Foucar K. Acute lymphoblastic leukemia. In: Foucar K, editor. Bone marrow pathology. 2nd ed. Chicago: ASCP Press; 2001. p. 484–514.

Google Scholar 

Invernizzi R, Rosanda C, Basso G, Conter V, di Cataldo A, Fenu S, Forni M, Frappampina V, Granchi D, Locatelli F, et al. Granular acute lymphoblastic leukemia in children. “Aieop Cooperative Group for Cytology of Acute Leukemias.” Haematologica. 1992;77(1):30–4.

CAS  PubMed  Google Scholar 

Cap J, Babusikova O, Kaiserova E, Panzer-Grünmayer R. Granular acute lymphoblastic leukemia in a 15-year-old boy. Med Oncol. 2000;17(2):144–6. https://doi.org/10.1007/BF02796210.

Article  CAS  PubMed  Google Scholar 

Cantù-Rajnoldi A, Invernizzi R, Biondi A, Banfi P, Zoia A, De Fazio P, Polli N. Biological and clinical features of acute lymphoblastic leukaemia with cytoplasmic granules or inclusions: description of eight cases. Br J Haematol. 1989;73(3):309–14. https://doi.org/10.1111/j.1365-2141.1989.tb07745.x.

Article  PubMed  Google Scholar 

Cerezo L, Shuster JJ, Pullen DJ, Brock B, Borowitz MJ, Falletta JM, Crist WM, Head DR. Laboratory correlates and prognostic significance of granular acute lymphoblastic leukemia in children: a Pediatric Oncology Group study. Am J Clin Pathol. 1991;95(4):526–31. https://doi.org/10.1093/ajcp/95.4.526.

Article  CAS  PubMed  Google Scholar 

Roh J, Cho Y, Han B, Lee YK. The first case of adult granular acute lymphoblastic leukemia with DNMT3A mutation and monosomy 7. Ann Clin Lab Sci. 2022;52(5):846–9.

CAS  PubMed  Google Scholar 

Charlton J, Pritchard-Jones K. WT1 mutation in childhood cancer. Methods Mol Biol. 2016;1467:1–14. https://doi.org/10.1007/978-1-4939-4023-3_1.

Article  PubMed  Google Scholar 

Marjanovic I, Karan-Djurasevic T, Ugrin M, Virijevic M, Vidovic A, Tomin D, Suvajdzic Vukovic N, Pavlovic S, Tosic N. Use of Wilms tumor 1 gene expression as a reliable marker for prognosis and minimal residual disease monitoring in acute myeloid leukemia with normal karyotype patients. Clin Lymphoma Myeloma Leuk. 2017;17(5):312–9. https://doi.org/10.1016/j.clml.2016.12.006. (Epub 2017 Jan 11).

Article  PubMed  Google Scholar 

Hidaka D, Onozawa M, Hashiguchi J, Miyashita N, Kasahara K, Fujisawa S, Hayase E, Okada K, Shiratori S, Goto H, Sugita J, Nakagawa M, Hashimoto D, Kahata K, Endo T, Yamamoto S, Tsutsumi Y, Haseyama Y, Nagashima T, Mori A, Ota S, Sakai H, Ishihara T, Imai K, Miyagishima T, Kakinoki Y, Kurosawa M, Kobayashi H, Iwasaki H, Shimizu C, Kondo T, Teshima T. Wilms tumor 1 expression at diagnosis correlates with genetic abnormalities and polymorphism but is not independently prognostic in acute myelogenous leukemia: a Hokkaido leukemia net study. Clin Lymphoma Myeloma Leuk. 2018;18(11):e469–79. https://doi.org/10.1016/j.clml.2018.07.291. (Epub 2018 Jul 17).

Article  PubMed  Google Scholar 

Wang S, Wang C, Li T, Wang W, Hao Q, Xie X, Wan D, Jiang Z, Liu Y. WT1 overexpression predicted good outcomes in adult B-cell acute lymphoblastic leukemia patients receiving chemotherapy. Hematology. 2020;25(1):118–24. https://doi.org/10.1080/16078454.2020.1735670.

Article  PubMed  Google Scholar 

Niktoreh N, Weber L, Walter C, Karimifard M, Hoffmeister LM, Breiter H, Thivakaran A, Soldierer M, Drexler HG, Schaal H, Sendker S, Reinhardt D, Schneider M, Hanenberg H. Understanding WT1 alterations and expression profiles in hematological malignancies. Cancers. 2023;15(13):3491. https://doi.org/10.3390/cancers15133491.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sadek HA, El-Metnawey WH, Shaheen IA, Korshied MM, Mohamed AS. Quantitative assessment of Wilms tumor 1 (WT1) gene transcripts in Egyptian acute lymphoblastic leukemia patients. J Investig Med. 2011;59(8):1258–62. https://doi.org/10.2130/JIM.0b013e31822a24f7.

Article  CAS  PubMed  Google Scholar 

Niegemann E, Wehner S, Kornhuber B, Schwabe D, Ebener U. WT1 gene expression in childhood leukemias. Acta Haematol. 1999;102(2):72–6. https://doi.org/10.1159/000040973.

Article  CAS  PubMed  Google Scholar 

Ozgen U, Anak S, Ozbek U, Sarper N, Eryilmaz E, Ağaoğlu L, Devecioğlu O, Yalman N, Gedikoğlu G. WT1 gene expression in childhood acute leukemias. Acta Haematol. 2000;103(4):229–30. https://doi.org/10.1159/000041057.

Article  CAS  PubMed  Google Scholar 

Chen JS, Hsiao CC, Sheen JM, Cheng CN. Comparison of minimal residual disease (MRD) estimated by flow cytometry and by real-time quantitative PCR of Wilms tumor gene 1 (WT1) transcript expression in children with acute lymphoblastic leukemia. Leuk Res. 2007;31(10):1351–7. https://doi.org/10.1016/j.leukres.2007.03.006. (Epub 2007 Apr 18).

Article  CAS  PubMed  Google Scholar 

Tosello V, Mansour MR, Barnes K, Paganin M, Sulis ML, Jenkinson S, Allen CG, Gale RE, Linch DC, Palomero T, Real P, Murty V, Yao X, Richards SM, Goldstone A, Rowe J, Basso G, Wiernik PH, Paietta E, Pieters R, Horstmann M, Meijerink JPP, Ferrando AA. WT1 mutations in T-ALL. Blood. 2009;114(5):1038–45. https://doi.org/10.1182/blood-2008-12-192039.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wiemels JL, Zhang Y, Chang J, Zheng S, Metayer C, Zhang L, Smith MT, Ma X, Selvin S, Buffler PA, Wiencke JK. RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia. Leukemia. 2005;19(3):415–9. https://doi.org/10.1038/sj.leu.2403641.

Article  CAS  PubMed  Google Scholar 

Yao YL, Wang XG, Zhao XL, Li SQ, Zhou YJ, Xu YZ. Detection of RAS gene mutation and its clinical significance in children with acute lymphoblastic leukemia. Zhongguo Dang Dai Er Ke Za Zhi. 2022;24(3):309–13. https://doi.org/10.7499/j.issn.1008-8830.2109141.

Article  PubMed  Google Scholar 

Perentesis JP, Bhatia S, Boyle E, Shao Y, Shu XO, Steinbuch M, Sather HN, Gaynon P, Kiffmeyer W, Envall-Fox J, Robison LL. RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia. Leukemia. 2004;18(4):685–92. https://doi.org/10.1038/sj.leu.2403272.

Article  CAS  PubMed  Google Scholar 

Wiemels JL, Kang M, Chang JS, Zheng L, Kouyoumji C, Zhang L, Smith MT, Scelo G, Metayer C, Buffler P, Wiencke JK. Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia. Blood Cells Mol Dis. 2010;45(3):186–91. https://doi.org/10.1016/j.bcmd.2010.07.007. (Epub 2010 Aug 5).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford S, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui C-H, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012;481(7380):157–63. https://doi.org/10.1038/nature10725.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Case M, Matheson E, Minto L, Hassan R, Harrison CJ, Bown N, Bailey S, Vormoor J, Hall AG, Irving JA. Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia. Cancer Res. 2008;68(16):6803–9. https://doi.org/10.1158/0008-5472.CAN-08-0101.

Article  CAS  PubMed  Google Scholar 

Li B, Chng WJ. EZH2 abnormalities in lymphoid malignancies: underlying mechanisms and therapeutic implications. J Hematol Oncol. 2019;12(1):118. https://doi.org/10.1186/s13045-019-0814-6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meyer C, Larghero P, Almeida Lopes B, et al. The KMT2A recombinome of acute leukemias in 2023. Leukemia. 2023;37(5):988–1005. https://doi.org/10.1038/s41375-023-01877-1. (Epub 2023 Apr 5).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kundu A, Kowarz E, Marschalek R. The role of reciprocal fusions in MLL-r acute leukemia: studying the chromosomal translocation t(6;11). Oncogene. 2021;40(40):5902–12. https://doi.org/10.1038/s41388-021-01983-3. (Epub 2021 Aug 5).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu YL, Zhang Y, Zhu P, Yang Y, Du JW, Liu J. Role of molecular screening for common fusion genes in the diagnosis and classification of leukemia. Beijing Da Xue Xue Bao Yi Xue Ban. 2005;37(3):236–9 (Chinese).

CAS  PubMed  Google Scholar 

Sin CF, Man P