Microglia Sing the Prelude of Neuroinflammation-Associated Depression

Ganança L, Galfalvy HC, Cisneros-Trujillo S, Basseda Z, Cooper TB, Ren X, Figueira ML, Oquendo MA et al (2021) Relationships between inflammatory markers and suicide risk status in major depression. J Psychiatr Res 134:192–199. https://doi.org/10.1016/j.jpsychires.2020.12.029

Article  PubMed  Google Scholar 

Jha MK, Cai L, Minhajuddin A, Fatt CC, Furman JL, Gadad BS, Mason BL, Greer TL et al (2020) Dysfunctional adaptive immune response in adolescents and young adults with suicide behavior. Psychoneuroendocrinology 111:104487. https://doi.org/10.1016/j.psyneuen.2019.104487

Article  CAS  PubMed  Google Scholar 

Mathers CD, Loncar D (2006) Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3(11):e442

Article  PubMed  Google Scholar 

Malhi GS, Mann JJ (2018) Depression. Lancet 392(10161):2299–2312. https://doi.org/10.1016/s0140-6736(18)31948-2

Article  PubMed  Google Scholar 

Wake H, Moorhouse AJ, Miyamoto A, Nabekura J (2013) Microglia: actively surveying and shaping neuronal circuit structure and function. Trends Neurosci 36(4):209–217

Article  CAS  PubMed  Google Scholar 

Harry GJ (2013) Microglia during development and aging. Pharmacol Ther 139(3):313–326. https://doi.org/10.1016/j.pharmthera.2013.04.013

Article  CAS  PubMed  Google Scholar 

Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454(7203):428–435. https://doi.org/10.1038/nature07201

Article  CAS  PubMed  Google Scholar 

Nusslock R, Miller GE (2016) Early-life adversity and physical and emotional health across the lifespan: a neuroimmune network hypothesis. Biol Psychiat 80(1):23–32. https://doi.org/10.1016/j.biopsych.2015.05.017

Article  PubMed  Google Scholar 

Zindel J, Kubes P (2020) DAMPs, PAMPs, and LAMPs in immunity and sterile inflammation. Annu Rev Pathol 15:493–518. https://doi.org/10.1146/annurev-pathmechdis-012419-032847

Article  CAS  PubMed  Google Scholar 

Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9(1):46–56. https://doi.org/10.1038/nrn2297

Article  CAS  PubMed  Google Scholar 

Miller AH, Maletic V, Raison CL (2009) Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiat 65(9):732–741

Article  CAS  PubMed  Google Scholar 

Maes M (1995) Evidence for an immune response in major depression: a review and hypothesis. Prog Neuropsychopharmacol Biol Psychiatry 19(1):11–38

Article  CAS  PubMed  Google Scholar 

Yirmiya R, Rimmerman N, Reshef R (2015) Depression as a microglial disease. Trends Neurosci 38(10):637–658. https://doi.org/10.1016/j.tins.2015.08.001

Article  CAS  PubMed  Google Scholar 

Mac Giollabhui N, Ng TH, Ellman LM, Alloy LB (2020) The longitudinal associations of inflammatory biomarkers and depression revisited: systematic review, meta-analysis, and meta-regression. Mol Psychiatr 26. https://doi.org/10.1038/s41380-020-00867-4

Colasanto M, Madigan S, Korczak DJ (2020) Depression and inflammation among children and adolescents: a meta-analysis. J Affect Disord 277:940–948. https://doi.org/10.1016/j.jad.2020.09.025

Article  CAS  PubMed  Google Scholar 

Almeida IB, Gomes IA, Shanmugam S, de Moura TR, Magalhães LS, de Aquino LAG, de Souza Araújo AA, Oliveira PD et al (2020) Inflammatory modulation of fluoxetine use in patients with depression: a systematic review and meta-analysis. Cytokine 131:155100. https://doi.org/10.1016/j.cyto.2020.155100

Article  CAS  PubMed  Google Scholar 

Felger JC, Haroon E, Patel TA, Goldsmith DR, Wommack EC, Woolwine BJ, Le NA, Feinberg R et al (2020) What does plasma CRP tell us about peripheral and central inflammation in depression? Mol Psychiatry 25(6):1301–1311. https://doi.org/10.1038/s41380-018-0096-3

Article  CAS  PubMed  Google Scholar 

Zhang HX, Xu YQ, Li YY, Lu MF, Shi SX, Ji JL, Wang LW (2018) Difference in proinflammatory cytokines produced by monocytes between patients with major depressive disorder and healthy controls. J Affect Disord 234:305–310. https://doi.org/10.1016/j.jad.2017.12.099

Article  CAS  PubMed  Google Scholar 

Syed SA, Beurel E, Loewenstein DA, Lowell JA, Craighead WE, Dunlop BW, Mayberg HS, Dhabhar F et al (2018) Defective inflammatory pathways in never-treated depressed patients are associated with poor treatment response. Neuron 5:914-924.e913

Article  Google Scholar 

Alavi M, Grebely J, Matthews GV, Petoumenos K, Yeung B, Day C, Lloyd AR, Van Beek I et al (2012) Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infection. J Gastroenterol Hepatol 27(5):957–965. https://doi.org/10.1111/j.1440-1746.2011.07035.x

Article  CAS  PubMed  Google Scholar 

Musselman DL, Lawson DH, Gumnick JF, Manatunga AK, Penna S, Goodkin RS, Greiner K, Nemeroff CB et al (2001) Paroxetine for the prevention of depression induced by high-dose interferon alfa. N Engl J Med 344(13):961–966. https://doi.org/10.1056/nejm200103293441303

Article  CAS  PubMed  Google Scholar 

Cao P, Chen C, Liu A, Shan Q, Zhu X, Jia C, Peng X, Zhang M et al (2021) Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines. Neuron 109. https://doi.org/10.1016/j.neuron.2021.06.012

Walker AK, Wing EE, Banks WA, Dantzer R (2019) Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice. Mol Psychiatry 24(10):1523–1532. https://doi.org/10.1038/s41380-018-0076-7

Article  CAS  PubMed  Google Scholar 

Aguilar-Valles A, Kim J, Jung S, Woodside B, Luheshi GN (2014) Role of brain transmigrating neutrophils in depression-like behavior during systemic infection. Mol Psychiatry 19(5):599–606. https://doi.org/10.1038/mp.2013.137

Article  CAS  PubMed  Google Scholar 

Setiawan E, Attwells S, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Xu C, Sharma S et al (2018) Association of translocator protein total distribution volume with duration of untreated major depres sive disorder: a cross-sectional study. Lancet Psychiatr 5(4):339–347

Article  Google Scholar 

Zhang L, Hu K, Shao T, Hou L, Zhang S, Ye W, Josephson L, Meyer JH et al (2021) Recent developments on PET radiotracers for TSPO and their applications in neuroimaging. Acta Pharm Sin B 11(2):373–393

Article  CAS  PubMed  Google Scholar 

Böttcher C, Fernández-Zapata C, Snijders GJL, Schlickeiser S, Sneeboer MAM, Kunkel D, De Witte LD, Priller J (2020) Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression. Transl Psychiatry 10(1):310. https://doi.org/10.1038/s41398-020-00992-2

Article  CAS  PubMed  Google Scholar 

Setiawan E, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Rajkowska G, Suridjan I, Kennedy JL et al (2015) Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes. JAMA Psychiat 72(3):268–275. https://doi.org/10.1001/jamapsychiatry.2014.2427

Article  Google Scholar 

Holmes SE, Hinz R, Conen S, Gregory CJ, Matthews JC, Anton-Rodriguez JM, Gerhard A, Talbot PS (2018) Elevated translocator protein in anterior cingulate in major depression and a role for inflammation in suicidal thinking: a positron emission tomography study. Biol Psychiat 83(1):61–69. https://doi.org/10.1016/j.biopsych.2017.08.005

Article  CAS  PubMed  Google Scholar 

Wang H, He Y, Sun Z, Ren S, Liu M, Wang G, Yang J (2022) Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression. J Neuroinflammation 19(1):132. https://doi.org/10.1186/s12974-022-02492-0

Article  PubMed  Google Scholar 

Priller J, Prinz M (2019) Targeting microglia in brain disorders. Science 365(6448):32–33

Article  CAS 

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