1. Tang, H, Shrager, JB. The signaling network resulting in ventilator-induced diaphragm dysfunction. Am J Respir Cell Mol Biol 2018; 59: 417–427.
Google Scholar | Crossref | Medline2. Vassilakopoulos, T, Petrof, BJ. Ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 2004; 169: 336–341.
Google Scholar | Crossref | Medline | ISI3. Bruells, CS, Marx, G, Rossaint, R. [Ventilator-induced diaphragm dysfunction: clinically relevant problem]. Anaesthesist 2014; 63: 47–53.
Google Scholar | Crossref | Medline4. Yang, HW, Menon, LG, Black, PM, et al SNAI2/Slug promotes growth and invasion in human gliomas. BMC Cancer 2010; 10: 301.
Google Scholar | Crossref | Medline5. Youle, RJ, Narendra, DP. Mechanisms of mitophagy. Nat Rev Mol Cell Biol 2011; 12: 9–14.
Google Scholar | Crossref | Medline | ISI6. Bingol, B, Sheng, M. Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond. Free Radic Biol Med 2016; 100: 210–222.
Google Scholar | Crossref | Medline7. Zhang, YY, Gu, LJ, Huang, J, et al CKD autophagy activation and skeletal muscle atrophy-a preliminary study of mitophagy and inflammation. Eur J Clin Nutr 2019; 73: 950–960.
Google Scholar | Crossref | Medline8. Picard, M, Azuelos, I, Jung, B, et al Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm. J Appl Physiol (1985) 2015; 118: 1161–1171.
Google Scholar | Crossref | Medline9. Lellouche, F, Dionne, S, Simard, S, et al High tidal volumes in mechanically ventilated patients increase organ dysfunction after cardiac surgery. Anesthesiology 2012; 116: 1072–1082.
Google Scholar | Crossref | Medline | ISI10. Azuelos, I, Jung, B, Picard, M, et al Relationship between autophagy and ventilator-induced diaphragmatic dysfunction. Anesthesiology 2015; 122: 1349–1361.
Google Scholar | Crossref | Medline11. Kavazis, AN, Talbert, EE, Smuder, AJ, et al Mechanical ventilation induces diaphragmatic mitochondrial dysfunction and increased oxidant production. Free Radic Biol Med 2009; 46: 842–850.
Google Scholar | Crossref | Medline12. Stassijns, G, Gayan-Ramirez, G, De Leyn, P, et al Systolic ventricular dysfunction causes selective diaphragm atrophy in rats. Am J Respir Crit Care Med 1998; 158: 1963–1967.
Google Scholar | Crossref | Medline13. Martin, M, Li, K, Wright, MC, et al Functional and morphological assessment of diaphragm innervation by phrenic motor neurons. J Vis Exp 2015: e52605.
Google Scholar14. Hudson, MB, Smuder, AJ, Nelson, WB, et al Both high level pressure support ventilation and controlled mechanical ventilation induce diaphragm dysfunction and atrophy. Crit Care Med 2012; 40: 1254–1260.
Google Scholar | Crossref15. Tang, H, Lee, M, Khuong, A, et al Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation. Muscle Nerve 2013; 48: 272–278.
Google Scholar | Crossref | Medline16. Shanely, RA, Zergeroglu, MA, Lennon, SL, et al Mechanical ventilation-induced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activity. Am J Respir Crit Care Med 2002; 166: 1369–1374.
Google Scholar | Crossref | Medline17. Picard, M, Jung, B, Liang, F, et al Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation. Am J Respir Crit Care Med 2012; 186: 1140–1149.
Google Scholar | Crossref | Medline | ISI18. Powers, SK, Hudson, MB, Nelson, WB, et al Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness. Crit Care Med 2011; 39: 1749–1759.
Google Scholar | Crossref | Medline19. Smuder, AJ, Sollanek, KJ, Nelson, WB, et al Crosstalk between autophagy and oxidative stress regulates proteolysis in the diaphragm during mechanical ventilation. Free Radic Biol Med 2018; 115: 179–190.
Google Scholar | Crossref | Medline20. Narendra, D, Tanaka, A, Suen, DF, et al Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008; 183: 795–803.
Google Scholar | Crossref | Medline | ISI21. Lee, H, Yoon, Y. Mitochondrial fission and fusion. Biochem Soc Trans 2016; 44: 1725–1735.
Google Scholar | Crossref | Medline22. Romanello, V, Guadagnin, E, Gomes, L, et al Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 2010; 29: 1774–1785.
Google Scholar | Crossref | Medline23. Zhao, J, Brault, JJ, Schild, A, et al FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 2007; 6: 472–483.
Google Scholar | Crossref | Medline | ISI24. Yin, J, Guo, J, Zhang, Q, et al Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/Parkin pathway. Toxicol In Vitro 2018; 51: 1–10.
Google Scholar | Crossref | Medline25. Lazarou, M, Jin, SM, Kane, LA, et al Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell 2012; 22: 320–333.
Google Scholar | Crossref | Medline26. Kondapalli, C, Kazlauskaite, A, Zhang, N, et al PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2012; 2: 120080.
Google Scholar | Crossref | Medline27. Mouton-Liger, F, Jacoupy, M, Corvol, JC, et al PINK1/Parkin-dependent mitochondrial surveillance: from pleiotropy to Parkinson’s disease. Front Mol Neurosci 2017; 10: 120.
Google Scholar | Crossref | Medline28. Lan, R, Wu, J-T, Wu, T, et al Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway. Brain Res Bull 2018; 142: 63–77.
Google Scholar | Crossref | Medline29. Lecuona, E, Sassoon, CS, Barreiro, E. Lipid overload: trigger or consequence of mitochondrial oxidative stress in ventilator-induced diaphragmatic dysfunction? Am J Respir Crit Care Med 2012; 186: 1074–1076.
Google Scholar | Crossref | Medline30. Schrauwen, P, Schrauwen-Hinderling, V, Hoeks, J, et al Mitochondrial dysfunction and lipotoxicity. Biochim Biophys Acta 2010; 1801: 266–271.
Google Scholar | Crossref | Medline31. Bugger, H, Abel, ED. Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome. Clin Sci (Lond) 2008; 114: 195–210.
Google Scholar | Crossref