Identification of Hub Genes Related to Alzheimer’s Disease and Major Depressive Disorder

1. Association, As. . Alzheimer's disease facts and figures. Alzheimers Dement. 2016;12(4):459-509. 10.1016/j.jalz.2016.03.001.
Google Scholar | Crossref | Medline2. ADI. World . Alzheimer Report 2019: Attitudes to dementia. London: Alzheimer’s Disease International; 2019.
Google Scholar | Crossref3. Patnode, CD, Perdue, LA, Rossom, RC, et al. Rockville (MD): Agency for Healthcare Research and Quality (US). Screening for Cognitive Impairment in Older Adults: An Evidence Update for the U.S. Preventive Services Task Force [Internet]. 2020 Feb. Report No.: 19-05257-EF-1. PMID: 32129963
Google Scholar4. Mullard, A . FDA approval for Biogen's aducanumab sparks Alzheimer disease firestorm. Nat Rev Drug Discov. 2021. .1038/d41573-021-00099-3.
Google Scholar5. Disease, GBD . Injury i, prevalence c. global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the global burden of disease Study 2017. Lancet. Nov 10 2018;392(10159):1789-1858. 10.1016/S0140-6736(18)32279-7.
Google Scholar | Crossref | Medline6. Chisholm, D . Investing in mental health. E Mediterr Health J. 2015;21(7):531-534.
Google Scholar | Crossref | Medline7. Malhi, GS, Mann, JJ. Depression. Lancet. Nov. 2018;24(10161):2299-2312. 10.1016/S0140-6736(18)31948-2.
Google Scholar | Crossref8. Kendler, KS, Gatz, M, Gardner, CO, Pedersen, NL. A swedish national twin study of lifetime major depression. Am J Psychiatry. 2006;163(1):109-114. 10.1176/appi.ajp.163.1.109.
Google Scholar | Crossref | Medline | ISI9. Galts, CPC, Bettio, LEB, Jewett, DC, et al.. Depression in neurodegenerative diseases: Common mechanisms and current treatment options. Neurosci Biobehav Rev. Jul. 2019;102:56-84. doi:10.1016/j.neubiorev.2019.04.002.
Google Scholar | Crossref | Medline10. Jahangir, S, Adjepong, D, Al-Shami, HA, Malik, BH. Is there an association between migraine and major depressive disorder? A narrative review. Cureus. 2020;12(6):e8551. 10.7759/cureus.8551.
Google Scholar | Crossref | Medline11. Mugge, L, Mansour, TR, Crippen, M, Alam, Y, Schroeder, J. Depression and glioblastoma, complicated concomitant diseases: a systemic review of published literature. Neurosurg Rev. Apr. 2020;43(2):497-511. 10.1007/s10143-018-1017-2.
Google Scholar | Crossref | Medline12. Zhao, QF, Tan, L, Wang, HF, et al.. The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta-analysis. J Affect Disord. 2016;190:264-271. 10.1016/j.jad.2015.09.069.
Google Scholar | Crossref | Medline13. Petersen, JD, Waldorff, FB, Siersma, VD, Phung, TKT, Bebe, A, Waldemar, G. Major depressive symptoms Increase 3-Year mortality rate in patients with mild dementia. Int J Alzheimer's Dis. 2017;2017:7482094. 10.1155/2017/7482094.
Google Scholar | Crossref | Medline14. Davydow, DS, Zivin, K, Katon, WJ, et al.. Neuropsychiatric disorders and potentially preventable hospitalizations in a prospective cohort study of older Americans. J Gen Intern Med. Oct. 2014;29(10):1362-1371. 10.1007/s11606-014-2916-8.
Google Scholar | Crossref | Medline15. Lara, E, Haro, JM, Tang, MX, Manly, J, Stern, Y. Exploring the excess mortality due to depressive symptoms in a community-based sample: the role of Alzheimer's disease. J Affect Disord. 2016;202:163-170. 10.1016/j.jad.2016.05.057.
Google Scholar | Crossref | Medline16. Reus, GZ, Titus, SE, Abelaira, HM, et al.. Neurochemical correlation between major depressive disorder and neurodegenerative diseases. Life Sci. 2016;158:121-129. 10.1016/j.lfs.2016.06.027.
Google Scholar | Crossref | Medline17. Green, RC, Cupples, LA, Kurz, A, et al.. Depression as a risk factor for Alzheimer disease - The MIRAGE study. Arch Neurol-Chicago. 2003;60(5):753-759. 10.1001/archneur.60.5.753.
Google Scholar | Crossref | Medline18. Vermeulen, T, Lauwers, T, Van Diermen, L, Sabbe, BG, van der Mast, RC, Giltay, EJ. Cognitive deficits in older adults With psychotic depression: a meta-analysis. Am J Geriatr Psychiatry. 2019;27(12):1334-1344. 10.1016/j.jagp.2019.07.011.
Google Scholar | Crossref | Medline19. Steinberg, M, Shao, H, Zandi, P, et al.. Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry. 2008;23(2):170-177. 10.1002/gps.1858.
Google Scholar | Crossref | Medline | ISI20. Nowakowska, E, Kus, K, Chodera, A. Comparison of behavioural effects of venlafaxine and imipramine in rats. Arzneimittelforschung. 2003;53(4):237-242. 10.1055/s-0031-1297102.
Google Scholar | Crossref | Medline21. Peng, WF, Bai, F, Shao, K, Shen, LS, Li, HH, Huang, S. The key genes underlying pathophysiology association between the type 2-diabetic and colorectal cancer. J Cell Physiol. 2018;233(11):8551-8557. 10.1002/jcp.26440.
Google Scholar | Crossref | Medline22. Ritchie, ME, Phipson, B, Wu, D, et al.. Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 2015;43(7):e47. 10.1093/nar/gkv007.
Google Scholar | Crossref | Medline | ISI23. Li, MX, Jin, LT, Wang, TJ, et al.. Identification of potential core genes in triple negative breast cancer using bioinformatics analysis. Onco Targets Ther. 2018;11:4105-4112. 10.2147/OTT.S166567.
Google Scholar | Crossref | Medline24. Lin, SM, Wang, XJ, Huang, SH, et al.. Construction of artificial neural network model for predicting the efficacy of first-line FOLFOX chemotherapy for metastatic colorectal cancer. Zhonghua Zhong Liu Za Zhi. 2021;43(2):202-206. 10.3760/cma.j.cn112152-20200419-00355.
Google Scholar | Crossref | Medline25. Zhu, Y, Ding, X, She, Z, et al.. Exploring shared pathogenesis of Alzheimer's disease and type 2 diabetes mellitus via co-expression networks analysis. Curr Alzheimer Res. 2020;17(6):566-575. 10.2174/1567205017666200810164932.
Google Scholar | Crossref | Medline26. Szklarczyk, D, Gable, AL, Lyon, D, et al.. STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. Nucleic Acids Res. 2019;47(D1):D607-D613. 10.1093/nar/gky1131.
Google Scholar | Crossref | Medline27. Wang, J, Wang, Y, Kong, F, et al.. Identification of a six-gene prognostic signature for oral squamous cell carcinoma. J Cell Physiol. 2020;235(3):3056-3068. 10.1002/jcp.29210.
Google Scholar | Crossref | Medline28. Chin, CH, Chen, SH, Wu, HH, Ho, CW, Ko, MT, Lin, CY. cytoHubba: identifying hub objects and sub-networks from complex interactome. BMC Syst Biol. 2014;8(Suppl 4):S11. 10.1186/1752-0509-8-S4-S11.
Google Scholar | Crossref | Medline29. Luan, H, Zhang, C, Zhang, T, He, Y, Su, Y, Zhou, L. Identification of key prognostic biomarker and Its correlation with immune infiltrates in Pancreatic Ductal Adenocarcinoma. Dis Markers. 2020;2020:8825997. 10.1155/2020/8825997.
Google Scholar | Crossref | Medline30. Devarbhavi, P, Telang, L, Vastrad, B, Tengli, A, Vastrad, C, Kotturshetti, I. Identification of key pathways and genes in polycystic ovary syndrome via integrated bioinformatics analysis and prediction of small therapeutic molecules. Reprod Biol Endocrinol. 2021;19(1):31. 10.1186/s12958-021-00706-3.
Google Scholar | Crossref | Medline31. Otte, C, Gold, SM, Penninx, BW, et al.. Major depressive disorder. Nat Rev Dis Primers. 2016;2:16065. 10.1038/nrdp.2016.65.
Google Scholar | Crossref | Medline | ISI32. Yatawara, C, Lim, L, Chander, R, Zhou, J, Kandiah, N. Depressive symptoms influence global cognitive impairment indirectly by reducing memory and executive function in patients with mild cognitive impairment. J Neurol Neurosurg Psychiatry. 2016;87(12):1375-1383. 10.1136/jnnp-2016-314191.
Google Scholar | Crossref | Medline33. Kaup, AR, Byers, AL, Falvey, C, et al.. Trajectories of depressive symptoms in older adults and risk of dementia. JAMA Psychiatry. 2016;73(5):525-531. 10.1001/jamapsychiatry.2016.0004.
Google Scholar | Crossref | Medline34. Ma, G, Liu, M, Du, K, et al.. Differential expression of mRNAs in the brain tissues of patients with alzheimer's disease based on GEO expression profile and its clinical significance. BioMed Res Int. 2019;2019:8179145. 10.1155/2019/8179145.
Google Scholar | Crossref | Medline35. Daviglus, ML, Bell, CC, Berrettini, W, et al.. National institutes of health state-of-the-science conference statement: preventing alzheimer disease and cognitive decline. Ann Intern Med. 2010;153(3):176-181. 10.7326/0003-4819-153-3-201008030-00260.
Google Scholar | Crossref | Medline | ISI36. Deibel, SH, Young, B, Mohajerani, MH, McDonald, RJ. Activity rhythms are largely intact in APPNL-G-F alzheimer's disease mice. J Alzheimers Dis. 2019;71(1):213-225. 10.3233/JAD-190102.
Google Scholar | Crossref | Medline37. Spulber, S, Conti, M, Elberling, F, et al.. Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids. Transl Psychiatry. 2019;9(1):263. 10.1038/s41398-019-0594-3.
Google Scholar | Crossref | Medline38. Sarrouilhe, D, Mesnil, M, Dejean, C. Targeting gap junctions: new insights into the treatment of major depressive disorder. Curr Med Chem. 2019;26(20):3775-3791. 10.2174/0929867325666180327103530.
Google Scholar | Crossref | Medline39. He, JT, Li, XY, Yang, L, Zhao, X. Astroglial connexins and cognition: memory formation or deterioration?. Biosci Rep. 2020;40(1):1-10. 10.1042/BSR20193510.
Google Scholar | Crossref40. Tublin, JM, Adelstein, JM, Del Monte, F, Combs, CK, Wold, LE. Getting to the heart of alzheimer disease. Circ Res. 2019;124(1):142-149. 10.1161/CIRCRESAHA.118.313563.
Google Scholar | Crossref | Medline41. Irwin, M, Tare, M, Singh, A, et al.. A positive feedback loop of hippo- and c-jun-amino-terminal kinase signaling pathways regulates amyloid-beta-mediated neurodegeneration. Front Cell Dev Biol. 2020;8:117. 10.3389/fcell.2020.00117.
Google Scholar | Crossref | Medline42. Bader, JR, Vaughan, KT. Dynein at the kinetochore: timing, interactions and functions. Semin Cell Dev Biol. 2010;21(3):269-275. 10.1016/j.semcdb.2009.12.015.
Google Scholar | Crossref | Medline43. Vallee, RB, Seale, GE, Tsai, JW. Emerging roles for myosin II and cytoplasmic dynein in migrating neurons and growth cones. Trends Cell Biol. 2009;19(7):347-355. 10.1016/j.tcb.2009.03.009.
Google Scholar | Crossref | Medline44. Riera, J, Lazo, PS. The mammalian NudC-like genes: a family with functions other than regulating nuclear distribution. Cell Mol Life Sci. 2009;66(14):2383-2390. 10.1007/s00018-009-0025-3.
Google Scholar | Crossref | Medline45. Schiavo, G, Greensmith, L, Hafezparast, M, Fisher, EMC. Cytoplasmic dynein heavy chain: the servant of many masters. Trends Neurosci. 2013;36(11):641-651. 10.1016/j.tins.2013.08.001.

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