Harb Protoc 7. https://doi.org/10.1101/pdb.top092288

Caccavano A, Bozzelli PL, Forcelli PA, Pak DTS, Wu JY, Conant K, Vicini S (2020) Inhibitory parvalbumin basket cell activity is selectively reduced during hippocampal sharp wave ripples in a mouse model of familial Alzheimer’s disease. J Neurosci 40:5116–5136

Google Scholar 

Carabelli V, Giancippoli A, Baldelli P, Carbone E, Artalejo AR (2003) Distinct potentiation of L-type currents and secretion by cAMP in rat chromaffin cells. Biophys J 85:1326–1337

Google Scholar 

Clarke SG, Scarnati MS, Paradiso KG (2016) Neurotransmitter release can be stabilized by a mechanism that prevents voltage changes near the end of action potentials from affecting calcium currents. J Neurosci 36:11559–11572

Google Scholar 

Colquhoun D (1991) Ion channels: this year’s Nobel prize in physiology or medicine. Opening channels of communication. Br Med J 303:938–939

Google Scholar 

Colquhoun D, Hawkes AG (1981) On the stochastic properties of single ion channels. Proc R Soc Lond B Biol Sci 211:205–235

Google Scholar 

Conti F, Neher E (1980) Single channel recordings of K+ currents in squid axons. Nature 285:140–143

Google Scholar 

Conti F, DeFelice LJ, Wanke E (1975) Potassium and sodium ion current noise in the membrane of the squid giant axon. J Physiol 248:45–82

Google Scholar 

Conti F, Hille B, Neumcke B, Nonner W, Stämpfli R (1976) Measurement of the conductance of the sodium channel from current fluctuations at the node of Ranvier. J Physiol 262:699–727

Google Scholar 

Damann N, Voets T, Nilius B (2008) TRPs in our senses. Curr Biol 18:R880–R889

Google Scholar 

Edwards FA, Konnerth A, Sakmann B, Takahashi T (1989) A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflugers Arch 414:600–612

Google Scholar 

Espacenet (n.d.). https://worldwide.espacenet.com/advancedSearch?locale=en_ep

Ferraro M, Levi R, Lovisolo D, Vadacchino M (1983) Voltage noise in honeybee drone photoreceptors. Biophys Struct Mech 10:129–142

Google Scholar 

Gao M, Lim S, Chubykin AA (2021) Visual familiarity induced 5-Hz oscillations and improved orientation and direction selectivities in V1. J Neurosci 41:2656–2667

Google Scholar 

Gericke M, Droogmans G, Nilius B (1993) Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells. Pflugers Arch 422:552–557

Google Scholar 

Gray R, Johnston D (1985) Rectification of single GABA-gated chloride channels in adult hippocampal neurons. J Neurophysiol 54:134–142

Google Scholar 

Halliwell RF (2007) A short history of the rise of the molecular pharmacology of ionotropic drug receptors. Trends Pharmacol Sci 28:214–218

Google Scholar 

Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85–100

Google Scholar 

Hartzell HC, Fischmeister R (1987) Effect of forskolin and acetylcholine on calcium current in single isolated cardiac myocytes. Mol Pharmacol 32:639–645

Google Scholar 

Hille B (1967) The selective inhibition of delayed potassium currents in nerve by tetraethylammonium ion. J Gen Physiol 50:1287–1302

Google Scholar 

Hille B (1970) Ionic channels in nerve membranes. Prog Biophys Mol Biol 21:3–30

Google Scholar 

Hille B (1984) Ionic channels of excitable membranes. Sinauer

Google Scholar 

Hille B (2018) The founding of journal of general physiology: membrane permeation and ion selectivity. J Gen Physiol 150:389–400

Google Scholar 

Hodgkin AL (1964) The conduction of the nervous impulse. Liverpool University Press

Google Scholar 

Hodgkin AL, Huxley AF (1952) Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. J Physiol 116:449–472

Google Scholar 

Holst GL, Stoy W, Yang B, Kolb I, Kodandaramaiah SB, Li L, Knoblich U, Zeng H, Haider B, Boyden ES, Forest CR (2019) Autonomous patch-clamp robot for functional characterization of neurons in vivo: development and application to mouse visual cortex. J Neurophysiol 121:2341–2357

Google Scholar 

Horn R, Marty A (1988) Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145–159

Google Scholar 

Horn R, Patlak J (1980) Single channel currents from excised patches of muscle membrane. Proc Natl Acad Sci U S A 77:6930–6934

Google Scholar 

Hucho F, Changeux JP (1973) Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue. FEBS Lett 38:11–15

Google Scholar 

Huxley AF (2002) From overshoot to voltage clamp. Trends Neurosci 25:553–558

Google Scholar 

Jayant K, Wenzel M, Bando Y, Hamm JP, Mandriota N, Rabinowitz JH, Plante IJ, Owen JS, Sahin O, Shepard KL, Yuste R (2019) Flexible nanopipettes for minimally invasive intracellular electrophysiology in vivo. Cell Rep 26:266–278

Google Scholar 

Katz B (1966) Nerve, muscle, and synapse. McGraw-Hill

Google Scholar 

Katz B, Miledi R (1965) Propagation of electric activity in motor nerve terminals. Proc R Soc Lond Ser B Biol Sci 161:453–482

Google Scholar 

Katz B, Miledi R (1972) The statistical nature of the acetylcholine potential and its molecular components. J Physiol 224:665–699

Google Scholar 

Katz B, Miledi R (1979) Membrane noise produced by acetylcholine. Nature 226:962–963

Google Scholar 

Kodandaramaiah SB, Franzesi GT, Chow BY, Boyden ES, Forest CR (2012) Automated whole-cell patch-clamp electrophysiology of neurons in vivo. Nat Methods 9:585–587

Google Scholar 

Kodandaramaiah SB, Flores FJ, Holst GL, Singer AC, Han X, Brown EN, Boyden ES, Forest CR (2018) Multi-neuron intracellular recording in vivo via interacting autopatching robots. eLife 7:e24656

Google Scholar 

Kostyuk PG, Krishtal OA (1977) Effects of calcium and calcium-chelating agents on the inward and outward current in the membrane of mollusc neurones. J Physiol 270:569–580

Google Scholar 

Lamb TD, Simon EJ (1977) Analysis of electrical noise in turtle cones. J Physiol 272:435–468

Google Scholar 

Lambolez B, Audinat E, Bochet P, Crépel F, Rossier J (1992) AMPA receptor subunits expressed by single Purkinje cells. Neuron 9:247–258

Google Scholar 

Lassignal NL, Martin AR (1976) Reversal of acetylcholine potentials in eel electroplaque. Science 191:464–466

Google Scholar 

Lee AK, Manns ID, Sakmann B, Brecht M (2006) Whole-cell recordings in freely moving rats. Neuron 51:399–407

Google Scholar 

Lindau M, Neher E (1988) Patch-clamp techniques for time-resolved capacitance measurements in single cells. Pflugers Arch 411:137–146

Google Scholar 

Lombard J (2014) Once upon a time the cell membranes: 175 years of cell boundary research. Biol Direct 9:32

Google Scholar 

Luo Y, Shen W, Cline HT (2021) Electrophysiological recording for study of xenopus retinotectal circuitry. Cold Spring Harb Protoc. https://doi.org/10.1101/pdb.prot106880

Mak DO, Foskett JK (2015) Inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum: a single-channel point of view. Cell Calcium 58:67–78

Google Scholar 

Marty A, Finkelstein A (1975) Pores formed in lipid bilayer membranes by nystatin. Differences in its one-sided and two-sided action. J Gen Physiol 6:515–526

Google Scholar 

Minke B (2010) The history of the Drosophila TRP channel: the birth of a new channel superfamily. J Neurogenet 24:216–233

Google Scholar 

Minke B, Wu C, Pak WL (1975) Induction of photoreceptor voltage noise in the dark in Drosophila mutant. Nature 258:84–87

Google Scholar 

Moore JW, Naharashi T (1967) Tetrodotoxin’s highly selective blockage of an ionic channel. Fed Proc 26:1655–1663

Google Scholar 

Moore JW, Naharashi T, Shaw TI (1967) An upper limit to the number of sodium channels in nerve membrane? J Physiol 188:99–105

Google Scholar 

Mueller P, Rudin DO, Tien HT, Westcott WC (1962) Reconstitution of cell membrane structure in vitro and its transformation into an excitable system. Nature 194:979–980

Google Scholar 

Neher E, Lux HD (1969) Voltage clamp on Helix pomatia neuronal membrane; current measurement over a limited area of the soma surface. Pflugers Arch 311:272–277

Google Scholar 

Neher E, Lux HD (1971) Properties of somatic membrane patches of snail neurons under voltage clamp. Pflugers Arch 322:35–38

Google Scholar 

Neher E, Marty A (1982) Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells. Proc Natl Acad Sci U S A 79:6712–6716

Google Scholar 

Neher E, Sakmann B (1976) Single-channel currents recorded from membrane of denervated muscle fibers. Nature 260:799–802

Google Scholar 

Neher E, Stevens CF (1977) Conductance fluctuations and ionic pores in membranes. Annu Rev Biophys Bioeng 6:345–381

Google Scholar 

Neher E, Sakmann B, Steinbach JH (1978) The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes. Pflugers Arch 375:219–228

Google Scholar 

Neo Biosystems (n.d.). https://www.neobiosystems.com/PatchMAX100A.php

Neuromatic Devices (2021). https://neuromaticdevices.com/author/nd0913/

Nilius B (2003) Pflügers Archiv and the advent of modern electrophysiology. From the first action potential to patch clamp. Pflugers Arch 447:267–271

Google Scholar 

Noda M, Shimizu S, Tanabe T, Takai T, Kayano T, Ikeda T, Takahashi H, Nakayama H, Kanaoka H, Minamino N, Kangawa K et al (1984) Primary structure of electrophorus electricus sodium channel deduced from cDNA sequence. Nature 312:121–127

Google Scholar 

Obergrussberger A, Friis S, Brüggemann A, Fertig N (2021) Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade. Expert Opin Drug Discov 16:1–5

Google Scholar 

Reyes AD (2019) Neuronal signals thoroughly recorded. Nature 575:38–39

Google Scholar 

Rollenhagen A, Ohana O, Sätzler K, Hilgetag CC, Kuhl D, Lübke JHR (2018) Structural properties of synaptic transmission and temporal dynamics at excitatory layer 5B synapses in the adult rat somatosensory cortex. Front Synaptic Neurosci 10:24

Google Scholar 

Rosholm KR, Boddum K, Lindquist A (2021) Perforated whole-cell recordings in automated patch clamp electrophysiology. Methods Mol Biol 2188:93–108

Google Scholar 

Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, Arnheim N (1985) Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230:1350–1354

Google Scholar 

Sakmann B (2006) Patch pipettes are more useful than initially thought: simultaneous pre- and postsynaptic recording from mammalian CNS synapses in vitro and in vivo. Pflugers Arch 453:249–259

Google Scholar 

Sakmann B, Neher E (eds) (1983) Single-channel recording. Plenum Press

Google Scholar 

Santi MR, Vicini S, Eldadah B, Neale JH (1994) Analysis by polymerase chain reaction of alpha 1 and alpha 6 GABAA receptor subunit mRNAs in individual cerebellar neurons after whole-cell recordings. J Neurochem 63:2357–2360

Google Scholar 

Siegelbaum SA, Camardo JS, Kandel ER (1982) Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones. Nature 299:413–417

Google Scholar 

Sigworth FJ (1986) The patch clamp is more useful than anyone had expected. Fed Proc 45:2673–2677

Google Scholar 

Sigworth FJ (2010) Molecular switches for “animal electricity”, Chapter 15. In: Garwin L, Lincoln T (eds) A century of nature. University of Chicago Press, Chicago, pp 217–223

Google Scholar 

Sigworth FJ, Neher E (1980) Single Na+ channel currents observed in cultured rat muscle cells. Nature 287:447–449

Google Scholar 

Singer SJ, Nicolson GL (1972) The fluid mosaic model of the structure of cell membranes. Science 175:720–731

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