Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014;513(7517):202–9.
Knight WR, Allum WH. Gastric tumours. Medicine. 2019;47(5):309–13.
Shimizu T, Marusawa H, Watanabe N, Chiba T. Molecular pathogenesis of helicobacter pylori-related gastric cancer. Gastroenterol Clin North Am. 2015;44(3):625–38.
Deng H, Kan A, Lyu N, He M, Huang X, Qiao S, et al. Tumor-derived lactate inhibit the efficacy of lenvatinib through regulating PD-L1 expression on neutrophil in hepatocellular carcinoma. J Immunother Cancer. 2021. https://doi.org/10.1136/jitc-2020-002305.
Article PubMed PubMed Central Google Scholar
Li S, Gao J, Xu Q, Zhang X, Huang M, Dai X, et al. A signature-based classification of gastric cancer that stratifies tumor immunity and predicts responses to PD-1 inhibitors. Front Immunol. 2021;12: 693314.
Article CAS PubMed PubMed Central Google Scholar
Seeneevassen L, Bessede E, Megraud F, Lehours P, Dubus P, Varon C. Gastric cancer: advances in carcinogenesis research and new therapeutic strategies. Int J Mol Sci. 2021. https://doi.org/10.3390/ijms22073418.
Article PubMed PubMed Central Google Scholar
Cisło M, Filip AA, Arnold Offerhaus GJ, et al. Distinct molecular subtypes of gastric cancer: from Laurén to molecular pathology. Oncotarget. 2018;9(27):19427–42. https://doi.org/10.18632/oncotarget.24827.
Article PubMed PubMed Central Google Scholar
Guo J, Yu W, Su H, Pang X. Genomic landscape of gastric cancer: molecular classification and potential targets. Sci China Life Sci. 2017;60(2):126–37.
Article CAS PubMed Google Scholar
Strand MS, Lockhart AC, Fields RC. Genetics of gastric cancer. Surg Clin North Am. 2017;97(2):345–70.
Li X, Yang Y, Zhang B, Lin X, Fu X, An Y, et al. Lactate metabolism in human health and disease. Sign Transduct Target Ther. 2022;7(1):305.
Liu Y, Zhang Z, Wang J, Chen C, Tang X, Zhu J, et al. Metabolic reprogramming results in abnormal glycolysis in gastric cancer: a review. Onco Targets Ther. 2019;12:1195–204.
Article CAS PubMed PubMed Central Google Scholar
Abbaszadeh Z, Cesmeli S, Biray AC. Crucial players in glycolysis: cancer progress. Gene. 2020;726: 144158.
Article CAS PubMed Google Scholar
Liao ZX, Kempson IM, Hsieh CC, Tseng SJ, Yang PC. Potential therapeutics using tumor-secreted lactate in nonsmall cell lung cancer. Drug Discov Today. 2021;26(11):2508–14.
Article CAS PubMed Google Scholar
Sathe A, Grimes SM, Lau BT, Chen J, Suarez C, Huang RJ, et al. Single-cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment. Clin Cancer Res. 2020;26(11):2640–53.
Article CAS PubMed PubMed Central Google Scholar
Hirschhaeuser F, Sattler UG, Mueller-Klieser W. Lactate: a metabolic key player in cancer. Cancer Res. 2011;71(22):6921–5.
Article CAS PubMed Google Scholar
Xiang R, Rong Y, Ge Y, Song W, Ren J, Fu T. Cell differentiation trajectory predicts patient potential immunotherapy response and prognosis in gastric cancer. Aging (Albany NY). 2021;13(4):5928–45.
Article CAS PubMed Google Scholar
Fischer K, Hoffmann P, Voelkl S, Meidenbauer N, Ammer J, Edinger M, et al. Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood. 2007;109(9):3812–9.
Article CAS PubMed Google Scholar
Certo M, Tsai CH, Pucino V, Ho PC, Mauro C. Lactate modulation of immune responses in inflammatory versus tumour microenvironments. Nat Rev Immunol. 2021;21(3):151–61.
Article CAS PubMed Google Scholar
Quinn WJ, Jiao J, TeSlaa T, Stadanlick J, Wang Z, Wang L, et al. Lactate limits T cell proliferation via the NAD(H) redox state. Cell Rep. 2020. https://doi.org/10.1016/j.celrep.2020.108500.
Article PubMed PubMed Central Google Scholar
Fernandes E, Sores J, Cotton S, Peixoto A, Ferreira D, Freitas R, et al. Esophageal, gastric and colorectal cancers: Looking beyond classical serological biomarkers towards glycoproteomics-assisted precision oncology. Theranostics. 2020;10(11):4903–28.
Article CAS PubMed PubMed Central Google Scholar
Liberzon A, Birger C, Thorvaldsdottir H, Ghandi M, Mesirov JP, Tamayo P. The molecular signatures database (MSigDB) hallmark gene set collection. Cell Syst. 2015;1(6):417–25.
Article CAS PubMed PubMed Central Google Scholar
Liu Z, Lu T, Wang L, Liu L, Li L, Han X. Comprehensive molecular analyses of a novel mutational signature classification system with regard to prognosis, genomic alterations, and immune landscape in glioma. Front Mol Biosci. 2021;8: 682084.
Article CAS PubMed PubMed Central Google Scholar
Liu SJ, Yang YB, Zhou JX, Lin YJ, Pan YL, Pan JH. A novel ferroptosis-related gene risk signature for predicting prognosis and immunotherapy response in gastric cancer. Dis Mark. 2021;2021:2385406.
Iasonos A, Schrag D, Raj GV, Panageas KS. How to build and interpret a nomogram for cancer prognosis. J Clin Oncol. 2008;26(8):1364–70.
Chen L, Huang L, Gu Y, Cang W, Sun P, Xiang Y. Lactate-lactylation hands between metabolic reprogramming and immunosuppression. Int J Mol Sci. 2022. https://doi.org/10.3390/ijms231911943.
Article PubMed PubMed Central Google Scholar
Wang W, Ye LF, Bao H, Hu MT, Han M, Tang HM, et al. Heterogeneity and evolution of tumour immune microenvironment in metastatic gastroesophageal adenocarcinoma. Gastric Cancer. 2022;25(6):1017–30.
Article CAS PubMed PubMed Central Google Scholar
Wang B, Zhang Z, Liu W, Tan B. Targeting regulatory T cells in gastric cancer: pathogenesis, immunotherapy, and prognosis. Biomed Pharmacother. 2023;158: 114180.
Article CAS PubMed Google Scholar
Tao Z, Huang C, Wang D, Wang Q, Gao Q, Zhang H, et al. Lactate induced mesenchymal stem cells activation promotes gastric cancer cells migration and proliferation. Exp Cell Res. 2023;424(1): 113492.
Article CAS PubMed Google Scholar
Shen Y, Yang J, Li J, Shi X, Ouyang L, Tian Y, et al. Carnosine inhibits the proliferation of human gastric cancer SGC-7901 cells through both of the mitochondrial respiration and glycolysis pathways. PLoS ONE. 2014;9(8): e104632.
Article PubMed PubMed Central Google Scholar
Wang ZH, Peng WB, Zhang P, Yang XP, Zhou Q. Lactate in the tumour microenvironment: From immune modulation to therapy. EBioMedicine. 2021;73: 103627.
Article CAS PubMed PubMed Central Google Scholar
Izzo Luke T, Wellen KE. Lactate links metabolism to genes. Nature TN. 7779(2019):574.
Yoda Y, Takeshima H, Niwa T, Kim JG, Ando T, Kushima R, et al. Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer. Gastric Cancer. 2015;18(1):65–76.
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