Gestels T, Vandenplas Y. Prenatal and perinatal antibiotic exposure and long-term outcome. Pediatr Gastroenterol Hepatol Nutr. 2023;26:135–45. https://doi.org/10.5223/pghn.2023.26.3.135.

Article  PubMed  PubMed Central  Google Scholar 

Ortqvist AK, Lundholm C, Halfvarson J, et al. Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease: a population-based study. Gut. 2019;68:218–25. https://doi.org/10.1136/gutjnl-2017-314352.

Article  CAS  PubMed  Google Scholar 

Alhasan MM, Cait AM, Heimesaat MM, et al. Antibiotic use during pregnancy increases offspring asthma severity in a dose-dependent manner. Allergy. 2020;75:1979–90. https://doi.org/10.1111/all.14234.

Article  CAS  PubMed  Google Scholar 

Miyoshi J, Bobe AM, Miyoshi S, et al. Peripartum antibiotics promote gut dysbiosis, loss of immune tolerance, and inflammatory bowel disease in genetically prone offspring. Cell Rep. 2017;20:491–504. https://doi.org/10.1016/j.celrep.2017.06.060.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miyoshi J, Lee STM, Kennedy M, et al. Metagenomic alterations in gut microbiota precede and predict onset of colitis in the IL10 gene-deficient murine model. Cell Mol Gastroenterol Hepatol. 2021;11:491–502. https://doi.org/10.1016/j.jcmgh.2020.08.008.

Article  CAS  PubMed  Google Scholar 

Miyoshi J, Miyoshi S, Delmont TO, et al. Early-life microbial restitution reduces colitis risk promoted by antibiotic-induced gut dysbiosis in interleukin 10(-/-) mice. Gastroenterology. 2021;161:940-52 e15. https://doi.org/10.1053/j.gastro.2021.05.054.

Article  CAS  PubMed  Google Scholar 

Schroeder BO, Backhed F. Signals from the gut microbiota to distant organs in physiology and disease. Nat Med. 2016;22:1079–89. https://doi.org/10.1038/nm.4185.

Article  CAS  PubMed  Google Scholar 

Hou K, Wu ZX, Chen XY, et al. Microbiota in health and diseases. Signal Transduct Target Ther. 2022;7:135. https://doi.org/10.1038/s41392-022-00974-4.

Article  PubMed  PubMed Central  Google Scholar 

Goodrich JK, Waters JL, Poole AC, et al. Human genetics shape the gut microbiome. Cell. 2014;159:789–99. https://doi.org/10.1016/j.cell.2014.09.053.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu GD, Chen J, Hoffmann C, et al. Linking long-term dietary patterns with gut microbial enterotypes. Science. 2011;334:105–8. https://doi.org/10.1126/science.1208344.

Article  CAS  PubMed  PubMed Central  Google Scholar 

David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505:559–63. https://doi.org/10.1038/nature12820.

Article  CAS  PubMed  Google Scholar 

Yatsunenko T, Rey FE, Manary MJ, et al. Human gut microbiome viewed across age and geography. Nature. 2012;486:222–7. https://doi.org/10.1038/nature11053.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Buford TW. (Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease. Microbiome. 2017;5:80. https://doi.org/10.1186/s40168-017-0296-0.

Article  PubMed  PubMed Central  Google Scholar 

Afzaal M, Saeed F, Shah YA, et al. Human gut microbiota in health and disease: unveiling the relationship. Front Microbiol. 2022;13: 999001. https://doi.org/10.3389/fmicb.2022.999001.

Article  PubMed  PubMed Central  Google Scholar 

Tamburini S, Shen N, Wu HC, et al. The microbiome in early life: implications for health outcomes. Nat Med. 2016;22:713–22. https://doi.org/10.1038/nm.4142.

Article  CAS  PubMed  Google Scholar 

Underwood MA, Mukhopadhyay S, Lakshminrusimha S, et al. Neonatal intestinal dysbiosis. J Perinatol. 2020;40:1597–608. https://doi.org/10.1038/s41372-020-00829-2.

Article  PubMed  PubMed Central  Google Scholar 

Miyoshi J, Hisamatsu T. The impact of maternal exposure to antibiotics on the development of child gut microbiome. Immunol Med. 2022;45:63–8. https://doi.org/10.1080/25785826.2021.1963189.

Article  CAS  PubMed  Google Scholar 

Backhed F, Roswall J, Peng Y, et al. Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe. 2015;17:690–703. https://doi.org/10.1016/j.chom.2015.04.004.

Article  CAS  PubMed  Google Scholar 

Ferretti P, Pasolli E, Tett A, et al. Mother-to-infant microbial transmission from different body sites shapes the developing infant gut microbiome. Cell Host Microbe. 2018;24:133-45 e5. https://doi.org/10.1016/j.chom.2018.06.005.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martinez I, Maldonado-Gomez MX, Gomes-Neto JC, et al. Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly. Elife. 2018. https://doi.org/10.7554/eLife.36521.

Article  PubMed  PubMed Central  Google Scholar 

Sprockett D, Fukami T, Relman DA. Role of priority effects in the early-life assembly of the gut microbiota. Nat Rev Gastroenterol Hepatol. 2018;15:197–205. https://doi.org/10.1038/nrgastro.2017.173.

Article  PubMed  PubMed Central  Google Scholar 

Broe A, Pottegard A, Lamont RF, et al. Increasing use of antibiotics in pregnancy during the period 2000–2010: prevalence, timing, category, and demographics. BJOG. 2014;121:988–96. https://doi.org/10.1111/1471-0528.12806.

Article  CAS  PubMed  Google Scholar 

de Jonge L, Bos HJ, van Langen IM, et al. Antibiotics prescribed before, during and after pregnancy in the Netherlands: a drug utilization study. Pharmacoepidemiol Drug Saf. 2014;23:60–8. https://doi.org/10.1002/pds.3492.

Article  CAS  PubMed  Google Scholar 

Trinh NTH, Hjorth S, Nordeng HME. Use of interrupted time-series analysis to characterise antibiotic prescription fills across pregnancy: a Norwegian nationwide cohort study. BMJ Open. 2021;11: e050569. https://doi.org/10.1136/bmjopen-2021-050569.

Article  PubMed  PubMed Central  Google Scholar 

Tran A, Zureik M, Sibiude J, et al. Prevalence and associated factors of antibiotic exposure during pregnancy in a large French population-based study during the 2010–19 period. J Antimicrob Chemother. 2023;78:2535–43. https://doi.org/10.1093/jac/dkad266.

Article  CAS  PubMed  Google Scholar 

Okoshi K, Sakurai K, Yamamoto M, et al. Maternal antibiotic exposure and childhood allergies: the Japan environment and children’s Study. J Allergy Clin Immunol Glob. 2023;2: 100137. https://doi.org/10.1016/j.jacig.2023.100137.

Article  PubMed  PubMed Central  Google Scholar 

Nakitanda AO, Kieler H, Odsbu I, et al. In-utero antibiotic exposure and subsequent infections in infancy: a register-based cohort study with sibling analysis. Am J Obstet Gynecol MFM. 2023;5: 100860. https://doi.org/10.1016/j.ajogmf.2023.100860.

Article  CAS  PubMed  Google Scholar 

Martinez de Tejada B. Antibiotic use and misuse during pregnancy and delivery: benefits and risks. Int J Environ Res Public Health. 2014;11:7993–8009. https://doi.org/10.3390/ijerph110807993.

Article  CAS