Jang S, Lee K, Ju JH. Recent updates of diagnosis, pathophysiology, and treatment on osteoarthritis of the knee. Int J Mol Sci. 2021;22(5):2619.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Goldring MB, Goldring SR. Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis. Ann N Y Acad Sci. 2010;1192:230–7.

Article  PubMed  CAS  Google Scholar 

Rosemann T, Laux G, Kuehlein T. Osteoarthritis and functional disability: results of a cross sectional study among primary care patients in Germany. BMC Musculoskelet Disord. 2007;8:79.

Article  PubMed  PubMed Central  Google Scholar 

Ghouri A, Conaghan PG. Prospects for therapies in osteoarthritis. Calcif Tissue Int. 2021;109(3):339–50.

Article  PubMed  CAS  Google Scholar 

Tai FWD, McAlindon ME. Non-steroidal anti-inflammatory drugs and the gastrointestinal tract. Clin Med (Lond). 2021;21(2):131–4.

Article  PubMed  Google Scholar 

Rodriguez-Merchan EC. The current role of disease-modifying osteoarthritis drugs. Arch Bone Jt Surg. 2023;11(1):11–22.

PubMed  PubMed Central  Google Scholar 

Lagier JC, et al. Current and past strategies for bacterial culture in clinical microbiology. Clin Microbiol Rev. 2015;28(1):208–36.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Liu S, et al. “Cross-talk” between gut microbiome dysbiosis and osteoarthritis progression: a systematic review. Front Immunol. 2023;14:1150572.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Jeyaraman M, et al. The gut-joint axis in osteoarthritis. Cureus. 2023;15(11):e48951.

PubMed  PubMed Central  Google Scholar 

Huang Z, Kraus VB. Does lipopolysaccharide-mediated inflammation have a role in OA? Nat Rev Rheumatol. 2016;12(2):123–9.

Article  PubMed  CAS  Google Scholar 

Liu Y, et al. Gut microbiota and obesity-associated osteoarthritis. Osteoarthritis Cartilage. 2019;27(9):1257–65.

Article  PubMed  CAS  Google Scholar 

Boulange CL, et al. Impact of the gut microbiota on inflammation, obesity, and metabolic disease. Genome Med. 2016;8(1):42.

Article  PubMed  PubMed Central  Google Scholar 

Karim A, et al. Metformin effects on plasma zonulin levels correlate with enhanced physical performance in osteoarthritis patients with diabetes. Inflammopharmacology. 2024;32(5):3195–203.

Article  PubMed  CAS  Google Scholar 

Kechagia M, et al. Health benefits of probiotics: a review. ISRN Nutr. 2013;2013:481651.

Article  PubMed  PubMed Central  Google Scholar 

Bodke H, Jogdand S. Role of probiotics in human health. Cureus. 2022;14(11):e31313.

PubMed  PubMed Central  Google Scholar 

Karim A, et al. A multistrain probiotic reduces sarcopenia by modulating Wnt signaling biomarkers in patients with chronic heart failure. J Cardiol. 2022;80(5):449–55.

Article  PubMed  Google Scholar 

Qaisar R, et al. Probiotics supplements improve the sarcopenia-related quality of life in older adults with age-related muscle decline. Calcif Tissue Int. 2024;114(6):583–91.

Article  PubMed  CAS  Google Scholar 

Karim A, et al. A multistrain probiotic improves handgrip strength and functional capacity in patients with COPD: a randomized controlled trial. Arch Gerontol Geriatr. 2022;102:104721.

Article  PubMed  CAS  Google Scholar 

Rahman SO, Bariguian F, Mobasheri A. The potential role of probiotics in the management of osteoarthritis pain: current status and future prospects. Curr Rheumatol Rep. 2023;25(12):307–26.

Article  PubMed  PubMed Central  Google Scholar 

Hao X, et al. The gut microbiota in osteoarthritis: where do we stand and what can we do? Arthritis Res Ther. 2021;23(1):42.

Article  PubMed  PubMed Central  Google Scholar 

Chisari E, et al. The relation between the gut microbiome and osteoarthritis: a systematic review of literature. PLoS ONE. 2021;16(12):e0261353.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Marchese L, et al. The complex interplay between the gut microbiome and osteoarthritis: a systematic review on potential correlations and therapeutic approaches. Int J Mol Sci. 2023;25(1):143.

Article  PubMed  PubMed Central  Google Scholar 

Huang Z, et al. Faecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice. Ann Rheum Dis. 2020;79(5):646–56.

Article  PubMed  CAS  Google Scholar 

Guss JD, et al. The effects of metabolic syndrome, obesity, and the gut microbiome on load-induced osteoarthritis. Osteoarthr Cartil. 2019;27(1):129–39.

Article  CAS  Google Scholar 

Kopczynska J, Kowalczyk M. The potential of short-chain fatty acid epigenetic regulation in chronic low-grade inflammation and obesity. Front Immunol. 2024;15:1380476.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Edwards CJ. Commensal gut bacteria and the etiopathogenesis of rheumatoid arthritis. J Rheumatol. 2008;35(8):1477–14797.

PubMed  Google Scholar 

Vaahtovuo J, et al. Fecal microbiota in early rheumatoid arthritis. J Rheumatol. 2008;35(8):1500–5.

PubMed  CAS  Google Scholar 

Asquith M, et al. The role of the gut and microbes in the pathogenesis of spondyloarthritis. Best Pract Res Clin Rheumatol. 2014;28(5):687–702.

Article  PubMed  PubMed Central  Google Scholar 

Arora V, et al. Gut-microbiota modulation: the impact of thegut-microbiotaon osteoarthritis. Gene. 2021;785:145619.

Article  PubMed  CAS  Google Scholar 

Liu L, et al. The effects and significance of gut microbiota and its metabolites on the regulation of osteoarthritis: close coordination of gut-bone axis. Front Nutr. 2022;9:1012087.

Article  PubMed  PubMed Central  Google Scholar 

Sonnenburg ED, Sonnenburg JL. The ancestral and industrialized gut microbiota and implications for human health. Nat Rev Microbiol. 2019;17(6):383–90.

Article  PubMed  CAS  Google Scholar 

Wallace IJ, et al. Knee osteoarthritis risk in non-industrial societies undergoing an energy balance transition: evidence from the indigenous Tarahumara of Mexico. Ann Rheum Dis. 2019;78(12):1693–8.

Article  PubMed  Google Scholar 

Maciel-Fiuza MF, et al. Role of gut microbiota in infectious and inflammatory diseases. Front Microbiol. 2023;14:1098386.

Article  PubMed  PubMed Central  Google Scholar 

Chow YY, Chin KY. The role of inflammation in the pathogenesis of osteoarthritis. Mediators Inflamm. 2020;2020:8293921.