Stress/Takotsubo cardiomyopathy (TCM) is a transient regional left ventricular (LV) systolic dysfunction, often mimicking acute myocardial infarction with normal coronary arteries. Rarely TCM can mimic hypertrophic cardiomyopathy (HCM). We describe a case where TCM presented with LV hypertrophy (LVH) and left ventricular outflow tract obstruction (LVOTO) which resolved on follow-up.