A 47-year-old woman presented with a two-month history of skin lesions on the lower abdomen and thighs. Physical examination revealed multiple, erythematous, painful nodules with a hard consistency, poor mobility, partial surface erosions, and marginal red infiltrating patches [Figure 1]. A biopsy of the nodule from the patient’s right thigh showed polygonal and cuboidal cells of varying sizes with clear cytoplasm in the dermis [Figure 2]. Immunohistochemistry results were positive for hepatocyte nuclear factor (HNF)-1β, Napsin A, paired box (PAX)-8, and Wilm’s tumour gene (WT)-1, while negative for estrogen receptor (ER). She was undergoing treatment for stage IIIC ovarian clear cell carcinoma and was diagnosed with cutaneous metastases from the carcinoma.

Figure 1: Multiple, erythematous nodules on the lower abdomen and thighs with partial surface erosions and marginal red infiltrating patches.

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Figure 2: Histopathology showing polygonal and cuboidal cells of varying sizes in the dermis with clear cytoplasm (Haematoxylin-eosin; 20x).

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