Multi-cohort analysis identifying core ocular surface microbiome and bacterial alterations in eye diseases

Petrillo F, Pignataro D, Lavano MA, Santella B, Folliero V, Zannella C, et al. Current Evidence on the Ocular Surface Microbiota and Related Diseases. Microorganisms. 2020;8:1033.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aragona P, Baudouin C, Benitez Del Castillo JM, Messmer E, Barabino S, Merayo-Lloves J, et al. The ocular microbiome and microbiota and their effects on ocular surface pathophysiology and disorders. Surv Ophthalmol. 2021;66:907–25.

Article  PubMed  Google Scholar 

Cavuoto KM, Banerjee S, Galor A. Relationship between the microbiome and ocular health. Ocul Surf. 2019;17:384–92.

Article  PubMed  Google Scholar 

St Leger AJ, Desai JV, Drummond RA, Kugadas A, Almaghrabi F, Silver P, et al. An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal gammadelta T Cells. Immunity. 2017;47:148–58e145.

Article  PubMed Central  Google Scholar 

Iwase T, Uehara Y, Shinji H, Tajima A, Seo H, Takada K, et al. Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization. Nature. 2010;465:346–9.

Article  CAS  PubMed  Google Scholar 

Kugadas A, Christiansen SH, Sankaranarayanan S, Surana NK, Gauguet S, Kunz R, et al. Impact of Microbiota on Resistance to Ocular Pseudomonas aeruginosa-Induced Keratitis. PLoS Pathog. 2016;12:e1005855.

Article  PubMed  PubMed Central  Google Scholar 

Momose Y, Hirayama K, Itoh K. Competition for proline between indigenous Escherichia coli and E. coli O157:H7 in gnotobiotic mice associated with infant intestinal microbiota and its contribution to the colonization resistance against E. coli O157:H7. Antonie Van Leeuwenhoek. 2008;94:165–71.

Article  CAS  PubMed  Google Scholar 

Molloy MJ, Bouladoux N, Belkaid Y. Intestinal microbiota: shaping local and systemic immune responses. Semin Immunol. 2012;24:58–66.

Article  CAS  PubMed  Google Scholar 

Graham JE, Moore JE, Jiru X, Moore JE, Goodall EA, Dooley JS, et al. Ocular pathogen or commensal: a PCR-based study of surface bacterial flora in normal and dry eyes. Invest Ophthalmol Vis Sci. 2007;48:5616–23.

Article  PubMed  Google Scholar 

Liborio AM, Nishiwaki-Dantas MC, Mimica LM, Dantas PE, Lima AL. [Conjunctival microbiota in patients with ocular allergy]. Arq Bras Oftalmol. 2005;68:824–7.

Article  PubMed  Google Scholar 

Tuzhikov A, Dong Q, Panchin A, Thanathanee O, Shalabi N, Nelson D, et al. Keratitis-induced changes to the homeostatic microbiome at the human cornea. Investigative Ophthalmol Vis Sci. 2013;54:2891–91.

Google Scholar 

Zhou Y, Holland MJ, Makalo P, Joof H, Roberts CH, Mabey DC, et al. The conjunctival microbiome in health and trachomatous disease: a case control study. Genome Med. 2014;6:99.

Article  PubMed  PubMed Central  Google Scholar 

Martins EN, Alvarenga LS, Hofling-Lima AL, Freitas D, Zorat-Yu MC, Farah ME, et al. Aerobic bacterial conjunctival flora in diabetic patients. Cornea. 2004;23:136–42.

Article  CAS  PubMed  Google Scholar 

Ozkan J, Nielsen S, Diez-Vives C, Coroneo M, Thomas T, Willcox M. Temporal Stability and Composition of the Ocular Surface Microbiome. Sci Rep. 2017;7:9880.

Article  PubMed  PubMed Central  Google Scholar 

Huang Y, Yang B, Li W. Defining the normal core microbiome of conjunctival microbial communities. Clin Microbiol Infect. 2016;22:643.e7–643.e12.

Article  CAS  PubMed  Google Scholar 

Zhang Z, Zou X, Xue W, Zhang P, Wang S, Zou H. Ocular Surface Microbiota in Diabetic Patients With Dry Eye Disease. Invest Ophthalmol Vis Sci. 2021;62:13.

PubMed  PubMed Central  Google Scholar 

Ozkan J, Willcox MD. The Ocular Microbiome: Molecular Characterisation of a Unique and Low Microbial Environment. Curr Eye Res. 2019;44:685–94.

Article  CAS  PubMed  Google Scholar 

Johnson JS, Spakowicz DJ, Hong BY, Petersen LM, Demkowicz P, Chen L, et al. Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis. Nat Commun. 2019;10:5029.

Article  PubMed  PubMed Central  Google Scholar 

Wen X, Miao L, Deng Y, Bible PW, Hu X, Zou Y, et al. The Influence of Age and Sex on Ocular Surface Microbiota in Healthy Adults. Invest Ophthalmol Vis Sci. 2017;58:6030–7.

Article  CAS  PubMed  Google Scholar 

Zhang Y, Liu ZR, Chen H, Dong WJ, Fan YC, Yu H, et al. Comparative study of bacterial status from conjunctival sac of the elder Qiang minority and Han people with dry eye in Sichuan, China. Int J Ophthalmol. 2012;5:343–7.

PubMed  PubMed Central  Google Scholar 

Delbeke H, Younas S, Casteels I, Joossens M. Current knowledge on the human eye microbiome: a systematic review of available amplicon and metagenomic sequencing data. Acta Ophthalmol. 2021;99:16–25.

Article  PubMed  Google Scholar 

Kugadas A, Gadjeva M. Impact of Microbiome on Ocular Health. Ocul Surf. 2016;14:342–9.

Article  PubMed  PubMed Central  Google Scholar 

Baim AD, Movahedan A, Farooq AV, Skondra D. The microbiome and ophthalmic disease. Exp Biol Med (Maywood). 2019;244:419–29.

Article  CAS  PubMed  Google Scholar 

Willcox MD. Characterization of the normal microbiota of the ocular surface. Exp Eye Res. 2013;117:99–105.

Article  CAS  PubMed  Google Scholar 

Chong J, Liu P, Zhou G, Xia J. Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data. Nat Protoc. 2020;15:799–821.

Article  CAS  PubMed  Google Scholar 

Pickering H, Ramadhani AM, Massae P, Mafuru E, Malisa A, Mbuya K, et al. The conjunctival microbiome before and after azithromycin mass drug administration for trachoma control in a cohort of Tanzanian children. Front Public Health. 2022;10:1015714.

Article  PubMed  PubMed Central  Google Scholar 

Ozkan J, Majzoub ME, Coroneo M, Thomas T, Willcox M. Ocular microbiome changes in dry eye disease and meibomian gland dysfunction. Exp Eye Res. 2023;235:109615.

Article  CAS  PubMed  Google Scholar 

An N, Wang C, Dou X, Liu X, Wu J, Cheng Y. Comparison of 16S rDNA Amplicon Sequencing With the Culture Method for Diagnosing Causative Pathogens in Bacterial Corneal Infections. Transl Vis Sci Technol. 2022;11:29.

Article  PubMed  PubMed Central  Google Scholar 

Ren Z, Liu Q, Li W, Wu X, Dong Y, Huang Y. Profiling of Diagnostic Information of and Latent Susceptibility to Bacterial Keratitis From the Perspective of Ocular Bacterial Microbiota. Front Cell Infect Microbiol. 2021;11:645907.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ren Z, Li W, Liu Q, Dong Y, Huang Y. Profiling of the Conjunctival Bacterial Microbiota Reveals the Feasibility of Utilizing a Microbiome-Based Machine Learning Model to Differentially Diagnose Microbial Keratitis and the Core Components of the Conjunctival Bacterial Interaction Network. Front Cell Infect Microbiol. 2022;12:860370.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ueta M, Hosomi K, Park J, Mizuguchi K, Sotozono C, Kinoshita S, et al. Categorization of the Ocular Microbiome in Japanese Stevens-Johnson Syndrome Patients With Severe Ocular Complications. Front Cell Infect Microbiol. 2021;11:741654.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong X, Wang Y, Wang W, Lin P, Huang Y. Composition and Diversity of Bacterial Community on the Ocular Surface of Patients With Meibomian Gland Dysfunction. Invest Ophthalmol Vis Sci. 2019;60:4774–83.

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