Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 74(3):229–263. https://doi.org/10.3322/caac.21834

Article  PubMed  Google Scholar 

Paschke S, Jafarov S, Staib L, Kreuser ED, Maulbecker-Armstrong C, Roitman M, Holm T, Harris CC, Link KH, Kornmann M (2018) Are colon and rectal cancer two different tumor entities? a proposal to abandon the term colorectal cancer. Int J Mol Sci 19:2577

Article  PubMed  PubMed Central  Google Scholar 

Alickikus ZA, Kuru A, Aydin B, Akcay D, Gorken IB (2020) The importance of mesorectum motion in determining PTV margins in rectal cancer patients treated with neoadjuvant radiotherapy. J Radiat Res 61(2):335–342

Article  PubMed  Google Scholar 

de Jong R, Visser J, van Wieringen N, Wiersma J, Geijsen D, Bel A (2021) Feasibility of conebeam CT-based online adaptive radiotherapy for neoadjuvant treatment of rectal cancer. Radiat Oncol 16:136

Article  PubMed  PubMed Central  Google Scholar 

Yamashita H, Takenaka R, Sakumi A, Haga A, Otomo K, Nakagawa K (2015) Analysis of motion of the rectum during preoperative intensity modulated radiation therapy for rectal cancer using cone-beam computed tomography. Radiat Oncol 10:2

Article  PubMed  PubMed Central  Google Scholar 

Gregoire V, Guckenberger M, Haustermans K, Lagendijk IJ, Menard C, Potter R, Slotman BJ, Tanderup K, Thorwarth D, Van Herk M, Zips D (2020) Image guidance in radiation therapy for better cure of cancer. Molecular Oncol 14(7):1470–1491

Article  Google Scholar 

Goyal S, Kataria T (2014) Image guidance in radiation therapy: techniques and applications hindawi publishing corporation. Radiol Res Practice. https://doi.org/10.1155/2014/705604

Article  Google Scholar 

Bonomo P, Lo Russo M, Nachbar M, Boeke S, Gatidis S, Zips D, Thorwarth D, Gani C (2021) 1.5 T MR-linac planning study to compare two different strategies of rectal boost irradiation. Clin Transl Radiat Oncology 26:86–91

Article  CAS  Google Scholar 

Boldrini L, Placidi E, Dinapoli N, Azario L, Cellini F, Massaccesi M, Chiesa S, Gambacorta M, Mattiucci G, Piccari D, Teodoli S, De Spirito M, Valentini V (2018) Hybrid Tri-Co-60 MRI radiotherapy for locally advanced rectal cancer: an in silico evaluation. Tech Inno Patient Support Radiation Oncology 6:5–10

Article  Google Scholar 

Srinivasan K, Mohammadi M, Shepherd J (2014) Applications of linac-mounted kilovoltage cone-beam computed tomography in modern radiation therapy. Pol J Radiol 79:181–193

Article  PubMed  PubMed Central  Google Scholar 

Sargison GC, Kundapur V, Park-Somers E, Andreas J, Vachhrajani H, Sidhu NP (2013) Planning target volume margin evaluation and critical structure sparing for rectal cancer patients treated prone on a bellyboard. Clin Oncol 25:17–22

Article  Google Scholar 

Yang Y, Feng L, Wang Y, Ge R, Gong H, Xie C, Wang J, Chen J, Lan Y, Ma L (2015) A dosimetric analysis of preoperative intensity-modulated and image-guided radiation therapy with and without simultaneous integrated boost for locally advanced rectal cancer. Technol Cancer Res Treat 14(5):557–563

Article  CAS  PubMed  Google Scholar 

Lutkenhaus LJ, De Jong R, Geijsen ED, Visser J, Van Wieringen N, Bel A (2016) Potential dosimetric benefit of an adaptive plan selection strategy for short-course radiotherapy in rectal cancer patients. Radiother Oncol 119(3):525–530

Article  PubMed  Google Scholar 

De Jong R, Lutkenhaus L, Van Wieringen N, Visser J, Wiersma J, Crama K, Geijsen D, Bel A (2016) Plan selection strategy for rectum cancer 101 patients: an interobserver study to assess clinical feasibility. Radiother Oncol 120(2):207–211

Article  PubMed  Google Scholar 

Kim A, Karotki A, Presutti J, Gonzales G, Wong S, Chu W (2017) The effect of prone and supine treatment positions for the pre-operative treatment of rectal cancer on organ-at-risk sparing and setup reproducibility using volumetric modulated arc therapy. Radiat Oncol 12:180

Article  PubMed  PubMed Central  Google Scholar 

Van Beek S, Betgen A, Buijs M, Stam J, Hartgring L, Van Triest B, Remeijer P (2018) Pre-clinical experience of an adaptive plan library strategy in radiotherapy of rectal cancer: an inter-observer study. Phys Imag Radiat Oncol 6:89–93

Article  Google Scholar 

Bansal S, Bhattacharyya M, Kalita AK, Singh MN, Sunku R, Medhi PP, Bora G (2019) Determination of optimal clinical target volume to planning target volume margins for conformal radiotherapy planning using image guidance system in rectal cancer in prone position. J Appl Clin Med Phys 44(1):65–67

Google Scholar 

De Jong R, Visser J, Crama KF, Van Wieringen N, Wiersma J, Geijsen ED, Bel A (2020) Dosimetric benefit of an adaptive treatment by means of plan selection for rectal cancer patients in both short and long course radiation therapy. Radiat Oncol 15(1):13

Article  PubMed  PubMed Central  Google Scholar 

De Jong R, Crama KF, Visser J, Van Wieringen N, Wiersma J, Geijsen ED, Bel A (2020) Online adaptive radiotherapy compared to plan selection for rectal cancer: quantifying the benefit. Radiat Oncol 15(1):162

Article  PubMed  PubMed Central  Google Scholar 

Rosa C, Caravatta L, Di Tommas M, Fasciolo D, Gasparini L, Di Guglielmo FC, Augurio A, Vinciguerra A, Vecchi C, Genovesi D (2021) Cone-beam computed tomography for organ motion evaluation in locally advanced rectal cancer patients. Radiol Med 126(1):147–154

Article  PubMed  Google Scholar 

Cox MC, Braam PM, Rütten H, Van Leeuwen R, Wendling M (2021) Mesorectal shape variation in rectal cancer radiotherapy in prone position using a belly board. Phys Imag Radiat Oncol 19:120–125

Article  Google Scholar 

Zhao J, Chen Z, Wang J, Xia F, Peng J, Hu Y, Hu W, Zhang Z (2021) MV CBCT-based synthetic CT generation using a deep learning method for rectal cancer adaptive radiotherapy. Front Oncol 11:655325

Article  PubMed  PubMed Central  Google Scholar 

Seah V, Dundas K, Hudson F, Surjan Y, Bartlett R, Ko R, Smith S, Arumugam S, Johnston M, Wong K, Lee M (2022) Correcting rotational error in rectal cancer radiation therapy: can planning target volume margins be safely reduced. J Med Radiat Sci 69:473–483

Article  PubMed  PubMed Central  Google Scholar 

Nugent K, O’Neill B, Brennan V, Higgins M, Skourou C (2022) Quantification of organ motion in male and female patients undergoing long-course radiation therapy for rectal cancer in the supine position. Adv in Radiat Oncol 8(1):101109

Article  Google Scholar 

Ergen SA, Demir E, Can G, Karacam S, Barlas C, Oksuz DC (2023) Evaluation of interfractional organ motion during neoadjuvant radiotherapy for rectal cancer patients. Bratisl Med J. https://doi.org/10.4149/BLL_2023_043

Article  Google Scholar 

Zhang Z, Yu S, Peng F, Tan Z, Zhang L, Li D, Yang P, Peng Z, Li X, Fang C, Wang Y, Liu Y (2023) Advantages and robustness of partial VMAT with prone position for neoadjuvant rectal cancer evaluated by CBCT-based offline adaptive radiotherapy. Radiat Oncol 18:102

Article  PubMed  PubMed Central  Google Scholar 

Moldovan N, Moor J, Rivest R, Ahmed S, Liu J, Bashir M, Lambert P, Guest M, Nashed M (2023) Evaluation of the ITV-margin and variables affecting bladder and mesorectal deformation during long course neoadjuvant radiotherapy for rectal cancer. Med Dosim 47(3):236–241

Article  Google Scholar 

Feng X, Tang B, Yao X, Liu M, Liao X, Yuan K, Peng Q, Orlandini L (2023) Effectiveness of bladder filling control during online MR-guided adaptive radiotherapy for rectal cancer. Radiat Oncol 18:136

Article  PubMed  PubMed Central  Google Scholar 

Eijkelenkamp H, Boekhoff M, Verweij M, Peters F, Meijer G, Intven M (2021) Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac. Radiother Oncol 162:150–155

Article  PubMed  Google Scholar