In this study, we report on a C-H functionalization of 1,3-dicarbonyl compounds via a photocatalytic nitrene transfer reaction. A wide range of 1,3-dicarbonyl substrates and iodinanes were found compatible with the reaction conditions to directly afford the C-H functionalization products without the need of preformation of nucleophilic enolate equivalents. Additionally, a comprehensive series of synthetic applications and control experiments were conducted, thereby further extending the practical utility of this approach.

You have access to this article

Please wait while we load your content... Something went wrong. Try again?