PACAP38- and VIP-induced cluster headache attacks are not associated with changes of plasma CGRP or markers of mast cell activation

1. Headache Classification Committee of the International Headache Society . The International Classification of Headache Disorders, 3rd edition. Cephalalgia 2018; 38: 1–211.
Google Scholar2. Hoffmann, J, May, A. Diagnosis, pathophysiology, and management of cluster headache. Lancet Neurol 2018; 17: 75–83.
Google Scholar | Crossref | Medline3. Vaudry, D, Gonzalez, BJ, Basille, M, et al . Pituitary adenylate cyclase-activating polypeptide and its receptors: From structure to functions. Pharmacol Rev 2000; 52: 269–324.
Google Scholar | Medline | ISI4. Vollesen, ALH, Snoer, A, Chaudhry, B, et al. The effect of pituitary adenylate cyclase-activating peptide-38 and vasoactive intestinal peptide in cluster headache. Cephalalgia 2020; 40: 1474–1488.
Google Scholar | SAGE Journals | ISI5. Vollesen, ALH, Snoer, A, Beske, RP, et al. Effect of infusion of calcitonin gene-related peptide on cluster headache attacks: A randomized clinical trial. JAMA Neurol 2018; 75: 1187–1197.
Google Scholar | Crossref | Medline6. Goadsby, PJ, Dodick, DW, Leone, M, et al. Trial of galcanezumab in prevention of episodic cluster headache. N Engl J Med 2019; 381: 132–141.
Google Scholar | Crossref | Medline7. Horton, BT, MacLean, AR, Craig, WM. A new syndrome of vascular headache: Results of treatment with histamine. Preliminary report. Proc Mayo Clin 1939; 14: 257–260.
Google Scholar8. Wiesner-Menzel, L, Schulz, B, Varkilzadeh, F, et al. Electron microscopical evidence for a direct contact between nerve fibres and mast cells. Acta Dem Venereol (Stockh) 1981; 61: 465–469.
Google Scholar | Medline | ISI9. Dimitriadou, V, Aubineau, P, Taxi, J, et al. Ultra-structural evidence for a functional unit between nerve fibers and type II mast cells in the cerebral vascular wall. Neuroscience 1987; 22: 621–630.
Google Scholar | Crossref | Medline | ISI10. Fantozzi, R, Masini, E, Blandina, P, et al. Release of histamine from rat mast cells by acetylcholine. Nature 1978; 273: 473–474.
Google Scholar | Crossref | Medline11. Reynier-Rebuffel, AM, Callebert, J, Dimitriadou, V, et al. Carbachol induces granular cell exocytosis and serotonin release in rabbit cerebral arteries. Am J Physiol 1992; 262: R105–R111.
Google Scholar | Medline | ISI12. Dimitriadou, V, Henry, P, Brochet, B, et al. Cluster headache: Ultrastructural evidence for mast cell degranulation and interaction with nerve fibers in the human temporal artery. Cephalalgia 1990; 10: 221–228.
Google Scholar | SAGE Journals | ISI13. Appenzeller, O, Becker, WJ, Ragaz, A. Cluster headache. Ultrastructural aspects and pathogenic mechanisms. Arch Neurol 1981; 38: 302–306.
Google Scholar | Crossref | Medline14. Liberski, PP, Mirecka, B. Mast cells in cluster headache. Ultrastructure, release pattern and possible pathogenic significance. Cephalalgia 1984; 4: 101–106.
Google Scholar | SAGE Journals | ISI15. Headache Classification Committee of the International Headache Society (IHS) . The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013; 33: 629–808.
Google Scholar | SAGE Journals | ISI16. Schifter, S. Circulating concentrations of calcitonin gene-related peptide (CGRP) in normal man determined with a new, highly sensitive radioimmunoassay. Peptides 1991; 12: 365–369.
Google Scholar | Crossref | Medline | ISI17. Snoer, A, Vollesen, ALH, Beske, RP, et al. Calcitonin-gene related peptide and disease activity in cluster headache. Cephalalgia 2019; 39: 575–584.
Google Scholar | SAGE Journals | ISI18. Goadsby, PJ, Edvinsson, L. Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute attacks therapies. Brain 1994; 117: 427–434.
Google Scholar | Crossref | Medline | ISI19. Fanciullacci, M, Alessandri, M, Figini, M, et al. Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack. Pain 1995; 60: 119–123.
Google Scholar | Crossref | Medline | ISI20. Fanciullacci, M, Alessandri, M, Sicuteri, R, et al. Responsiveness of the trigeminovascular system to nitroglycerine in cluster headache patients. Brain 1997; 120: 283–288.
Google Scholar | Crossref | Medline | ISI21. Guo, S, Vollesen, AL, Hansen, YB, et al. Part II: Biochemical changes after pituitary adenylate cyclase-activating polypeptide-38 infusion in migraine patients. Cephalalgia 2017; 37: 136–147.
Google Scholar | SAGE Journals | ISI22. Jansen-Olesen, I, Baun, M, Amrutkar, DV, et al. PACAP-38 but not VIP induces release of CGRP from trigeminal nucleus caudalis via a receptor distinct from the PAC1 receptor. Neuropeptides 2014; 48: 53–64.
Google Scholar | Crossref | Medline | ISI23. Németh, J, Reglödi, D, Pozsgai, G, et al. Effect of pituitary adenylate cyclase activating polypeptide-38 on sensory neuropeptide release and neurogenic inflammation in rats and mice. Neuroscience 2006; 143: 223–230.
Google Scholar | Crossref | Medline | ISI24. Schwartz, LB, Metcalfe, DD, Miller, JS, et al. Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis. N Engl J Med 1987; 316: 1622–1626.
Google Scholar | Crossref | Medline25. Steinhoff, M, Vergnolle, N, Young, SH, et al. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med 2000; 6: 151–158.
Google Scholar | Crossref | Medline | ISI26. Hassler, SN, Ahmad, FB, Burgos-Vega, CC, et al. Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice. Cephalalgia 2019; 39: 111–122.
Google Scholar | SAGE Journals | ISI27. Anthony, M, Lance, JW. Histamine and serotonin in cluster headache. Arch Neurol 1971; 25: 225–231.
Google Scholar | Crossref | Medline28. Medina, JL, Diamond, S, Fareed, J. The nature of cluster headache. Headache 1979; 19: 309–322.
Google Scholar | Crossref | Medline | ISI29. Russell, D. Cluster headache: Trial of combined histamine H1 and H2 antagonist treatment. J Neurol Neurosurg Psychiatry 1979; 42: 668–669.
Google Scholar | Crossref | Medline | ISI30. Veger, T, Russell, D, Sjaastad, O. Histamine H2 antagonists and cluster headache. Br Med J 1976; 2: 585.
Google Scholar | Crossref | Medline31. Cuypers, J, Altenkirch, H, Bunge, S. Therapy of cluster headache with histamine H1 and H2 receptor antagonists. Eur Neurol 1979; 18: 345–347.
Google Scholar | Crossref | Medline | ISI32. Amin, FM, Hougaard, A, Schytz, HW, et al. Investigation of the pathophysiological mechanisms of migraine attacks induced by pituitary adenylate cyclase-activating polypeptide-38. Brain 2014; 137: 779–794.
Google Scholar | Crossref | Medline | ISI33. Kopruszinski, CM, Thornton, P, Arnold, J, et al. Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine. Cephalalgia 2020; 40: 1535–1550.
Google Scholar | SAGE Journals | ISI34. Day, SJ, Graham, DF. Sample size and power for comparing two or more treatment groups in clinical trials. BMJ 1989; 299: 663–665.
Google Scholar | Crossref | Medline35. Zaidi, M, Bevis, PJ, Girgis, SI, et al. Circulating CGRP comes from the perivascular nerves. Eur J Pharmacol 1985; 117: 283–284.
Google Scholar | Crossref | Medline36. Risch, M, Vogler, B, Dux, M, et al. CGRP outflow into jugular blood and cerebrospinal fluid and permeance for CGRP of rat dura mater. J Headache Pain 2021; 22: 105.
Google Scholar | Crossref | Medline37. Roderick JL, et al. The prevention and treatment of missing data in clinical trials. N Engl J Med 2012; 367: 1355–1360.
Google Scholar38. White, IR, Carlin, JB. Bias and efficiency of multiple imputation compared with complete-case analysis for missing covariate values. Stat Med 2010; 29: 2920–2931.
Google Scholar | Crossref | Medline | ISI

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