Front. Med.

Sec. Intensive Care Medicine and Anesthesiology

Volume 11 - 2024 | doi: 10.3389/fmed.2024.1500201

Provisionally accepted

The final, formatted version of the article will be published soon.

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Background: Trauma remains a global health issue being one of the leading causes of death worldwide. Sepsis and infections are common complications contributing to mortality, emphasizing the need to understand factors leading to such complications following trauma. Aim: This study aimed to identify risk factors associated with post-trauma sepsis using data from the National Trauma Data Bank (NTDB). Methods: Using the 2017 National Trauma Data Bank (NTDB), this is a retrospective case-control study that looked at pre-hospital and in-hospital patient data. Trauma patients aged over 15 years presenting to the emergency department (ED) and admitted to a tertiary care center were included. The primary outcome assessed was the development of sepsis post-trauma. Logistic regression analysis was used to identify risk factors, considering patient demographics, injury characteristics, and clinical variables. Results: Among 997,970 trauma patients in the 2017 NTDB, 296,974 were excluded, leaving 700,996 patients for analysis, with 2,297 developing sepsis. Patients who developed sepsis were older than those who did not develop sepsis (mean age 57.57 vs. 53.42 years, p-value

Keywords: Trauma, injury, Sepsis, Risk factors, Mortality

Received: 30 Sep 2024; Accepted: 09 Dec 2024.

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