Bousquet J, Anto JM, Bachert C, Baiardini I, Bosnic-Anticevich S, Walter Canonica G et al (2020) Allergic rhinitis. Nat Reviews Disease Primers.;6(1)

Nur Husna SM, Tan H-TT, Md Shukri N, Mohd Ashari NS, Wong KK (2022) Allergic rhinitis: a clinical and pathophysiological overview. Front Med.;9

Dykewicz MS, Wallace DV, Amrol DJ, Baroody FM, Bernstein JA, Craig TJ et al (2020) Rhinitis 2020: a practice parameter update. J Allergy Clin Immunol 146(4):721–767

Article  CAS  PubMed  Google Scholar 

Zoabi Y, Levi-Schaffer F, Eliashar R (2022) Allergic rhinitis: pathophysiology and treatment focusing on mast cells. Biomedicines.;10(10)

Bjermer L, Westman M, Holmström M, Wickman MC (2019) The complex pathophysiology of allergic rhinitis: scientific rationale for the development of an alternative treatment option. Allergy Asthma Clin Immunol.;15(1)

Abdo-Sultan MK, Abd-El-Lateef RS, Kamel FZ (2019) Efficacy of Omega-3 fatty acids supplementation versus Sublingual Immunotherapy in patients with bronchial asthma. Egypt J Immunol 26(1):79–89

PubMed  Google Scholar 

Werkhäuser N, Pieper-Fürst U, Sahin H, Claas A, Mösges R (2023) Rhinosinusitis Treatment with Cineole: patient-reported quality of Life improvements from a non-interventional, pharmacy-based survey. Medicines 10(6):37

Article  PubMed  PubMed Central  Google Scholar 

Arooj B, Asghar S, Saleem M, Khalid SH, Asif M, Chohan T et al (2023) Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen. Inflammopharmacology 31(4):1849–1862

Article  CAS  PubMed  Google Scholar 

Nakamura T, Yoshida N, Yamanoi Y, Honryo A, Tomita H, Kuwabara H et al (2020) Eucalyptus oil reduces allergic reactions and suppresses mast cell degranulation by downregulating IgE-FcεRI signalling. Sci Rep.;10(1)

Juergens UR, Dethlefsen U, Steinkamp G, Gillissen A, Repges R, Vetter H (2003) Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial. Respir Med 97(3):250–256

Article  CAS  PubMed  Google Scholar 

Miyata J, Arita M (2015) Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases. Allergology Int 64(1):27–34

Article  CAS  Google Scholar 

Ipci K, Oktemer T, Muluk NB, Şahin E, Altıntoprak N, Bafaqeeh SA et al (2016) Alternative products to treat allergic rhinitis and alternative routes for allergy immunotherapy. Am J Rhinol Allergy 30(5):8–10

Article  PubMed  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Syst Reviews.;10(1)

Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I et al (2019) RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ.:l4898

Choi SY, Park K (2016) Effect of Inhalation of Aromatherapy Oil on patients with perennial allergic rhinitis: a Randomized Controlled Trial. Evidence-Based Complement Altern Med 2016:7896081

Article  Google Scholar 

Kehrl W, Sonnemann U, Dethlefsen U (2004) Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial. Laryngoscope 114(4):738–742

Article  PubMed  Google Scholar 

Ojeda P, Piqué N, Alonso A, Delgado J, Feo F, Igea JM et al (2013) A topical microemulsion for the prevention of allergic rhinitis symptoms: results of a randomized, controlled, double-blind, parallel group, multicentre, multinational clinical trial (Nares study). Allergy Asthma Clin Immunol 9(1):32

Article  PubMed  PubMed Central  Google Scholar 

Seol GH, Kim KY (2016) Eucalyptol and its role in Chronic diseases. In: Gupta SC, Prasad S, Aggarwal BB (eds) Drug Discovery from Mother Nature. Springer International Publishing, Cham, pp 389–398

Chapter  Google Scholar 

Smruti P (2021) A review on natural remedies used for the treatment of respiratory disorders. Int J Pharm 8:104–111

CAS  Google Scholar 

Ipci K, Oktemer T, Muluk NB, Şahin E, Altintoprak N, Ali Bafaqeeh S et al (2016) Alternative products to treat allergic Rhinitis and Alternative routes for Allergy Immunotherapy. Am J Rhinol Allergy 30(5suppl):S8–S10

Article  Google Scholar 

Juergens UR (2014) Anti-inflammatory properties of the monoterpene 1.8-cineole: current evidence for co-medication in inflammatory airway diseases. Drug Res (Stuttg) 64(12):638–646

Article  CAS  PubMed  Google Scholar 

Juergens LJ, Worth H, Juergens UR (2020) New perspectives for Mucolytic, anti-inflammatory and adjunctive therapy with 1,8-Cineole in COPD and Asthma: review on the New Therapeutic Approach. Adv Therapy 37(5):1737–1753

Article  CAS  Google Scholar 

Kesharwani V, Gupta S, Kushwaha N, Kesharwani R, Patel DK (2018) A review on therapeutics application of eucalyptus oil. Int J Herb Med 6(6):110–115

Google Scholar 

Roehm CE, Tessema B, Brown SM (2012) The role of Alternative Medicine in Rhinology. Facial Plast Surg Clin North Am 20(1):73–81

Article  PubMed  Google Scholar 

Heimall J, Bielory L (2004) Defining complementary and alternative medicine in allergies and asthma. Clin Rev Allergy Immunol 27(2):93–103

Article  PubMed  Google Scholar 

Niggemann B, Grüber C (2003) Side-effects of complementary and alternative medicine. Allergy 58(8):707–716

Article  CAS  PubMed  Google Scholar