Funding

Open Access funding enabled and organized by Projekt DEAL. This work was supported by the German Center for Infection Research under grant agreement TTU-TB 02.709.

Data availability

The data that support the findings of this study are not openly available due to reasons of sensitivity and are available from the corresponding author upon reasonable request. Data are located in controlled access data storage at the Research Center Borstel, Leibniz Lung Center.

Conflict of interest

Niklas Köhler reports receiving project grants from the Schleswig-Holstein Society for Prevention and Control of Tuberculosis and Pulmonary Diseases for work outside the scope of the submitted work. Christoph Lange reports a grant from the German Center for Infection Research. He holds leadership roles in TBNET and The International Union against TB and Lung Diseases and received honoraria from GSK, Gilead, Insmed, and MedUpdate for speaking engagements, outside the scope of the submitted work. Barbara Kalsdorf received speaker honoraria for lectures from Insmed Germany GMBH, and Astra Zeneca Deutschland, as well as support for attending meetings and/or travel from Astra Zeneca Deutschland, GSK Deutschland, and Boehringer Ingelheim Deutschland, outside the scope of the submitted work. Anika Rauch, Thomas Theo Brehm, Nika Zielinski, Krista Stoycheva, Christina Maier, Laura Böttcher, Inna Friesen, Dagmar Schaub, Maja Reimann and Stefan Schmiedel each report no conflict of interest related to the manuscript.

Author contribution

Anika Rauch: conceptualisation, methodology, validation, formal analysis, investigation, data curation, writing—original draft, visualisation, project administration. Niklas Köhler: conceptualisation, methodology, validation, formal analysis, investigation, data curation, writing—original draft, visualisation, project administration. Thomas Theo Brehm: methodology, formal analysis, investigation, writing—original draft, supervision. Nika Zielinski: methodology, software, formal analysis, investigation, data curation, writing—original draft, visualisation. Krista Stoycheva: methodology, investigation, writing—review and editing, project administration. Christina Maier: conceptualisation, validation, formal analysis, investigation, resources, data curation, writing—original draft. Laura Böttcher: conceptualisation, validation, investigation, resources, data curation, writing—original draft. Inna Friesen: validation, resources, writing—review and editing, supervision. Dagmar Schaub: formal analysis, investigation, data curation, writing—review and editing, project administration. Maja Reimann: conceptualisation, methodology, validation, formal analysis, investigation, data curation, writing—original draft, visualisation, supervision. Stefan Schmiedel: conceptualisation, methodology, writing—review and editing, visualisation, supervision. Christoph Lange: conceptualisation, methodology, investigation, resources, writing—original draft, supervision, project administration, funding acquisition. Barbara Kalsdorf: conceptualisation, methodology, investigation, resources, writing—original draft, supervision, project administration.

Ethics approval

Ethical approval was waived by the local Ethics Committee of University of Lübeck (24-215) in view of the retrospective nature of the study and all the procedures being performed were part of the routine care.