Periodontitis Salivary Microbiota Worsens Colitis

Ahluwalia, B, Moraes, L, Magnusson, MK, Öhman, L. 2018. Immunopathogenesis of inflammatory bowel disease and mechanisms of biological therapies. Scand J Gastroenterol. 53(4):379–389.
Google Scholar | Crossref | Medline Arimatsu, K, Yamada, H, Miyazawa, H, Minagawa, T, Nakajima, M, Ryder, MI, Gotoh, K, Motooka, D, Nakamura, S, Iida, T, et al. 2014. Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota. Sci Rep. 4(1):4828.
Google Scholar | Crossref | Medline Atarashi, K, Suda, W, Luo, C, Kawaguchi, T, Motoo, I, Narushima, S, Kiguchi, Y, Yasuma, K, Watanabe, E, Tanoue, T, et al. 2017. Ectopic colonization of oral bacteria in the intestine drives T(H)1 cell induction and inflammation. Science. 358(6361):359–365.
Google Scholar | Crossref | Medline Axelrad, JE, Cadwell, KH, Colombel, JF, Shah, SC. 2020. Systematic review: gastrointestinal infection and incident inflammatory bowel disease. Aliment Pharmacol Ther. 51(12):1222–1232.
Google Scholar | Crossref | Medline Benítez-Páez, A, Gómez Del Pugar, EM, López-Almela, I, Moya-Pérez, Á, Codoñer-Franch, P, Sanz, Y. 2020. Depletion of blautia species in the microbiota of obese children relates to intestinal inflammation and metabolic phenotype worsening. mSystems. 5(2):e00857-19.
Google Scholar | Crossref | Medline Brito, F, Zaltman, C, Carvalho, AT, Fischer, RG, Persson, R, Gustafsson, A, Figueredo, CM. 2013. Subgingival microflora in inflammatory bowel disease patients with untreated periodontitis. Eur J Gastroenterol Hepatol. 25(2):239–245.
Google Scholar | Crossref | Medline Britton, GJ, Contijoch, EJ, Mogno, I, Vennaro, OH, Llewellyn, SR, Ng, R, Li, Z, Mortha, A, Merad, M, Das, A, et al. 2019. Microbiotas from humans with inflammatory bowel disease alter the balance of gut Th17 and RORγt(+) regulatory T cells and exacerbate colitis in mice. Immunity. 50(1):212–224.e4.
Google Scholar | Crossref | Medline Chassaing, B, Aitken, JD, Malleshappa, M, Vijay-Kumar, M. 2014. Dextran sulfate sodium (DSS)–induced colitis in mice. Curr Protoc Immunol. 104:15.25.1–15.25.14.
Google Scholar | Crossref | Medline Fine, N, Chadwick, JW, Sun, C, Parbhakar, KK, Khoury, N, Barbour, A, Goldberg, M, Tenenbaum, HC, Glogauer, M. 2021. Periodontal inflammation primes the systemic innate immune response. J Dent Res. 100(3):318–325.
Google Scholar | SAGE Journals | ISI Gevers, D, Kugathasan, S, Denson, L, Vázquez-Baeza, Y, Van Treuren, W, Ren, B, Schwager, E, Knights, D, Song, S, Yassour, M, et al. 2014. The treatment-naive microbiome in new-onset crohn’s disease. Cell Host Microbe. 15(3):382–392.
Google Scholar | Crossref | Medline Gonzalez Acera, M, Patankar, JV, Diemand, L, Siegmund, B, Neurath, MF, Wirtz, S, Becker, C. 2021. Comparative transcriptomics of IBD patients indicates induction of type 2 immunity irrespective of the disease ideotype. Front Med. 8:664045.
Google Scholar | Crossref Habashneh, RA, Khader, YS, Alhumouz, MK, Jadallah, K, Ajlouni, Y. 2012. The association between inflammatory bowel disease and periodontitis among jordanians: a case-control study. J Periodontal Res. 47(3):293–298.
Google Scholar | Crossref | Medline Hajishengallis, G, Chavakis, T. 2021. Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities. Nat Rev Immunol. 21(7):426–440.
Google Scholar | Crossref | Medline Hooper, LV, Littman, DR, Macpherson, AJ. 2012. Interactions between the microbiota and the immune system. Science. 336(6086):1268–1273.
Google Scholar | Crossref | Medline | ISI Jain, U, Ver Heul, AM, Xiong, S, Gregory, MH, Demers, EG, Kern, JT, Lai, CW, Muegge, BD, Barisas, DAG, Leal-Ekman, JS, et al. 2021. Debaryomyces is enriched in Crohn’s disease intestinal tissue and impairs healing in mice. Science. 371(6534):1154–1159.
Google Scholar | Crossref | Medline Jiang, X, Yang, S, Sun, G. 2013. Odontogenic infection due to Aerococcus viridans: a case report. J Oral Maxillofac Surg. 71(9):1552–1554.
Google Scholar | Crossref | Medline Kato, T, Yamazaki, K, Nakajima, M, Date, Y, Kikuchi, J, Hase, K, Ohno, H, Yamazaki, K. 2018. Oral administration of porphyromonas gingivalis alters the gut microbiome and serum metabolome. mSphere. 3(5):e00460-18.
Google Scholar | Crossref | Medline Kitamoto, S, Nagao-Kitamoto, H, Hein, R, Schmidt, TM, Kamada, N. 2020. The bacterial connection between the oral cavity and the gut diseases. J Dent Res. 99(9):1021–1029.
Google Scholar | SAGE Journals | ISI Kitamoto, S, Nagao-Kitamoto, H, Jiao, Y, Gillilland, MG, Hayashi, A, Imai, J, Sugihara, K, Miyoshi, M, Brazil, JC, Kuffa, P, et al. 2020. The intermucosal connection between the mouth and gut in commensal pathobiont-driven colitis. Cell. 182(2):447–462.e14.
Google Scholar | Crossref | Medline Kuo, CH, Ko, YC, Yang, SN, Chu, YT, Wang, WL, Huang, SK, Chen, HN, Wei, WJ, Jong, YJ, Hung, CH. 2011. Effects of PGI2 analogues on Th1- and Th2-related chemokines in monocytes via epigenetic regulation. J Mol Med. 89(1):29–41.
Google Scholar | Crossref | Medline Li, WJ, Lu, JW, Zhang, CY, Wang, WS, Ying, H, Myatt, L, Sun, K. 2020. PGE2 vs PGF2α in human parturition. Placenta. 104:208–219.
Google Scholar | Crossref | Medline Lin, S, Li, Y, Shen, L, Zhang, R, Yang, L, Li, M, Li, K, Fichna, J. 2017. The anti-inflammatory effect and intestinal barrier protection of HU210 differentially depend on TLR4 signaling in dextran sulfate sodium–induced murine colitis. Dig Dis Sci. 62(2):372–386.
Google Scholar | Crossref | Medline Miyoshi, H, VanDussen, KL, Malvin, NP, Ryu, SH, Wang, Y, Sonnek, NM, Lai, CW, Stappenbeck, TS. 2017. Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium. EMBO J. 36(1):5–24.
Google Scholar | Crossref | Medline Na, YR, Stakenborg, M, Seok, SH, Matteoli, G. 2019. Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD. Nat Rev Gastroenterol Hepatol. 16(9):531–543.
Google Scholar | Crossref | Medline Nakajima, M, Arimatsu, K, Kato, T, Matsuda, Y, Minagawa, T, Takahashi, N, Ohno, H, Yamazaki, K. 2015. Oral administration of P. gingivalis induces dysbiosis of gut microbiota and impaired barrier function leading to dissemination of enterobacteria to the liver. PLoS One. 10(7):e0134234.
Google Scholar | Crossref Orecchioni, M, Ghosheh, Y, Pramod, AB, Ley, K. 2019. Macrophage polarization: different gene signatures in M1(LPS+) vs. classically and M2(LPS−) vs. alternatively activated macrophages. Front Immunol. 10:1084.
Google Scholar | Crossref | Medline Pietropaoli, D, Del Pinto, R, Corridoni, D, Rodriguez-Palacios, A, Di Stefano, G, Monaco, A, Weinberg, A, Cominelli, F. 2014. Occurrence of spontaneous periodontal disease in the SAMP1/YitFc murine model of Crohn disease.J Periodontol. 85(12):1799–1805.
Google Scholar | Crossref | Medline Pochard, C, Gonzales, J, Bessard, A, Mahe, MM, Bourreille, A, Cenac, N, Jarry, A, Coron, E, Podevin, J, Meurette, G, et al. 2021. PGI2 inhibits intestinal epithelial permeability and apoptosis to alleviate colitis. Cell Mol Gastroenterol Hepatol. 12(3):1037–1060.
Google Scholar | Crossref | Medline Qi, Y, Zang, SQ, Wei, J, Yu, HC, Yang, Z, Wu, HM, Kang, Y, Tao, H, Yang, MF, Jin, L, et al. 2021. High-throughput sequencing provides insights into oral microbiota dysbiosis in association with inflammatory bowel disease. Genomics. 113(1 Pt 2):664–676.
Google Scholar | Crossref | Medline Rasmussen, M . 2016. Aerococcus: an increasingly acknowledged human pathogen. Clin Microbiol Infect. 22(1):22–27.
Google Scholar | Crossref | Medline Rehal, S, von der Weid, PY. 2015. Experimental ileitis alters prostaglandin biosynthesis in mesenteric lymphatic and blood vessels. Prostaglandins Other Lipid Mediat. 116– 117:37–48.
Google Scholar Said, HS, Suda, W, Nakagome, S, Chinen, H, Oshima, K, Kim, S, Kimura, R, Iraha, A, Ishida, H, Fujita, J, et al. 2014. Dysbiosis of salivary microbiota in inflammatory bowel disease and its association with oral immunological biomarkers. DNA Res. 21(1):15–25.
Google Scholar | Crossref | Medline Sato, K, Takahashi, N, Kato, T, Matsuda, Y, Yokoji, M, Yamada, M, Nakajima, T, Kondo, N, Endo, N, Yamamoto, R, et al. 2017. Aggravation of collagen-induced arthritis by orally administered Porphyromonas gingivalis through modulation of the gut microbiota and gut immune system. Sci Rep. 7(1):6955.
Google Scholar | Crossref | Medline Schirmer, M, Garner, A, Vlamakis, H, Xavier, RJ. 2019. Microbial genes and pathways in inflammatory bowel disease. Nat Rev Microbiol. 17(8):497–511.
Google Scholar | Crossref | Medline She, YY, Kong, XB, Ge, YP, Liu, ZY, Chen, JY, Jiang, JW, Jiang, HB, Fang, SL. 2020. Periodontitis and inflammatory bowel disease: a meta-analysis. BMC Oral Health. 20(1):67.
Google Scholar | Crossref | Medline Shi, Y, Liu, Z, Cui, X, Zhao, Q, Liu, T. 2020. Intestinal vitamin D receptor knockout protects from oxazolone-induced colitis. Cell Death Dis. 11(6):461.
Google Scholar | Crossref | Medline Somineni, H, Weitzner, J, Venkateswaran, S, Dodd, A, Prince, J, Karikaran, A, Sauer, C, Abramowicz, S, Zwick, M, Cutler, D, et al. 2021. Site- and taxa-specific disease-associated oral microbial structures distinguish inflammatory bowel diseases. Inflamm Bowel Dis [epub ahead of print 14 May 2021] in press. doi:10.1093/ibd/izab082
Google Scholar | Crossref | Medline Tsuzuno, T, Takahashi, N, Yamada-Hara, M, Yokoji-Takeuchi, M, Sulijaya, B, Aoki-Nonaka, Y, Matsugishi, A, Katakura, K, Tabeta, K, Yamazaki, K. 2021. Ingestion of Porphyromonas gingivalis exacerbates colitis via intestinal epithelial barrier disruption in mice. J Periodontal Res. 56(2):275–288.
Google Scholar | Crossref | Medline Wang, J, Chen, WD, Wang, YD. 2020. The relationship between gut microbiota and inflammatory diseases: the role of macrophages. Front Microbiol. 11:1065.
Google Scholar | Crossref | Medline Yachida, S, Mizutani, S, Shiroma, H, Shiba, S, Nakajima, T, Sakamoto, T, Watanabe, H, Masuda, K, Nishimoto, Y, Kubo, M, et al. 2019. Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer. Nat Med. 25(6):968–976.
Google Scholar | Crossref | Medline Zhang, Y, Qiao, D, Chen, R, Zhu, F, Gong, J, Yan, F. 2021. The association between periodontitis and inflammatory bowel disease: a systematic review and meta-analysis. Biomed Res Int. 2021:6692420.
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