Primary leiomyosarcoma of the scalp: a case report and review of the literature

CASE REPORT article

Front. Oncol.

Sec. Neuro-Oncology and Neurosurgical Oncology

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1533114

Provisionally accepted

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Background and Importance: Leiomyosarcoma is a rare and aggressive malignant tumor with a high potential for relapse and metastasis. Correct and timely diagnosis is critical for effective treatment, yet it is often challenging due to the diverse clinical presentations. This case report highlights the significance of early identification and the consequences of delayed diagnosis in scalp leiomyosarcoma.Clinical Presentation: We present the case of a 39-year-old woman with a scalp neoplasm. Initially, the diagnosis was missed, leading to a delay in surgical intervention. The tumor demonstrated a locally aggressive course, infiltrating the skull and dura mater. Upon admission, the scalp tumor was promptly excised. This case provides valuable insights into the varied symptoms and presentations of scalp leiomyosarcoma, which can aid in the recognition of this condition.Conclusion: This report underscores the importance of considering leiomyosarcoma in the differential diagnosis of scalp masses, particularly when the etiology is unclear. Early recognition and intervention are essential to prevent locally invasive growth and potential metastasis, emphasizing the need for a high index of suspicion among healthcare professionals.

Keywords: Leiomyosarcoma, Sarcoma, Scalp, Surgery, case report

Received: 23 Nov 2024; Accepted: 23 Jan 2025.

Copyright: © 2025 . This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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