Degenhardt L, Hall W. Extent of illicit drug use and dependence, and their contribution to the global burden of disease. Lancet. 2012;379(9810):55–70.

Article  PubMed  Google Scholar 

Federal, provincial, and territorial Special Advisory Committee on the Epidemic of Opioid Overdoses. Opioid- and Stimulant-related Harms in Canada. Ottawa:: Public Health Agency of Canada; 2023 [Available from: https://health-infobase.canada.ca/substance-related-harms/opioids-stimulants/.

Ontario Drug Policy Research Network. Ontario Opioid Indicator Tool Toronto, ON: ODPRN; 2023

[updated March 2023. Available from: https://odprn.ca/ontario-opioid-indicator-tool/

Pear VA, Ponicki WR, Gaidus A, Keyes KM, Martins SS, Fink DS, et al. Urban-rural variation in the socioeconomic determinants of opioid overdose. Drug and Alcohol Dependence. 2019;195:66–73.

Article  PubMed  Google Scholar 

McLaughlin MF, Li R, Carrero ND, Bain PA, Chatterjee A. Opioid use disorder treatment for people experiencing homelessness: A scoping review. Drug Alcohol Depend. 2021;224: 108717.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Morin KA, Eibl, JK, Gauthier G, Rush B, Mushquash C, Lightfoot NE, Marsh DC. A cohort study evaluating the association between concurrent mental disorders, mortality, morbidity, and continuous treatment retention for patients in opioid agonist treatment (OAT) across Ontario, Canada using administrative health data [pre-print]. Harm Reduction Journal. 2020.

Bogdanowicz KM, Stewart R, Broadbent M, Hatch SL, Hotopf M, Strang J, et al. Double trouble: Psychiatric comorbidity and opioid addiction-all-cause and cause-specific mortality. Drug Alcohol Depend. 2015;148:85–92.

Article  PubMed  Google Scholar 

Astals M, Domingo-Salvany A, Buenaventura CC, Tato J, Vazquez JM, Martin-Santos R, et al. Impact of substance dependence and dual diagnosis on the quality of life of heroin users seeking treatment. Subst Use Misuse. 2008;43(5):612–32.

Article  PubMed  Google Scholar 

Morin KA, Prevost CR, Eibl JK, Oghene P, Franklyn MT, Moise AR, Marsh DC. A retrospective cohort study evaluating correlates of deep tissue infections among patients enrolled in opioid agonist treatment using administrative data in Ontario, Canada. PLoS One. 2020;15(4):e0232191.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kak V, Chandrasekar PH. Bone and joint infections in injection drug users. Infect Dis Clin North Am. 2002;16(3):681–95.

Article  PubMed  Google Scholar 

Bachmeyer C, Landgraf N, Daumas L. Soft tissue infection caused by Gemella morbillorum in two intravenous drug users. J Am Acad Dermatol. 2005;52(4):704–5.

Article  PubMed  Google Scholar 

Shei A, Rice JB, Kirson NY, Bodnar K, Enloe CJ, Birnbaum HG, et al. Characteristics of high-cost patients diagnosed with opioid abuse. J Manag Care Spec Pharm. 2015;21(10):902–12.

PubMed  Google Scholar 

Hunt KA, Weber EJ, Showstack JA, Colby DC, Callaham ML. Characteristics of frequent users of emergency departments. Ann Emerg Med. 2006;48(1):1–8.

Article  PubMed  Google Scholar 

Richard L, Hwang SW, Forchuk C, Nisenbaum R, Clemens K, Wiens K, et al. Validation study of health administrative data algorithms to identify individuals experiencing homelessness and estimate population prevalence of homelessness in Ontario, Canada. BMJ Open. 2019;9(10): e030221.

Article  PubMed  PubMed Central  Google Scholar 

Pear VA, Ponicki WR, Gaidus A, Keyes KM, Martins SS, Fink DS, et al. Urban-rural variation in the socioeconomic determinants of opioid overdose. Drug Alcohol Depend. 2019;195:66–73.

Article  PubMed  Google Scholar 

Kelleher KJ, Famelia R, Yilmazer T, Mallory A, Ford J, Chavez LJ, et al. Prevention of opioid use disorder: the HOME (housing, opportunities, motivation and engagement) feasibility study. Harm Reduct J. 2021;18(1):112.

Article  PubMed  PubMed Central  Google Scholar 

Atzema CL, Schull MJ, Kurdyak P, Menezes NM, Wilton AS, Vermuelen MJ, et al. Wait times in the emergency department for patients with mental illness. CMAJ. 2012;184(18):E969-76.

Article  PubMed  PubMed Central  Google Scholar 

Hansagi H, Olsson M, Sjoberg S, Tomson Y, Goransson S. Frequent use of the hospital emergency department is indicative of high use of other health care services. Ann Emerg Med. 2001;37(6):561–7.

Article  CAS  PubMed  Google Scholar 

Kurz M, Min JE, Dale LM, Nosyk B. Assessing the determinants of completing OAT induction and long-term retention: A population-based study in British Columbia Canada. J Subst Abuse Treat. 2022;133: 108647.

Article  CAS  PubMed  Google Scholar 

Tahsin F, Morin KA, Vojtesek F, Marsh DC. Measuring treatment attrition at various stages of engagement in Opioid Agonist Treatment in Ontario Canada using a cascade of care framework. BMC Health Serv Res. 2022;22(1):490.

Article  PubMed  PubMed Central  Google Scholar 

Viera A, Bromberg DJ, Whittaker S, Refsland BM, Stanojlović M, Nyhan K, et al. Adherence to and retention in medications for opioid use disorder among adolescents and young adults. Epidemiologic Reviews. 2020;42(1):41–56.

Article  PubMed  PubMed Central  Google Scholar 

Pani PP, Vacca R, Trogu E, Amato L, Davoli M. 2010 Pharmacological treatment for depression during opioid agonist treatment for opioid dependence. Cochrane Database Syst Rev. 2010;9:cd008373.

Google Scholar 

Homayra F, Enns B, Min JE, Kurz M, Bach P, Bruneau J, et al. Comparative analysis of instrumental variables on the assignment of buprenorphine/naloxone or methadone for the treatment of opioid use disorder. Epidemiology. 2024;35(2):218–31.

Article  PubMed  Google Scholar 

Kurz M, Guerra-Alejos BC, Min JE, Barker B, Pauly B, Urbanoski K, et al. Influence of physician networks on the implementation of pharmaceutical alternatives to a toxic drug supply in British Columbia. Implement Sci. 2024;19(1):3.

Article  PubMed  PubMed Central  Google Scholar 

Guerra-Alejos BC, Kurz M, Min JE, Dale LM, Piske M, Bach P, et al. Comparative effectiveness of urine drug screening strategies alongside opioid agonist treatment in British Columbia, Canada: A population-based observational study protocol. BMJ Open. 2023;13(5): e068729.

Article  PubMed  PubMed Central  Google Scholar 

ICES Mission, Vision, Values Toronto, ON: ICES; [Available from: https://www.ices.on.ca/About-ICES/Mission-vision-and-values.

Matheson FI MG, van Ingen T. 2021 J. Ontario marginalization index: user guide. . Toronto, ON:: St. Michael’s Hospital (Unity Health Toronto); 2021.

Alessandro A BF, Bélanger J, Guimond E, and Penney C. 2017 Measuring remoteness and accessibility: A set of indices for Canadian communities. Reports on Special Business Projects. Ottawa ON: Statistics Canada; 2017.

Aird P, Kerr J. Factors affecting rural medicine: An improvement on the rurality index of Ontario. Can J Rural Med. 2007;12(4):245–6.

PubMed  Google Scholar