Ensuring availability of respiratory medicines in times of European drug shortages

Original Research Article

Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthma

Ekaterina Khaleva

Chris Brightling

Thomas Eiwegger

Alan Altraja

Philippe Bégin

Katharina Blumchen

Apostolos Bossios

Arnaud Bourdin

Anneke Ten Brinke

Guy Brusselle

Roxana Silvia Bumbacea

Andrew Bush

Thomas B Casale

Graham W. Clarke

Rekha Chaudhuri

Kian Fan Chung

Courtney Coleman

Jonathan Corren

Sven-Erik Dahlén

Antoine Deschildre

Ratko Djukanovic

Katrien Eger

Andrew Exley

Louise Fleming

Stephen J Fowler

Erol A Gaillard

Monika Gappa

Atul Gupta

Hans Michael Haitchi

Simone Hashimoto

Liam G Heaney

Gunilla Hedlin

Markaya Henderson

Wen Hua

David J Jackson

Bülent Karadag

Constance Helen Katelaris

Mariko S. Koh

Matthias Volkmar Kopp

Gerard H. Koppelman

Inger Kull

Ramesh J Kurukulaaratchy

Ji-Hyang Lee

Vera Mahler

Mika Mäkelä

Matthew Masoli

Alexander G. Mathioudakis

Angel Mazon

Erik Melén

Katrin Milger

Alexander Moeller

Clare S Murray

Prasad Nagakumar

Parameswaran Nair

Jenny Negus

Antonio Nieto

Nikolaos G. Papadopoulos

James Paton

Mariëlle W Pijnenburg

Katharine C Pike

Celeste Porsbjerg

Anna Rattu

Hitasha Rupani

Franca Rusconi

Niels W Rutjes

Sejal Saglani

Paul Seddon

Salman Siddiqui

Florian Singer

Tomoko Tajiri

Steve Turner

John W Upham

Susanne J.H. Vijverberg

Peter A B Wark

Michael E. Wechsler

Valentyna Yasinska

Graham Roberts

European Respiratory Journal 2400691; DOI: 10.1183/13993003.00691-2024 Published 7 November 2024

We have previously developed Core Outcome Measures sets for Severe Asthma (COMSA) by multi-stakeholder consensus. There are no patient-centred tools to quantify response to biologics for severe asthma. We aimed to develop paediatric and adult CompOsite iNdexes For Response in asthMa (CONFiRM) incorporating clinical parameters and patient…

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