Meta-analysis of risk factors for postoperative lower extremity deep vein thrombosis in patients with gynecologic malignancies

Front. Surg.

Sec. Obstetrics and Gynecological Surgery

Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1406425

Provisionally accepted

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This study aims to elucidate the risk factors associated with postoperative lower extremity deep vein thrombosis (DVT) in patients afflicted with gynecologic malignancies. A comprehensive search was conducted across CNKI, CQVIP, Wanfang, and PubMed databases for literature published from January 1, 2024, concerning the risk factors for postoperative DVT in patients with gynecologic cancers. Two researchers independently and objectively screened, extracted, and evaluated the pertinent data. Subsequently, the extracted data were subjected to meta-analysis using STATA software. A total of twelve studies fulfilling the inclusion criteria were analyzed, encompassing 2,553 cases. The meta-analysis revealed that significant risk factors for postoperative lower extremity DVT in patients with gynecologic malignancies include age (Odds Ratio [OR]=1.35, 95% Confidence Interval [CI] [1.19, 1.54], P

Keywords: Postoperative Gynecologic Malignancy, Lower extremity deep vein thrombosis, Risk factors, Meta-analysis, prophylaxis, Interventions

Received: 25 Mar 2024; Accepted: 03 Jan 2025.

Copyright: © 2025 . This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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