Acyclovir 1 Oral Acyclovir Urticaria 100 1 Intravenous Acyclovir Urticaria 101 1 Oral Acyclovir Maculopapular eruption and eczema 102 1 Oral Acyclovir Eczema 102 1 Oral Acyclovir Generalized symmetrical exanthem 103 Alprenolol 1 Oral Alprenolol Widespread dermatitis 104 Aminophyllinea 2 Intravenous Ethylenediamine SDRIFE/baboon syndrome 105, 106 2 Oral Ethylenediamine Lichenoid eruption 107 1 Intravenous Ethylenediamine Generalized dermatitis 108 1 Intramuscular Ethylenediamine Erythroderma 108 1 Oral Ethylenediamine Erythematous eruption 109 1 Oral Ethylenediamine Exfoliative erythroderma 110 1 Oral Ethylenediamine Maculopapular eruption 111 1 Intravenousb Ethylenediamine Maculopapular eruption 111 1 Suppository Ethylenediamine Exfoliative erythroderma 112 1 Suppository Ethylenediamine Generalized eruption of erythematous papules 113 Amlexanox 1 Oral Amlexanox Erythema multiforme-like eruption 114 Amoxicillin 1 Oral Topical penicillin SDRIFE/baboon syndrome 115c Bacampicillin 1 Oralb Bacampicillind Hand eczema, relapse of positive patch test, stomach pain, diarrhoea 116 Betamethasone 2 Oral Betamethasone/other CSs SDRIFE/baboon syndrome 117, 118b 1 Oral Hydrocortisone Facial erythema 119 1 Oral Triamcinolone acetonide Generalized papular dermatitis 97 Betamethasone acetate 1 Intralesionalb Hydrocortisone Facial erythema 119 Betamethasone dipropionate 1 Intramuscular Unknown corticosteroid(s) Maculopapular exanthema + flare-up 120 1 Intra-articular Unknown corticosteroid(s) Generalized eczema, flare-up of previous eczema 120 1 Intramuscular Unknown corticosteroid(s) Unknown exanthema 120 Betamethasone sodium phosphate 1 Intralesionalb Hydrocortisone Facial erythema 119 1 Intramuscular Unknown corticosteroid(s) Maculopapular exanthema + flare-up 120 1 Intra-articular Unknown corticosteroid(s) Generalized eczema, flare-up of previous eczema 120 1 Intramuscular Unknown corticosteroid(s) Unknown exanthema 120 Carbutamide 7 Oralb Sulfanilamide Relapse of dermatitis and previous patch test 121c Cefalexin 1 Oral Cefalexin Generalized itching, erythema, scaling 122 Chloral hydrate 2 Oral & oralb Chloral hydrate “Eruption” 123 Chloramphenicol 1 Intramuscular Chloramphenicol Edematous and exudative reaction of the face 54 Chlorpheniramine 2 “Injection” Dexchlorpheniramine Generalized dermatitis 124 Chlorpromazine 2 Oral Promethazine Exacerbation of previous dermatitis 125 1 Oral Chlorpromazine Oedema of the hands, arms and face, vertigo, tendency to fainting 125 Chlorpropamide 1 Oralb Sulfanilamide Relapse of dermatitis and patch test 121c Chlorquinaldol See under Clioquinol Clioquinol 6 Oralb Clioquinol Flare-up of original dermatitis (n = 5); scattered papules (n = 2); localized itching (n = 2), generalized papular dermatitis (n = 1); some patients were sensitized to clioquinol, others to chlorquinaldol; some were orally challenged with one drug, some with the other; these were treated as one group, no differentiating data were provided 126 2 Oral Clioquinol Generalized dermatitis 127, 128 1 Oral Clioquinol Flare-up of previous dermatitis 129c Clonidine 1 Oralb Clonidine Flare-up of previous dermatitis 130 1 Oralb Clonidine Maculopapular eruption 130 Cloprednol 1 Oralb Unknown corticosteroid(s) SDRIFE/baboon syndrome 118 Codeinee ? Codeine or other opium alkaloids Various manifestations of systemic allergic dermatitis 131-136 Cyanocobalamin 1 Oral Cobalt Widespread nummular and hand dermatitis 137 Deflazacort 1 Oral Three other CSs Maculopapular eruption 138 1 Oral Unknown corticosteroid(s) Erythematous plaques with pustules 139 1 Oral Deflazacortd SDRIFE/baboon syndrome with fever, nausea, vomiting, and hypotension 140 1 Oralb 8 other corticosteroids Pruritic rash on the forearms and chest 141c 1 Oral Betamethasone valerate Dermatitis on the arms and legs 142 Dexamethasone 1 Oralb Unknown corticosteroid(s) Maculopapular exanthema 143 1 Oralb Unknown corticosteroid(s) SDRIFE/baboon syndrome 118c Dexamethasone disodium phosphate 1 Oral 3 other corticosteroids Maculopapular eruption 138 Dexketoprofenf 1 Oral Ketoprofen Systemic photoallergic dermatitis 144 Dimethindene 1 Oral Dimethindene Maculopapular and vesicular rash 145 Dimethyl sulfoxide 1 Intravesical Dimethyl sulfoxide Erythematous micropapular eruption 146 Diphenhydramine 1 Oral Diphenhydramine Generalized dermatitis 147 1 Oral Diphenhydramine Systemic photoallergic dermatitis (uncertain) 148 1 Oral Diphenhydramine Unknown exanthema 149 Disulfiram 1 Oral Disulfiram (rubber) Erythematous scaly rash, fever, vomiting 150 1 Oral Disulfiram (implant) Dyshidrotic eczema, nummular eczema 151 1 Oral Disulfiram (rubber) Generalized dermatitis 152 1 Oral Disulfiram (implant) Erythema and oedema of the face, widespread erythematous, oedematous and vesicular patches and an urticarial plaque around the operation scar of a previous disulfiram implant (removed because it was “inflamed”)

151, 153

1 Oral Disulfiram (rubber) Erythematous and vesicular dermatitis 154 1 Oral Disulfiram (rubber) Violent reaction with widespread skin rash 155 1 Oral Disulfiram (implant) Generalized dermatitis 156 1 Oral Disulfiram (rubber) Oedema of the feet + vesicular rash face, arms, and dorsal feet 157 Doxepin 1 Oral Doxepin Extensive scaly patches and plaques 158 Ephedrine 3 Oral Ephedrine Generalized erythema 159, 160 Epirubicin 1 Intravesical Mitomycin C (uncertain) Widespread dermatitis (uncertain case) 161 Erythromycin 1 Oral Erythromycin Generalized dermatitis 162, 163 Estradiol 1 Oral Estradiol Systemic pruritic rash 164 2 Oral Estradiol Maculopapular eruptions 165 Estradiol derivative