Reassessing Diabetes and APOE Genotype as Potential Interacting Risk Factors for Alzheimer’s Disease

1. Schachter, AS, Davis, KL. Alzheimer’s disease. Dialogues Clin Neurosci. 2000;2(2):91-100.
Google Scholar | Crossref | Medline2. Hebert, LE, Scherr, PA, Bienias, JL, Bennett, DA, Evans, DA. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol. 2003;60(8):1119-1122.
Google Scholar | Crossref | Medline3. Scott, KR, Barrett, AM. Dementia syndromes: evaluation and treatment. Expert Rev Neurother. 2007;7(4):407-422.
Google Scholar | Crossref | Medline4. Perl, DP . Neuropathology of Alzheimer’s disease. Mt Sinai J Med. 2010;77(1):32-42.
Google Scholar | Crossref | Medline5. Corder, EH, Saunders, AM, Strittmatter, WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families. Science. 1993;261:921-923.
Google Scholar | Crossref | Medline | ISI6. Farrer, LA, Cupples, LA, Haines, JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer disease meta analysis consortium. JAMA. 1997;278:1349-1356.
Google Scholar | Crossref | Medline | ISI7. Safieh, M, Korczyn, AD, Michaelson, DM. ApoE4: an emerging therapeutic target for Alzheimer’s disease. BMC Med. 2019;17(64):64.
Google Scholar | Crossref | Medline8. Huang, Y, Mahley, RW. Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer’s diseases. Neurobiol Dis. 2014;72 Pt A:3-12.
Google Scholar | Crossref | Medline | ISI9. Phillips, MC . Apolipoprotein E isoforms and lipoprotein metabolism. IUBMB Life. 2014;66(9):616-623.
Google Scholar | Crossref | Medline10. Martins, CAR, Oulhaj, A, de Jager, CA, Williams, JH. APOE alleles predict the rate of cognitive decline in Alzheimer disease. Neurology. 2005;65(12):1888-1893.
Google Scholar | Crossref | Medline | ISI11. Dik, MG, Jonker, C, Comijs, HC, et al. Memory complaints and APOE-ε4 accelerate cognitive decline in cognitively normal elderly. Neurology. 2001;57(12):2217-2222.
Google Scholar | Crossref | Medline12. Altmann, A, Tian, L, Henderson, VW, Greicius, MD. Alzheimer’s disease neuroimaging initiative investigators. Sex modifies the APOE-related risk of developing Alzheimer disease. Ann Neurol. 2014;75(4):563-573.
Google Scholar | Crossref | Medline | ISI13. Bretsky, P, Guralnik, JM, Launer, L, Albert, M, Seeman, TE. The role of APOE-ε4 in longitudinal cognitive decline. Neurology. 2003;60(7):1077-1081.
Google Scholar | Crossref | Medline14. Blair, CK, Folsom, AR, Knopman, DS, Bray, MS, Mosley, TH, Boerwinkle, E. APOE genotype and cognitive decline in a middle-aged cohort. Neurology. 2005;64(2):268-276.
Google Scholar | Crossref | Medline | ISI15. Cheng, G, Huang, C, Deng, H, Wang, H. Diabetes as a risk factor for dementia and mild cognitive impairment: a meta‐analysis of longitudinal studies. Intern Med J. 2012;42:484-491.
Google Scholar | Crossref | Medline | ISI16. Arvanitakis, Z, Wilson, RS, Bienias, JL, Evans, DA, Bennett, DA. Diabetes mellitus and risk of alzheimer disease and decline in cognitive function. Arch Neurol. 2004;61(5):661-666.
Google Scholar | Crossref | Medline17. de Bruijn, RF, Ikram, MA. Cardiovascular risk factors and future risk of Alzheimer’s disease. BMC Med. 2014;12:130.
Google Scholar | Crossref | Medline | ISI18. Santos, CY, Snyder, PJ, Wu, WC, Zhang, M, Echeverria, A, Alber, J. Pathophysiologic relationship between Alzheimer’s disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis. Alzheimers Dement (Amst). 2017;7:69-87.
Google Scholar | Crossref | Medline19. de la Monte, SM, Wands, JR. Alzheimer’s disease is type 3 diabetes-evidence reviewed. J Diabetes Sci Technol. 2008;2(6):1101-1113.
Google Scholar | SAGE Journals20. Barbagallo, M, Dominguez, LJ. Type 2 diabetes mellitus and Alzheimer’s disease. World J Diabetes. 2014;5(6):889-893.
Google Scholar | Crossref | Medline21. Biessels, GJ, Koffeman, A, Scheltens, P. Diabetes and cognitive impairment. J Neurol. 2006;253:477.
Google Scholar | Crossref | Medline | ISI22. Brands, AMA, Biessels, GJ, de Haan, EHF, Kappelle, LJ, Kessels, RPC. The effects of type 1 diabetes on cognitive performance. Diabetes Care. 2005;28(3):726-735.
Google Scholar | Crossref | Medline | ISI23. Shinohara, M, Tashiro, Y, Suzuki, K, Fukumori, A, Bu, G, Sato, N. Interaction between APOE genotype and diabetes in cognitive decline. Alzheimers Dement (Amst). 2020;12(1):e12006.
Google Scholar | Medline24. Irie, F, Fitzpatrick, AL, Lopez, OL, et al. Enhanced risk for alzheimer disease in persons with type 2 diabetes and apoe ε4: the cardiovascular health study cognition study. Arch Neurol. 2008;65(1):89-93.
Google Scholar | Crossref | Medline25. Peila, R, Rodriguez, BL, Launer, LJ. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies. Diabetes. 2002;51(4):1256-1262.
Google Scholar | Crossref | Medline | ISI26. Martins, I, Hone, E, Foster, J, et al. Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer’s disease and cardiovascular disease. Mol Psychiatr. 2006;11(8):721-736.
Google Scholar | Crossref | Medline | ISI27. Akomolafe, A, Beiser, A, Meigs, J, et al. Diabetes mellitus and risk of developing Alzheimer disease. Arch Neurol. 2006;63(11):1551.
Google Scholar | Crossref | Medline28. Zhang, J, Chen, C, Hua, S, et al. An updated meta-analysis of cohort studies: diabetes and risk of Alzheimer’s disease. Diabetes Res Clin Pract. 2017;124:41-47.
Google Scholar | Crossref | Medline29. Beekly, DL, Ramos, EM, Lee, WW, et al. The National Alzheimer’s coordinating center (NACC) database: the uniform data set. Alzheimer Disease & Associated Disorders. 2007;21(3):249-258.
Google Scholar | Crossref | Medline | ISI30. Besser, L, Kukull, W, Knopman, DS, et al. Version 3 of the national Alzheimer’s coordinating center’s uniform data set. Alzheimer Dis Assoc Disord. 2018;32(4):351-358.
Google Scholar | Crossref | Medline31. Weintraub, S, Besser, L, Dodge, HH, et al. Version 3 of the Alzheimer disease centers’ neuropsychological test battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord. 2018;32(1):10-17.
Google Scholar | Crossref | Medline32. Aldrich, JH, Nelson, FD. Linear Probability, Logit and Probit Model: Quantitative Application in the Social Science. London, UK: Sage pub. Inc; 1984.
Google Scholar | Crossref33. White, I, Royston, P, Wood, A. Multiple imputation using chained equations: issues and guidance for practice. Stat Med. 2010;30(4):377-399.
Google Scholar | Crossref | Medline34. Maccallum, RC, Austin, JT. Applications of structural equation modeling in psychological research. Annu Rev Psychol. 2000;51(1):201-226.
Google Scholar | Crossref | Medline | ISI35. Farrell, AD . Structural equation modeling with longitudinal data: strategies for examining group differences and reciprocal relationships. J Consult Clin Psychol. 1994;62(3):477-487.
Google Scholar | Crossref | Medline | ISI36. Hoyle, RH . Introduction to the special section: structural equation modeling in clinical research. J Consult Clin Psychol. 1994;62(3):427-428.
Google Scholar | Crossref | Medline37. Menke, A, Casagrande, S, Geiss, L, et al. Prevalence of and trends in diabetes among adults in the united states, 1988-2012. JAMA. 2015;314(10):1021-1029.
Google Scholar | Crossref | Medline | ISI38. Xu, G, Liu, B, Sun, Y, et al. Prevalence of diagnosed type 1 and type 2 diabetes among US adults in 2016 and 2017: population based study. BMJ. 2018;362:k1497.
Google Scholar | Crossref | Medline39. Weintraub, S, Carrillo, MC, Farias, ST, et al. Measuring cognition and function in the preclinical stage of Alzheimer’s disease. Alzheimer’s Dement (NY). 2018;4:64-75.
Google Scholar | Crossref | Medline40. Frankenberg, C, Weiner, J, Knebel, M, et al. Verbal fluency in normal aging and cognitive decline: results of a longitudinal study. Comput Speech Lang. 2021;68:195.
Google Scholar | Crossref41. Liu, CC, Kanekiyo, T, Xu, H, Bu, G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol. 2013;9(2):106-118.
Google Scholar | Crossref | Medline | ISI42. Li, X, Song, D, Leng, SX. Link between type 2 diabetes and Alzheimer’s disease: from epidemiology to mechanism and treatment. Clin Interv Aging. 2015;10:549-560.
Google Scholar | Crossref | Medline43. Ferreira, LSS, Fernandes, CS, Vieira, MNN, De Felice, FG. Insulin resistance in Alzheimer’s disease. Front Neurosci. 2018;12:830.
Google Scholar | Crossref | Medline44. Mahley, RW, Weisgraber, KH, Huang, Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer’s disease. Proc Natl Acad Sci U S A. 2006;103(15):5644-5651.
Google Scholar | Crossref | Medline | ISI45. Blázquez, E, Velázquez, E, Hurtado-Carneiro, V, Ruiz-Albusac, JM. Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer’s disease. Front Endocrinol (Lausanne). 2014;5:161.
Google Scholar | Crossref | Medline | ISI46. Looi, J, Sachdev, P. Differentiation of vascular dementia from AD on neuropsychological tests. Neurology. 1999;53:670.
Google Scholar | Crossref | Medline | ISI

留言 (0)

沒有登入
gif