Evaluating the impact of cardiac substructure dosimetric parameters on survival in lung cancer patients undergoing postoperative radiotherapy

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229–263

Article  PubMed  Google Scholar 

Chang JY, Mehran RJ, Feng L, Verma V, Liao Z, Welsh JW et al (2021) Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery. Lancet Oncol 22(10):1448–1457. https://doi.org/10.1016/s1470-2045(21)00401-0

Article  PubMed  PubMed Central  Google Scholar 

Antonia SJ, Villegas A, Daniel D, Vicente D, Murakami S, Hui R et al (2017) Durvalumab after chemoradiotherapy in stage III non-small-cell lung cancer. N Engl J Med 377(20):1919–1929. https://doi.org/10.1056/NEJMoa1709937

Article  CAS  PubMed  Google Scholar 

Levy A, Mercier O, Péchoux CL (2022) Indications and parameters around postoperative radiation therapy for lung cancer. J Clin Oncol 40(6):556–566. https://doi.org/10.1200/jco.21.01774

Article  CAS  PubMed  Google Scholar 

Bradley JD, Paulus R, Komaki R, Masters G, Blumenschein G, Schild S et al (2015) Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study. Lancet Oncol 16(2):187–199. https://doi.org/10.1016/S1470-2045(14)71207-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chun SG, Hu C, Choy H, Komaki RU, Timmerman RD, Schild SE et al (2017) Impact of intensity-modulated radiation therapy technique for locally advanced non-small-cell lung cancer: a secondary analysis of the NRG oncology RTOG 0617 randomized clinical trial. J Clin Oncol 35(1):56–62. https://doi.org/10.1200/jco.2016.69.1378

Article  PubMed  Google Scholar 

Zhang TW, Snir J, Boldt RG, Rodrigues GB, Louie AV, Gaede S et al (2019) Is the importance of heart dose overstated in the treatment of non-small cell lung cancer? a systematic review of the literature. Int J Radiat Oncol Biol Phys 104(3):582–589. https://doi.org/10.1016/j.ijrobp.2018.12.044

Article  PubMed  Google Scholar 

Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials. PORT meta-analysis trialists group. Lancet 352(9124):257–263

Dautzenberg B, Arriagada R, Chammard AB, Jarema A, Mezzetti M, Mattson K et al (1999) A controlled study of postoperative radiotherapy for patients with completely resected nonsmall cell lung carcinoma. Groupe d’etude et de traitement des cancers bronchiques. Cancer 86(2):265–273. https://doi.org/10.1002/(sici)1097-0142(19990715)86:2〈265::aid-cncr10〉3.0.co;2‑b

Article  CAS  PubMed  Google Scholar 

Lally BE, Detterbeck FC, Geiger AM, Thomas CR Jr., Machtay M, Miller AA et al (2007) The risk of death from heart disease in patients with nonsmall cell lung cancer who receive postoperative radiotherapy: analysis of the surveillance, epidemiology, and end results database. Cancer 110(4):911–917. https://doi.org/10.1002/cncr.22845

Article  PubMed  Google Scholar 

Douillard JY, Rosell R, De Lena M, Riggi M, Hurteloup P, Mahe MA (2008) Impact of postoperative radiation therapy on survival in patients with complete resection and stage I, II, or IIIA non-small-cell lung cancer treated with adjuvant chemotherapy: the adjuvant Navelbine international Trialist association (ANITA) randomized trial. Int J Radiat Oncol Biol Phys 72(3):695–701. https://doi.org/10.1016/j.ijrobp.2008.01.044

Article  CAS  PubMed  Google Scholar 

Le Pechoux C, Pourel N, Barlesi F, Lerouge D, Antoni D, Lamezec B et al (2022) Postoperative radiotherapy versus no postoperative radiotherapy in patients with completely resected non-small-cell lung cancer and proven mediastinal N2 involvement (lung ART): an open-label, randomised, phase 3 trial. Lancet Oncol 23(1):104–114. https://doi.org/10.1016/s1470-2045(21)00606-9

Article  PubMed  Google Scholar 

Shepherd AF, Yu AF, Iocolano M, Leeman JE, Wild AT, Imber BS et al (2021) Increasing heart dose reduces overall survival in patients undergoing postoperative radiation therapy for NSCLC. JTO Clin Res Rep 2(8):100209. https://doi.org/10.1016/j.jtocrr.2021.100209

Article  PubMed  PubMed Central  Google Scholar 

Lee CC, Chua GWY, Zheng H, Soon YY, Foo LL, Thiagarajan A et al (2019) Are heart doses associated with survival in patients with non-small cell lung cancer who received post-operative thoracic radiotherapy?: a national population-based study. Medicine 98(35):e17020. https://doi.org/10.1097/md.0000000000017020

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martinou M, Gaya A (2013) Cardiac complications after radical radiotherapy. Seminars Oncol 40(2):178–185. https://doi.org/10.1053/j.seminoncol.2013.01.007

Article  Google Scholar 

Wang H, Wei J, Zheng Q, Meng L, Xin Y, Yin X et al (2019) Radiation-induced heart disease: a review of classification, mechanism and prevention. Int J Biol Sci 15(10):2128–2138. https://doi.org/10.7150/ijbs.35460

Article  CAS  PubMed  PubMed Central  Google Scholar 

Banfill K, Giuliani M, Aznar M, Franks K, McWilliam A, Schmitt M et al (2021) Cardiac toxicity of thoracic radiotherapy: existing evidence and future directions. J Thorac Oncol 16(2):216–227. https://doi.org/10.1016/j.jtho.2020.11.002

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng M, Moran JM, Koelling T, Chughtai A, Chan JL, Freedman L et al (2011) Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancer. Int J Radiat Oncol Biol Phys 79(1):10–18. https://doi.org/10.1016/j.ijrobp.2009.10.058

Article  PubMed  Google Scholar 

Duane F, Aznar MC, Bartlett F, Cutter DJ, Darby SC, Jagsi R et al (2017) A cardiac contouring atlas for radiotherapy. Radiother Oncol 122(3):416–422. https://doi.org/10.1016/j.radonc.2017.01.008

Article  PubMed  PubMed Central  Google Scholar 

Wheatley MD, Gore EM, Bar AV, Robinson CG, Bradley JD (2014) Defining a novel cardiac contouring Atlas for NSCLC using cadaveric anatomy. Int J Radiat Oncol Biol Phys 90(1):S658. https://doi.org/10.1016/j.ijrobp.2014.05.1943

Article  Google Scholar 

Milo MLH, Offersen BV, Bechmann T, Diederichsen ACP, Hansen CR, Holtved E et al (2020) Delineation of whole heart and substructures in thoracic radiation therapy: national guidelines and contouring atlas by the danish multidisciplinary cancer groups. Radiother Oncol 150:121–127. https://doi.org/10.1016/j.radonc.2020.06.015

Article  PubMed  Google Scholar 

Yedekci Y, Hurmuz P, Ozyigit G (2023) Effects of reconstruction methods on dose distribution for lung stereotactic body radiotherapy treatment plans. Radiat Environ Biophys 62(1):107–115. https://doi.org/10.1007/s00411-022-01009-w

Article  PubMed  Google Scholar 

Loap P, Servois V, Dhonneur G, Kirov K, Fourquet A, Kirova Y (2021) A radiation therapy contouring Atlas for cardiac conduction node delineation. Pract Radiat Oncol 11(4):e434–e437. https://doi.org/10.1016/j.prro.2021.02.002

Article  PubMed  Google Scholar 

Ma J‑T, Sun L, Sun X, Xiong Z‑C, Liu Y, Zhang S‑L et al (2017) Is pulmonary artery a dose-limiting organ at risk in non-small cell lung cancer patients treated with definitive radiotherapy? Radiat Oncol 12:1–10

Article  Google Scholar 

McWilliam A, Kennedy J, Hodgson C, Vasquez Osorio E, Faivre-Finn C, van Herk M (2017) Radiation dose to heart base linked with poorer survival in lung cancer patients. Eur J Cancer 85:106–113. https://doi.org/10.1016/j.ejca.2017.07.053

Article  PubMed  Google Scholar 

Vivekanandan S, Landau DB, Counsell N, Warren DR, Khwanda A, Rosen SD et al (2017) The impact of cardiac radiation dosimetry on survival after radiation therapy for non-small cell lung cancer. Int J Radiat Oncol Biol Phys 99(1):51–60. https://doi.org/10.1016/j.ijrobp.2017.04.026

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wong OY, Yau V, Kang J, Glick D, Lindsay P, Le LW et al (2018) Survival impact of cardiac dose following lung Stereotactic body radiotherapy. Clin Lung Cancer 19(2):e241–e246. https://doi.org/10.1016/j.cllc.2017.08.002

Article  PubMed  Google Scholar 

McWilliam A, Abravan A, Banfill K, Faivre-Finn C, van Herk M (2023) Demystifying the results of RTOG 0617: identification of dose sensitive cardiac subregions associated with overall survival. J Thorac Oncol 18(5):599–607. https://doi.org/10.1016/j.jtho.2023.01.085

Article  CAS  PubMed  Google Scholar 

Ma Z, Yang X, Hui Z (2023) Association of heart base dose with overall survival in patients with NSCLC undergoing postoperative radiotherapy. J Thorac Oncol 18(6):e62–e64. https://doi.org/10.1016/j.jtho.2023.

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