Effect of romosozumab on bone mineral density and trabecular bone score in premenopausal women with low bone mass

DíazCuriel M, García JJ, Carrasco JL, Honorato J, Pérez Cano R, Rapado A, ÁlvarezSanz C (2001) Prevalencia de osteoporosis determinada por densitometría en la población femenina española. Med Clin 116(3):86–88. https://doi.org/10.1016/S0025-7753(01)71732-0

Article  Google Scholar 

Pepe J, Body JJ, Hadji P et al (2020) Osteoporosis in premenopausal women: a clinical narrative review by the ECTS and the IOF. J Clin Endocrinol Metab 105(8). https://doi.org/10.1210/clinem/dgaa306

Hosmer WD, Genant HK, Browner WS (2002) Fractures before menopause: a red flag for physicians. Osteoporos Int 13(4):337–341. https://doi.org/10.1007/s001980200035

Article  CAS  PubMed  Google Scholar 

Wu F, Mason B, Horne A, Ames R, Clearwater J, Liu M, Evans MC, Gamble GD, Reid IR (2002) Fractures between the ages of 20 and 50 years increase women’s risk of subsequent fractures. Arch Intern Med 162(1):33–36. https://doi.org/10.1001/archinte.162.1.33

Article  PubMed  Google Scholar 

Bhalla AK (2010) Management of osteoporosis in a pre-menopausal woman. Best Pract Res Clin Rheumatol 24(3):313–327. https://doi.org/10.1016/j.berh.2010.01.006

Article  PubMed  Google Scholar 

Conradie M, de Villiers T (2022) Premenopausal osteoporosis. Climacteric 25(1):73–80. https://doi.org/10.1080/13697137.2021.1926974

Article  CAS  PubMed  Google Scholar 

Cohen A, Stein EM, Recker RR et al (2013) Teriparatide for idiopathic osteoporosis in premenopausal women: a pilot study. J Clin Endocrinol Metab 98(5):1971–1981. https://doi.org/10.1210/jc.2013-1172

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hong N, Rhee Y (2019) Comparison of efficacy of pharmacologic treatments in pregnancy- and lactation-associated osteoporosis. Clin Rev Bone Mineral Metab 17(2):86–93. https://doi.org/10.1007/s12018-019-09262-2

Article  Google Scholar 

Saag KG, Shane E, Boonen S, Marín F, Donley DW, Taylor KA, Dalsky GP, Marcus R (2007) Teriparatide or alendronate in glucocorticoid-induced osteoporosis. N Engl J Med 357(20):2028–2039. https://doi.org/10.1056/NEJMoa071408

Article  CAS  PubMed  Google Scholar 

Thompson PW, Taylor J, Dawson A (2004) The annual incidence and seasonal variation of fractures of the distal radius in men and women over 25 years in Dorset UK. Injury 35(5):462–466. https://doi.org/10.1016/s0020-1383(03)00117-7

Article  PubMed  Google Scholar 

McClung MR, Grauer A, Boonen S et al (2014) Romosozumab in postmenopausal women with low bone mineral density. N Engl J Med 370(5):412–420. https://doi.org/10.1056/NEJMoa1305224

Article  CAS  PubMed  Google Scholar 

Padhi D, Jang G, Stouch B, Fang L, Posvar E (2011) Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 26(1):19–26. https://doi.org/10.1002/jbmr.173

Article  CAS  PubMed  Google Scholar 

Cosman F, Crittenden DB, Adachi JD et al (2016) Romosozumab treatment in postmenopausal women with osteoporosis. N Engl J Med 375(16):1532–1543. https://doi.org/10.1056/NEJMoa1607948

Article  CAS  PubMed  Google Scholar 

Saag KG, Petersen J, Brandi ML, Karaplis AC, Lorentzon M, Thomas T, Maddox J, Fan M, Meisner PD, Grauer A (2017) Romosozumab or alendronate for fracture prevention in women with osteoporosis. N Engl J Med 377(15):1417–1427. https://doi.org/10.1056/NEJMoa1708322

Article  CAS  PubMed  Google Scholar 

Lewiecki EM, Blicharski T, Goemaere S, Lippuner K, Meisner PD, Miller PD, Miyauchi A, Maddox J, Chen L, Horlait S (2018) A phase III randomized placebo-controlled trial to evaluate efficacy and safety of romosozumab in men with osteoporosis. J Clin Endocrinol Metab 103(9):3183–3193. https://doi.org/10.1210/jc.2017-02163

Article  PubMed  Google Scholar 

Mochizuki T, Yano K, Ikari K, Hiroshima R, Okazaki K (2023) Comparison of romosozumab versus denosumab treatment on bone mineral density after 1 year in rheumatoid arthritis patients with severe osteoporosis: a randomized clinical pilot study. Mod Rheumatol 33(3):490–495. https://doi.org/10.1093/mr/roac059

Article  PubMed  Google Scholar 

Uehara M, Nakamura Y, Nakano M, Miyazaki A, Suzuki T, Takahashi J (2021) Efficacy of romosozumab for osteoporosis in a patient with osteogenesis imperfecta: a case report. Modern Rheumatol Case Reports 6(1):128–133. https://doi.org/10.1093/mrcr/rxab018

Article  Google Scholar 

Kim KJ, Hong N, Lee S, Shin S, Rhee Y (2023) Exploratory use of romosozumab for osteoporosis in a patient with Hajdu-Cheney syndrome: a case report. Osteoporos Int 34(5):1005–1009. https://doi.org/10.1007/s00198-023-06668-z

Article  CAS  PubMed  Google Scholar 

Kaneuchi Y, Iwabuchi M, Hakozaki M, Yamada H, Konno S-i (2023) Pregnancy and lactation-associated osteoporosis successfully treated with romosozumab: a case report. Medicina 59(1):19

Article  Google Scholar 

Shuhart CR, Yeap SS, Anderson PA, Jankowski LG, Lewiecki EM, Morse LR, Rosen HN, Weber DR, Zemel BS, Shepherd JA (2019) Executive summary of the 2019 ISCD Position Development Conference on Monitoring Treatment, DXA cross-calibration and least significant change, spinal cord injury, peri-prosthetic and orthopedic bone health, transgender medicine, and pediatrics. J Clin Densitom 22(4):453–471. https://doi.org/10.1016/j.jocd.2019.07.001

Cohen A, Recker RR, Lappe J et al (2012) Premenopausal women with idiopathic low-trauma fractures and/or low bone mineral density. Osteoporos Int 23(1):171–182. https://doi.org/10.1007/s00198-011-1560-y

Article  CAS  PubMed  Google Scholar 

Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC (1998) Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J Clin Invest 102(2):274–282. https://doi.org/10.1172/jci2799

Shi XM, Blair HC, Yang X, McDonald JM, Cao X (2000) Tandem repeat of C/EBP binding sites mediates PPARgamma2 gene transcription in glucocorticoid-induced adipocyte differentiation. J Cell Biochem 76(3):518–527. https://doi.org/10.1002/(sici)1097-4644(20000301)76:3%3c518::aid-jcb18%3e3.0.co;2-m

Article  CAS  PubMed  Google Scholar 

Cárcamo-Orive I, Gaztelumendi A, Delgado J, Tejados N, Dorronsoro A, Fernández-Rueda J, Pennington DJ, Trigueros C (2010) Regulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP-1 crosstalk. J Bone Miner Res 25(10):2115–2125. https://doi.org/10.1002/jbmr.120

Article  CAS  PubMed  Google Scholar 

Mak W, Shao X, Dunstan CR, Seibel MJ, Zhou H (2009) Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells. Calcif Tissue Int 85(6):538–545. https://doi.org/10.1007/s00223-009-9303-1

Article  CAS  PubMed  Google Scholar 

Hofbauer LC, Gori F, Riggs BL, Lacey DL, Dunstan CR, Spelsberg TC, Khosla S (1999) Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 140(10):4382–4389. https://doi.org/10.1210/endo.140.10.7034

Article  CAS  PubMed  Google Scholar 

Kondo T, Kitazawa R, Yamaguchi A, Kitazawa S (2008) Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels. J Cell Biochem 103(1):335–345. https://doi.org/10.1002/jcb.21414

Article  CAS  PubMed  Google Scholar 

Seibel MJ, Cooper MS, Zhou H (2013) Glucocorticoid-induced osteoporosis: mechanisms, management, and future perspectives. Lancet Diabetes Endocrinol 1(1):59–70. https://doi.org/10.1016/s2213-8587(13)70045-7

Article  CAS  PubMed  Google Scholar 

Donovan MA, Dempster D, Zhou H, McMahon DJ, Fleischer J, Shane E (2005) Low bone formation in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 90(6):3331–3336. https://doi.org/10.1210/jc.2004-2042

Article  CAS  PubMed  Google Scholar 

Cohen A, Dempster DW, Recker RR et al (2011) Abnormal bone microarchitecture and evidence of osteoblast dysfunction in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 96(10):3095–3105. https://doi.org/10.1210/jc.2011-1387

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cohen A, Kamanda-Kosseh M, Dempster DW et al (2019) Women with pregnancy and lactation-associated osteoporosis (PLO) have low bone remodeling rates at the tissue level. J Bone Miner Res 34(9):1552–1561. https://doi.org/10.1002/jbmr.3750

Article  CAS 

留言 (0)

沒有登入
gif