The Editors-in-Chief are issuing this Editorial Expression of Concern to alert readers that concerns have been raised about some of the data reported in this article. Specifically:

The Figure 2a cIAP1 blot duplicates the Figure S3a Actin blot;

The Figure 2b XIAP blot in CasKi duplicates the Figure 3e Input Myc blot;

The Figure 4b GAPDH blot overlaps with the Figure 4d Myc blot;

In Figure S5e, sgDCAF12#1 and #2 panels overlap.

The authors were able to provide raw data for all impacted figures for review by the Publisher. However, in light of the number of image irregularities present in the published manuscript, readers are advised to interpret the data presented in this article with caution.

Dongyue Jiao, Yingji Chen, Yalan Wang, Huiru Sun, Qing Shi, Liang Zhang, Xiaying Zhao, Yajuan Liu, Huiying He, Zeheng Lv, Pingzhao Zhang, Kun Gao, Yan Huang, Yao Li, and Chenji Wang agree with this Editorial Expression of Concern. Liang Li and Chuan Liu did not respond to correspondence from the Publisher regarding this Editorial Expression of Concern.